5DB8

Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dA

Summary for 5DB8

Related5DB6 5DB7 5DB9 5DBA 5DBB 5DBC
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total)
Functional Keywordshuman dna polymerase, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
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Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight47809.91
Authors
Koag, M.C.,Lee, S. (deposition date: 2015-08-21, release date: 2015-11-11, Last modification date: 2015-11-18)
Primary citation
Kou, Y.,Koag, M.C.,Lee, S.
N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137:14067-14070, 2015
PubMed: 26517568 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.5b10172
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.547 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25961.2%2.1%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution