1IQO
| Solution structure of MTH1880 from methanobacterium thermoautotrophicum | Descriptor: | HYPOTHETICAL PROTEIN MTH1880 | Authors: | Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W. | Deposit date: | 2001-07-23 | Release date: | 2002-07-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum. Protein Sci., 13, 2004
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1IQS
| Minimized average structure of MTH1880 from Methanobacterium Thermoautotrophicum | Descriptor: | MTH1880 | Authors: | Lee, C.H, Shin, J, Bang, E, Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W. | Deposit date: | 2001-07-29 | Release date: | 2002-07-29 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum. Protein Sci., 13, 2004
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8IDU
| Crystal structure of substrate bound-form dehydroquinate dehydratase from Corynebacterium glutamicum | Descriptor: | 1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID, 3-dehydroquinate dehydratase, GLYCEROL, ... | Authors: | Lee, C.H, Kim, S, Kim, K.-J. | Deposit date: | 2023-02-14 | Release date: | 2023-12-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Biochemical Analysis of 3-Dehydroquinate Dehydratase from Corynebacterium glutamicum . J Microbiol Biotechnol., 33, 2023
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8IDR
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6CNN
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6CNO
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6CNM
| Cryo-EM structure of the human SK4/calmodulin channel complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Lee, C.H, MacKinnon, R. | Deposit date: | 2018-03-08 | Release date: | 2018-05-02 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science, 360, 2018
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3TNU
| Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14) | Descriptor: | Keratin, type I cytoskeletal 14, type II cytoskeletal 5 | Authors: | Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A. | Deposit date: | 2011-09-02 | Release date: | 2012-06-20 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (3.005 Å) | Cite: | Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat.Struct.Mol.Biol., 19, 2012
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8ZUG
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1RYJ
| Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526. | Descriptor: | unknown | Authors: | Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-22 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | AN NMR APPROACH TO STRUCTURAL PROTEOMICS Proc.Natl.Acad.Sci.USA, 99, 2002
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2BTN
| Crystal Structure and Catalytic Mechanism of the Quorum-Quenching N- Acyl Homoserine Lactone Hydrolase | Descriptor: | AIIA-LIKE PROTEIN, GLYCEROL, ZINC ION | Authors: | Kim, M.H, Choi, W.C, Kang, H.O, Lee, J.S, Kang, B.S, Kim, K.J, Derewenda, Z.S, Oh, T.K, Lee, C.H, Lee, J.K. | Deposit date: | 2005-06-03 | Release date: | 2005-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase. Proc.Natl.Acad.Sci.USA, 102, 2005
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2BR6
| Crystal Structure of Quorum-Quenching N-Acyl Homoserine Lactone Lactonase | Descriptor: | AIIA-LIKE PROTEIN, GLYCEROL, HOMOSERINE LACTONE, ... | Authors: | Kim, M.H, Choi, W.C, Kang, H.O, Kang, B.S, Kim, K.J, Derewenda, Z.S, Lee, J.K, Oh, T.K, Lee, C.H. | Deposit date: | 2005-05-03 | Release date: | 2005-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase. Proc.Natl.Acad.Sci.USA, 102, 2005
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9B1H
| Human urate transporter 1 URAT1 in complex with lesinurad | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, lesinurad | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1K
| Urate bound human URAT1 in the occluded state | Descriptor: | Solute carrier family 22 member 12, URIC ACID | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1O
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9B1J
| Urate bound human URAT1 in the inward-facing state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Solute carrier family 22 member 12, ... | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1G
| Human urate transporter 1 URAT1 in complex with dotinurad | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, dotinurad | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1L
| Urate bound human URAT1 in the outward-facing state. | Descriptor: | Solute carrier family 22 member 12, URIC ACID | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1N
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9B1F
| Human urate transporter 1 URAT1 in apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12 | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1I
| Human urate transporter 1 URAT1 in complex with verinurad | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, verinurad | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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9B1M
| Pyrazinoate bound human URAT1 in the inward-facing state (site1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12 | Authors: | Dai, Y, Lee, C.H. | Deposit date: | 2024-03-13 | Release date: | 2024-09-18 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Res., 2024
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8EX5
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8EX6
| Human S1P transporter Spns2 in an inward-facing open conformation (state 1*) | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2 | Authors: | Ahmed, S, Zhao, H, Dai, Y, Lee, C.H. | Deposit date: | 2022-10-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186, 2023
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8EX4
| Human S1P transporter Spns2 in an inward-facing open conformation (state 1) | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2 | Authors: | Ahmed, S, Zhao, H, Dai, Y, Lee, C.H. | Deposit date: | 2022-10-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186, 2023
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