7UPH
 
 | | Structure of a ribosome with tethered subunits | | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | Authors: | Kim, D.S, Watkins, A, Bidstrup, E, Lee, J, Topkar, V.V, Kofman, C, Schwarz, K.J, Liu, Y, Pintilie, G, Roney, E, Das, R, Jewett, M.C. | | Deposit date: | 2022-04-15 | | Release date: | 2022-08-17 | | Last modified: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Three-dimensional structure-guided evolution of a ribosome with tethered subunits.
Nat.Chem.Biol., 18, 2022
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5WUV
 | | Crystal structure of Certolizumab Fab | | Descriptor: | heavy chain, light chain | | Authors: | Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y. | | Deposit date: | 2016-12-21 | | Release date: | 2017-06-07 | | Method: | X-RAY DIFFRACTION (1.952 Å) | | Cite: | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
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7L0D
 | | SARS-CoV-2 Main Protease (Mpro) in Complex with ML188 | | Descriptor: | 3C-like proteinase, N-[(1R)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-N-(4-tert-butylphenyl)furan-2-carboxamide | | Authors: | Lockbaum, G.J, Lee, J.M, Reyes, A.C, Nalivaika, E.A, Ali, A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | Deposit date: | 2020-12-11 | | Release date: | 2021-02-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188.
Viruses, 13, 2021
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1JO7
 | | Solution Structure of Influenza A Virus Promoter | | Descriptor: | Influenza A virus promoter RNA | | Authors: | Bae, S.-H, Cheong, H.-K, Lee, J.-H, Cheong, C, Kainosho, M, Choi, B.-S. | | Deposit date: | 2001-07-27 | | Release date: | 2001-09-19 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural features of an influenza virus promoter and their implications for viral RNA synthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
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6KYV
 | | Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION | | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | | Deposit date: | 2019-09-20 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.
Rna Biol., 17, 2020
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7ENY
 | | Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli | | Descriptor: | 7alpha-hydroxysteroid dehydrogenase | | Authors: | Kim, K.-H, Lee, C.W, Pardhe, D.P, Hwang, J, Do, H, Lee, Y.M, Lee, J.H, Oh, T.-J. | | Deposit date: | 2021-04-21 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Crystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding.
J.Steroid Biochem.Mol.Biol., 212, 2021
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7N07
 | | Crystal structure of the apo 3D6 antibody fragment | | Descriptor: | Fab 3D6 heavy chain, Fab 3D6 light chain, SULFATE ION | | Authors: | Cook, J.D, Lee, J.E. | | Deposit date: | 2021-05-25 | | Release date: | 2022-03-30 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
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7N04
 | | Crystal structure of the apo F240 antibody fragment | | Descriptor: | Fab F240 heavy chain, Fab F240 light chain, alpha-D-glucopyranose | | Authors: | Cook, J.D, Lee, J.E. | | Deposit date: | 2021-05-25 | | Release date: | 2022-03-30 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.70000517 Å) | | Cite: | Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
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7N05
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3L4F
 | | Crystal Structure of betaPIX Coiled-Coil Domain and Shank PDZ Complex | | Descriptor: | Rho guanine nucleotide exchange factor 7, SH3 and multiple ankyrin repeat domains protein 1 | | Authors: | Im, Y.J, Kang, G.B, Lee, J.H, Song, H.E, Park, K.R, Kim, E, Song, W.K, Park, D, Eom, S.H. | | Deposit date: | 2009-12-19 | | Release date: | 2010-02-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for asymmetric association of the betaPIX coiled coil and shank PDZ
J.Mol.Biol., 397, 2010
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1XNG
 | | Crystal Structure of NH3-dependent NAD+ synthetase from Helicobacter pylori | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase, ... | | Authors: | Kang, G.B, Kim, Y.S, Im, Y.J, Rho, S.H, Lee, J.H, Eom, S.H. | | Deposit date: | 2004-10-05 | | Release date: | 2005-04-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of NH3-dependent NAD+ synthetase from Helicobacter pylori
Proteins, 58, 2005
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2KM9
 | | Omega conotoxin-FVIA | | Descriptor: | omega_conotoxin-FVIA | | Authors: | Lee, S, Kim, J, Lee, J, Jung, H. | | Deposit date: | 2009-07-25 | | Release date: | 2010-07-28 | | Last modified: | 2011-09-28 | | Method: | SOLUTION NMR | | Cite: | Structure of omega conotoxin-FVIA
To be Published
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5CUF
 | | X-ray crystal structure of SeMet human Sestrin2 | | Descriptor: | Sestrin-2 | | Authors: | Kim, H, An, S, Ro, S.-H, Lee, J.H, Cho, U.-S. | | Deposit date: | 2015-07-24 | | Release date: | 2016-01-13 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains.
Nat Commun, 6, 2015
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3MCD
 | | Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor | | Descriptor: | Cell division topological specificity factor | | Authors: | Kang, G.B, Song, H.E, Kim, M.K, Youn, H.S, Lee, J.G, An, J.Y, Jeon, H, Chun, J.S, Eom, S.H. | | Deposit date: | 2010-03-29 | | Release date: | 2010-05-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor
Mol.Microbiol., 76, 2010
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2AEP
 | | An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FAB heavy chain, ... | | Authors: | Venkatramani, L, Bochkareva, E, Lee, J.T, Gulati, U, Laver, W.G, Bochkarev, A, Air, G.M. | | Deposit date: | 2005-07-23 | | Release date: | 2005-12-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex
J.Mol.Biol., 356, 2006
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3BPM
 | | Crystal Structure of Falcipain-3 with Its inhibitor, Leupeptin | | Descriptor: | Cysteine protease falcipain-3, Leupeptin, SULFATE ION | | Authors: | kerr, I.D, Lee, J.H, Brinen, L.S. | | Deposit date: | 2007-12-18 | | Release date: | 2008-12-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity.
J.Med.Chem., 52, 2009
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3TG0
 | | E. coli alkaline phosphatase with bound inorganic phosphate | | Descriptor: | Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Bobyr, E, Lassila, J.K, Wiersma-Koch, H.I, Fenn, T.D, Lee, J.J, Nikolic-Hughes, I, Hodgson, K.O, Rees, D.C, Hedman, B, Herschlag, D. | | Deposit date: | 2011-08-16 | | Release date: | 2011-11-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
J.Mol.Biol., 415, 2012
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3BPF
 | | Crystal Structure of Falcipain-2 with Its inhibitor, E64 | | Descriptor: | Cysteine protease falcipain-2, GLYCEROL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | | Authors: | kerr, I.D, Lee, J.H, Brinen, L.S. | | Deposit date: | 2007-12-18 | | Release date: | 2008-12-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity.
J.Med.Chem., 52, 2009
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5WUX
 | | TNFalpha-certolizumab Fab | | Descriptor: | Tumor necrosis factor alpha, heavy, light | | Authors: | Heo, Y.S, Lee, J.U. | | Deposit date: | 2016-12-21 | | Release date: | 2017-06-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
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3TIO
 | | Crystal structures of yrdA from Escherichia coli, a homologous protein of gamma-class carbonic anhydrase, show possible allosteric conformations | | Descriptor: | PHOSPHATE ION, Protein YrdA, ZINC ION | | Authors: | Park, H.M, Choi, J.W, Lee, J.E, Jung, C.H, Kim, B.Y, Kim, J.S. | | Deposit date: | 2011-08-21 | | Release date: | 2012-08-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Structures of the gamma-class carbonic anhydrase homologue YrdA suggest a possible allosteric switch
Acta Crystallogr.,Sect.D, 68, 2012
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3TIS
 | | Crystal structures of yrdA from Escherichia coli, a homologous protein of gamma-class carbonic anhydrases, show possible allosteric conformations | | Descriptor: | Protein YrdA, ZINC ION | | Authors: | Park, H.M, Chio, J.W, Lee, J.E, Jung, J.H, Kim, B.Y, Kim, J.S. | | Deposit date: | 2011-08-21 | | Release date: | 2012-08-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of the gamma-class carbonic anhydrase homologue YrdA suggest a possible allosteric switch
Acta Crystallogr.,Sect.D, 68, 2012
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2AXY
 | | Crystal Structure of KH1 domain of human Poly(C)-binding protein-2 with C-rich strand of human telomeric DNA | | Descriptor: | C-rich strand of human telomeric dna, Poly(rC)-binding protein 2 | | Authors: | Du, Z, Lee, J.K, Tjhen, R.J, Li, S, Stroud, R.M, James, T.L. | | Deposit date: | 2005-09-06 | | Release date: | 2005-09-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the First KH Domain of Human Poly(C)-binding Protein-2 in Complex with a C-rich Strand of Human Telomeric DNA at 1.7 A
J.Biol.Chem., 280, 2005
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2B7P
 | | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with phthalic acid | | Descriptor: | PHTHALIC ACID, Probable nicotinate-nucleotide pyrophosphorylase, SULFATE ION | | Authors: | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | | Deposit date: | 2005-10-05 | | Release date: | 2006-02-14 | | Last modified: | 2018-09-19 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Proteins, 63, 2006
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2B7N
 | | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori | | Descriptor: | Probable nicotinate-nucleotide pyrophosphorylase, QUINOLINIC ACID, SULFATE ION | | Authors: | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | | Deposit date: | 2005-10-04 | | Release date: | 2006-02-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Proteins, 63, 2006
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5ZLP
 | | Crystal structure of glutamine synthetase from helicobacter pylori | | Descriptor: | (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Joo, H.K, Lee, J.Y. | | Deposit date: | 2018-03-29 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.93 Å) | | Cite: | Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Sci Rep, 8, 2018
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