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PDB: 98 件

7U14
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TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7EXP
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Crystal structure of zebrafish TRAP1 with AMPPNP and MitoQ
分子名称: 2,3-dimethoxy-5-methyl-6-[10-(triphenyl-$l^{5}-phosphanyl)decyl]cyclohexa-2,5-diene-1,4-dione, COBALT (II) ION, MAGNESIUM ION, ...
著者Lee, H, Yoon, N.G, Kang, B.H, Lee, C.
登録日2021-05-28
公開日2022-01-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site.
J.Am.Chem.Soc., 143, 2021
7MCI
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MoFe protein from Azotobacter vinelandii with a sulfur-replenished cofactor
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
著者Kang, W, Lee, C, Hu, Y, Ribbe, M.W.
登録日2021-04-02
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Evidence of substrate binding and product release via belt-sulfur mobilization of the nitrogenase cofactor
Nat Catal, 5, 2022
2ZXX
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Crystal structure of Cdt1/geminin complex
分子名称: DNA replication factor Cdt1, Geminin
著者Cho, Y, Lee, C, Hong, B.S, Choi, J.M.
登録日2009-01-08
公開日2009-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
1CE3
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PUTATIVE ANCESTRAL PROTEIN ENCODED BY A SINGLE SEQUENCE REPEAT OF THE MULTIDOMAIN PROTEINASE INHIBITOR FROM NICOTIANA ALATA
分子名称: API
著者Scanlon, M.J, Lee, M.C.S, Anderson, M.A, Craik, D.J.
登録日1999-03-14
公開日1999-03-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of a putative ancestral protein encoded by a single sequence repeat from a multidomain proteinase inhibitor gene from Nicotiana alata.
Structure Fold.Des., 7, 1999
2MBC
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Solution Structure of human holo-PRL-3 in complex with vanadate
分子名称: Protein tyrosine phosphatase type IVA 3
著者Jeong, K, Kang, D, Kim, J, Shin, S, Jin, B, Lee, C, Kim, E, Jeon, Y.H, Kim, Y.
登録日2013-07-29
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and backbone dynamics of vanadate-bound PRL-3: comparison of 15N nuclear magnetic resonance relaxation profiles of free and vanadate-bound PRL-3.
Biochemistry, 53, 2014
5E1J
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Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana
分子名称: BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1
著者Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y.
登録日2015-09-29
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.308 Å)
主引用文献Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana.
Nature, 531, 2016
1G4B
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CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM
分子名称: ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV
著者Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H.
登録日2000-10-26
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.
Structure, 9, 2001
1G4A
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CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV
著者Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H.
登録日2000-10-26
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.
Structure, 9, 2001
2L01
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Solution NMR Structure of protein BVU3908 from Bacteroides vulgatus, Northeast Structural Genomics Consortium Target BvR153
分子名称: Uncharacterized protein
著者Eletsky, A, Lee, C, Wang, K, Ciccosanti, T.B, Hamilton, R, Acton, J.B, Xiao, G.B, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-29
公開日2010-08-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of protein BVU3908 from Bacteroides vulgatus
To be Published
1XZY
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Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP)
分子名称: Alpha-hemoglobin stabilizing protein
著者Gell, D.A, Feng, L, Zhou, S, Kong, Y, Lee, C, Weiss, M.J, Shi, Y, Mackay, J.P.
登録日2004-11-12
公開日2004-12-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin
Cell(Cambridge,Mass.), 119, 2004
7C7B
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Crystal structure of human TRAP1 with SJT009
分子名称: 2-azanyl-9-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial
著者Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S.
登録日2020-05-24
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
Acs Med.Chem.Lett., 12, 2021
7C7C
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Crystal structure of human TRAP1 with SJT104
分子名称: 2-azanyl-9-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial
著者Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S.
登録日2020-05-24
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
Acs Med.Chem.Lett., 12, 2021
5YK6
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Crystal Structure of Mmm1
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Maintenance of mitochondrial morphology protein 1
著者Jeong, H, Park, J, Lee, C.
登録日2017-10-12
公開日2018-01-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5YK7
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Crystal Structure of Mdm12-Mmm1 complex
分子名称: Maintenance of mitochondrial morphology protein 1, Mitochondrial distribution and morphology protein 12, PHOSPHATE ION
著者Jeong, H, Park, J, Lee, C.
登録日2017-10-12
公開日2018-01-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.799 Å)
主引用文献Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4MLG
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Structure of RS223-Beta-xylosidase
分子名称: Beta-xylosidase, CALCIUM ION, SULFATE ION
著者Jordan, D, Braker, J, Wagschal, K, Lee, C, Dubrovska, I, Anderson, S, Wawrzak, Z.
登録日2013-09-06
公開日2014-09-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of RS223-Beta-xylosidase
To be Published
2J3K
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Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Ternary Complex II
分子名称: (2E,4R)-4-HYDROXYNON-2-ENAL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent oxidoreductase 2-alkenal reductase
著者Youn, B, Kim, S.J, Moinuddin, S.G, Lee, C, Bedgar, D.L, Harper, A.R, Davin, L.B, Lewis, N.G, Kang, C.
登録日2006-08-22
公開日2006-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic and structural studies of apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase At5g16970.
J. Biol. Chem., 281, 2006
2J3I
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Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Binary Complex
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-DEPENDENT OXIDOREDUCTASE P1
著者Youn, B, Kim, S.J, Moinuddin, S.G, Lee, C, Bedgar, D.L, Harper, A.R, Davin, L.B, Lewis, N.G, Kang, C.
登録日2006-08-21
公開日2006-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic and Structural Studies of Apoform, Binary, and Ternary Complexes of the Arabidopsis Alkenal Double Bond Reductase at5G16970.
J.Biol.Chem., 281, 2006
2J3H
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Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Apo form
分子名称: NADP-DEPENDENT OXIDOREDUCTASE P1
著者Youn, B, Kim, S.J, Moinuddin, S.G, Lee, C, Bedgar, D.L, Harper, A.R, Davin, L.B, Lewis, N.G, Kang, C.
登録日2006-08-21
公開日2006-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic and Structural Studies of Apoform, Binary, and Ternary Complexes of the Arabidopsis Alkenal Double Bond Reductase at5G16970.
J.Biol.Chem., 281, 2006
2J3J
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Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Ternary Complex I
分子名称: 4'-HYDROXYCINNAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent oxidoreductase 2-alkenal reductase
著者Youn, B, Kim, S.J, Moinuddin, S.G, Lee, C, Bedgar, D.L, Harper, A.R, Davin, L.B, Lewis, N.G, Kang, C.
登録日2006-08-21
公開日2006-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic and structural studies of apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase At5g16970.
J. Biol. Chem., 281, 2006
5GYD
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Crystal Structure of Mdm12
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Mitochondrial distribution and morphology protein 12
著者Jeong, H, Park, J, Lee, C.
登録日2016-09-22
公開日2016-11-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex
EMBO Rep., 17, 2016
5GYK
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Crystal Structure of Mdm12-deletion mutant
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Mitochondrial distribution and morphology protein 12
著者Jeong, H, Park, J, Lee, C.
登録日2016-09-22
公開日2016-11-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.596 Å)
主引用文献Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex
EMBO Rep., 17, 2016
2MXD
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Solution structure of VPg of porcine sapovirus
分子名称: Viral protein genome-linked
著者Kim, J, Hwang, H, Min, H, Yun, H, Cho, K, Pelton, J.G, Wemmer, D.E, Lee, C.
登録日2014-12-24
公開日2015-04-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch.
Biochem.Biophys.Res.Commun., 459, 2015
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