8EX6
 
 | | Human S1P transporter Spns2 in an inward-facing open conformation (state 1*) | | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2 | | Authors: | Ahmed, S, Zhao, H, Dai, Y, Lee, C.H. | | Deposit date: | 2022-10-24 | | Release date: | 2023-05-31 | | Last modified: | 2023-06-28 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
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8EX4
 | | Human S1P transporter Spns2 in an inward-facing open conformation (state 1) | | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2 | | Authors: | Ahmed, S, Zhao, H, Dai, Y, Lee, C.H. | | Deposit date: | 2022-10-24 | | Release date: | 2023-05-31 | | Last modified: | 2023-06-28 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
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8EX5
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8EX7
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5XQH
 | | Crystal structure of truncated human Rogdi | | Descriptor: | Protein rogdi homolog | | Authors: | Lee, H, Lee, C. | | Deposit date: | 2017-06-07 | | Release date: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz Syndrome
Sci Rep, 7, 2017
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7X14
 | | Crystal structure of phospho-FFAT motif of MIGA2 bound to VAPB | | Descriptor: | MIGA2 phospho FFAT motif, SULFATE ION, Vesicle-associated membrane protein-associated protein B | | Authors: | Kim, H, Lee, C. | | Deposit date: | 2022-02-23 | | Release date: | 2022-09-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.675 Å) | | Cite: | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites.
Nat Commun, 13, 2022
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5Z2E
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5Z2F
 | | NADPH/PDA bound Dihydrodipicolinate reductase from Paenisporosarcina sp. TG-14 | | Descriptor: | Dihydrodipicolinate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID | | Authors: | Lee, J.H, Lee, C.W, Park, S. | | Deposit date: | 2018-01-02 | | Release date: | 2018-06-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of dihydrodipicolinate reductase (PaDHDPR) from Paenisporosarcina sp. TG-14: structural basis for NADPH preference as a cofactor
Sci Rep, 8, 2018
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4TLL
 | | Crystal structure of GluN1/GluN2B NMDA receptor, structure 1 | | Descriptor: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | | Authors: | Gouaux, E, Lee, C.-H, Lu, W. | | Deposit date: | 2014-05-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
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4TLM
 | | Crystal structure of GluN1/GluN2B NMDA receptor, structure 2 | | Descriptor: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | | Authors: | Gouaux, E, Lee, C.-H, Lu, W. | | Deposit date: | 2014-05-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.77 Å) | | Cite: | NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
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1W3E
 | | Ribosomal L30e of Thermococcus celer, P59A mutant | | Descriptor: | 50S RIBOSOMAL PROTEIN L30E | | Authors: | Ma, H.W, Lee, C.F, Allen, M.D, Bycroft, M, Wong, K.B. | | Deposit date: | 2004-07-15 | | Release date: | 2006-10-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Role of Proline Residues in Thermostability of T. Celer L30E Protein
To be Published
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2ZY5
 | | R487A mutant of L-aspartate beta-decarboxylase | | Descriptor: | L-aspartate beta-decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J. | | Deposit date: | 2009-01-13 | | Release date: | 2009-01-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009
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2ZY2
 | | dodecameric L-aspartate beta-decarboxylase | | Descriptor: | L-aspartate 4-carboxylyase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J. | | Deposit date: | 2009-01-13 | | Release date: | 2009-01-27 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009
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2ZY3
 | | dodecameric L-aspartate beta-decarboxylase | | Descriptor: | L-aspartate beta-decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J. | | Deposit date: | 2009-01-13 | | Release date: | 2009-01-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009
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2ZY4
 | | dodecameric L-aspartate beta-decarboxylase | | Descriptor: | CHLORIDE ION, L-aspartate beta-decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J. | | Deposit date: | 2009-01-13 | | Release date: | 2009-01-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009
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2EWT
 | | Crystal structure of the DNA-binding domain of BldD | | Descriptor: | SULFATE ION, putative DNA-binding protein | | Authors: | Kim, I.K, Lee, C.J, Kim, M.K, Kim, J.M, Kim, J.H, Yim, H.S, Cha, S.S, Kang, S.O. | | Deposit date: | 2005-11-07 | | Release date: | 2006-06-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Crystal structure of the DNA-binding domain of BldD, a central regulator of aerial mycelium formation in Streptomyces coelicolor A3(2)
Mol.Microbiol., 60, 2006
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2VGP
 | | Crystal structure of Aurora B kinase in complex with a aminothiazole inhibitor | | Descriptor: | 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzamide, INNER CENTROMERE PROTEIN A, SERINE/THREONINE-PROTEIN KINASE 12-A | | Authors: | Andersen, C.B, Wan, Y, Chang, J.W, Lee, C, Liu, Y, Sessa, F, Villa, F, Nallan, L, Musacchio, A, Gray, N.S. | | Deposit date: | 2007-11-15 | | Release date: | 2008-02-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Discovery of Selective Aminothiazole Aurora Kinase Inhibitors
Acs Chem.Biol., 3, 2008
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1KOZ
 | | SOLUTION STRUCTURE OF OMEGA-GRAMMOTOXIN SIA | | Descriptor: | Voltage-dependent Channel Inhibitor | | Authors: | Takeuchi, K, Park, E.J, Lee, C.W, Kim, J.I, Takahashi, H, Swartz, K.J, Shimada, I. | | Deposit date: | 2001-12-25 | | Release date: | 2002-08-28 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel.
J.Mol.Biol., 321, 2002
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3E7L
 | | Crystal structure of sigma54 activator NtrC4's DNA binding domain | | Descriptor: | Transcriptional regulator (NtrC family), ZINC ION | | Authors: | Batchelor, J.D, Doucleff, M, Lee, C.-J, Matsubara, K, De Carlo, S, Heideker, J, Lamers, M.M, Pelton, J.G, Wemmer, D.E. | | Deposit date: | 2008-08-18 | | Release date: | 2008-11-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.252 Å) | | Cite: | Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.
J.Mol.Biol., 384, 2008
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5U86
 | | Structure of the Aquifex aeolicus LpxC/LPC-069 complex | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)benzamide, ... | | Authors: | Najeeb, J, Lee, C.-J, Zhou, P. | | Deposit date: | 2016-12-13 | | Release date: | 2017-08-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.
MBio, 8, 2017
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4KSD
 | | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain | | Descriptor: | Multidrug resistance protein 1A, R2 protein | | Authors: | Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G. | | Deposit date: | 2013-05-17 | | Release date: | 2013-07-31 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (4.1001 Å) | | Cite: | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4KSC
 | | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain | | Descriptor: | Multidrug resistance protein 1A | | Authors: | Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G. | | Deposit date: | 2013-05-17 | | Release date: | 2013-07-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4KSB
 | | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain | | Descriptor: | Multidrug resistance protein 1A | | Authors: | Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G. | | Deposit date: | 2013-05-17 | | Release date: | 2013-07-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8001 Å) | | Cite: | Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
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7YAT
 | | CryoEM tetra protofilament structure of the hamster prion 108-144 fibril | | Descriptor: | Major prion protein | | Authors: | Chen, E.H.-L, Kao, S.-W, Lee, C.-H, Huang, J.Y.C, Chen, R.P.-Y, Wu, K.-P. | | Deposit date: | 2022-06-28 | | Release date: | 2022-07-27 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | 2.2 angstrom Cryo-EM Tetra-Protofilament Structure of the Hamster Prion 108-144 Fibril Reveals an Ordered Water Channel in the Center.
J.Am.Chem.Soc., 144, 2022
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4ATV
 | | STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH | | Descriptor: | DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION | | Authors: | Drew, D, Lee, C, Iwata, S, Cameron, A.D. | | Deposit date: | 2012-05-10 | | Release date: | 2013-07-10 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
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