2Z94
| Complex structure of SARS-CoV 3C-like protease with TDT | Descriptor: | 4-methylbenzene-1,2-dithiol, Replicase polyprotein 1ab, ZINC ION | Authors: | Lee, C.C, Wang, A.H. | Deposit date: | 2007-09-17 | Release date: | 2007-12-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors Febs Lett., 581, 2007
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2Z9K
| Complex structure of SARS-CoV 3C-like protease with JMF1600 | Descriptor: | (dimethylamino)(hydroxy)zinc', 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Lee, C.C, Wang, A.H. | Deposit date: | 2007-09-20 | Release date: | 2007-12-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
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2ZTY
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2ZTX
| Complex structure of CVB3 3C protease with EPDTC | Descriptor: | 3C proteinase, zinc(II)hydrogensulfide | Authors: | Lee, C.C, Wang, A.H.-J. | Deposit date: | 2008-10-10 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284, 2009
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2Z9J
| Complex structure of SARS-CoV 3C-like protease with EPDTC | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide | Authors: | Lee, C.C, Wang, A.H. | Deposit date: | 2007-09-20 | Release date: | 2007-12-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
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2ZU1
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6VHG
| Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrazolo[1,5-a]pyrimidine inhibitor | Descriptor: | 3-(3,4-dimethoxyphenyl)-N~5~-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine, ACETATE ION, CHLORIDE ION, ... | Authors: | Lee, C.C, Spraggon, G. | Deposit date: | 2020-01-09 | Release date: | 2020-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma. Acs Med.Chem.Lett., 11, 2020
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6JP7
| Human antibody 32D6 Fab in complex with PEG | Descriptor: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, HEXAETHYLENE GLYCOL, immunoglobulin Fab heavy chain, ... | Authors: | Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. | Deposit date: | 2019-03-26 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.909 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6JU0
| Mouse antibody 3.3 Fab in complex with PEG | Descriptor: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Fab heavy chain, ... | Authors: | Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. | Deposit date: | 2019-04-12 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6JWC
| Mouse antibody 2B5 Fab in complex with PEG | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ... | Authors: | Lee, C.C, Ko, T.P, Su, Y.C, Lin, L.L, Roffler, S.R, Wang, A.H.J. | Deposit date: | 2019-04-19 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6WYS
| Lon protease proteolytic domain | Descriptor: | Lon protease homolog, mitochondrial, SULFATE ION | Authors: | Lee, C.C, Spraggon, G. | Deposit date: | 2020-05-13 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.229 Å) | Cite: | Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
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6WZV
| Lon protease proteolytic domain | Descriptor: | Lon protease homolog, mitochondrial, N-[(1R)-1-borono-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-D-phenylalaninamide, ... | Authors: | Lee, C.C, Spraggon, G. | Deposit date: | 2020-05-14 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
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6X27
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6X1M
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3Q6M
| Crystal Structure of Human MC-HSP90 in C2221 Space Group | Descriptor: | Heat shock protein HSP 90-alpha, SULFATE ION | Authors: | Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J. | Deposit date: | 2011-01-03 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The hexameric structures of human heat shock protein 90 Plos One, 6, 2011
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3Q6N
| Crystal Structure of Human MC-HSP90 in P21 space group | Descriptor: | Heat shock protein HSP 90-alpha, SULFATE ION | Authors: | Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J. | Deposit date: | 2011-01-03 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | The hexameric structures of human heat shock protein 90 Plos One, 6, 2011
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5XHV
| Crystal Structure Of Fab S40 In Complex With Influenza Hemagglutinin, HA1 subunit. | Descriptor: | Hemagglutinin, S40 heavy chain, S40 light chain | Authors: | Lee, C.C, Wang, A.H.J, Yu, C.M, Yang, A.S. | Deposit date: | 2017-04-24 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries. Sci Rep, 7, 2017
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4Z55
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5Z1X
| Crystal Structure of Laccase from Cerrena sp. RSD1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Lee, C.C, Wu, M.H, Ho, T.H, Wang, A.H.J. | Deposit date: | 2017-12-28 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Kinetic analysis and structural studies of a high-efficiency laccase fromCerrenasp. RSD1. FEBS Open Bio, 8, 2018
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5Z22
| Crystal Structure of Laccase from Cerrena sp. RSD1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Lee, C.C, Wu, M.H, Ho, T.H, Wang, A.H.J. | Deposit date: | 2017-12-28 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Enhancement of laccase activity by pre-incubation with organic solvents. Sci Rep, 9, 2019
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6A4K
| Human antibody 32D6 Fab in complex with H1N1 influenza A virus HA1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. | Deposit date: | 2018-06-20 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells. Sci Rep, 9, 2019
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2IJM
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5HXN
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M and E75A mutants) from the Wild Tomato Solanum habrochaites | Descriptor: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic | Authors: | Lee, C.C, Chan, Y.T, Wang, A.H.J. | Deposit date: | 2016-01-31 | Release date: | 2017-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase. Acs Omega, 2, 2017
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5HXO
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase with D71M, E75A and H103Y Mutants | Descriptor: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic | Authors: | Lee, C.C, Chan, Y.T, Wang, A.H.J. | Deposit date: | 2016-01-31 | Release date: | 2017-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase. Acs Omega, 2, 2017
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5HXT
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP and DMSPP | Descriptor: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... | Authors: | Lee, C.C, Chan, Y.T, Wang, A.H.J. | Deposit date: | 2016-01-31 | Release date: | 2017-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase Acs Omega, 2, 2017
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