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PDB: 412 件

7DVN
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Crystal structure of a MarR family protein in complex with a lipid-like effector molecule from the psychrophilic bacterium Paenisporosarcina sp. TG-14
分子名称: MarR family transcriptional regulator, PALMITIC ACID
著者Lee, C.W, Hwang, J, Do, H, Lee, J.H.
登録日2021-01-14
公開日2021-11-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule.
Iucrj, 8, 2021
3Q6N
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Crystal Structure of Human MC-HSP90 in P21 space group
分子名称: Heat shock protein HSP 90-alpha, SULFATE ION
著者Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J.
登録日2011-01-03
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献The hexameric structures of human heat shock protein 90
Plos One, 6, 2011
3Q6M
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Crystal Structure of Human MC-HSP90 in C2221 Space Group
分子名称: Heat shock protein HSP 90-alpha, SULFATE ION
著者Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J.
登録日2011-01-03
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The hexameric structures of human heat shock protein 90
Plos One, 6, 2011
4PX6
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BU of 4px6 by Molmil
SYK catalytic domain in complex with a potent pyridopyrimidinone inhibitor
分子名称: 7-{[(1R,2S)-2-aminocyclohexyl]amino}-5-(1H-indol-7-ylamino)pyrido[4,3-d]pyrimidin-4(3H)-one, Tyrosine-protein kinase SYK
著者Lee, C.C.
登録日2014-03-21
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Syk inhibitors with high potency in presence of blood.
Bioorg.Med.Chem.Lett., 24, 2014
5U6O
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Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel
分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2016-12-08
公開日2017-01-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5HXT
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Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP and DMSPP
分子名称: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ...
著者Lee, C.C, Chan, Y.T, Wang, A.H.J.
登録日2016-01-31
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
Acs Omega, 2, 2017
6ABT
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Crystal structure of transcription factor from Listeria monocytogenes
分子名称: PadR family transcriptional regulator
著者Lee, C, Hong, M.
登録日2018-07-23
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
6JP7
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Human antibody 32D6 Fab in complex with PEG
分子名称: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, HEXAETHYLENE GLYCOL, immunoglobulin Fab heavy chain, ...
著者Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J.
登録日2019-03-26
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.909 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
6JU0
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Mouse antibody 3.3 Fab in complex with PEG
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Fab heavy chain, ...
著者Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J.
登録日2019-04-12
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
6JWC
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Mouse antibody 2B5 Fab in complex with PEG
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ...
著者Lee, C.C, Ko, T.P, Su, Y.C, Lin, L.L, Roffler, S.R, Wang, A.H.J.
登録日2019-04-19
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
5HXN
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Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M and E75A mutants) from the Wild Tomato Solanum habrochaites
分子名称: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
著者Lee, C.C, Chan, Y.T, Wang, A.H.J.
登録日2016-01-31
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase.
Acs Omega, 2, 2017
5HXO
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Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase with D71M, E75A and H103Y Mutants
分子名称: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
著者Lee, C.C, Chan, Y.T, Wang, A.H.J.
登録日2016-01-31
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase.
Acs Omega, 2, 2017
2L14
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Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
分子名称: CREB-binding protein, Cellular tumor antigen p53
著者Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2010-07-22
公開日2010-11-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
1T1T
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BU of 1t1t by Molmil
Solution Structure of Kurtoxin
分子名称: Kurtoxin
著者Lee, C.W, Min, H.J, Cho, E.M, Kohno, T, Eu, Y.J, Kim, J.I.
登録日2004-04-18
公開日2005-06-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of kurtoxin
To be Published
3NOW
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BU of 3now by Molmil
UNC-45 from Drosophila melanogaster
分子名称: UNC-45 protein, SD10334p
著者Lee, C.F, Hauenstein, A.V, Fleming, J.K, Gasper, W.C, Engelke, V, Banumathi, S, Bernstein, S.I, Huxford, T.
登録日2010-06-25
公開日2011-03-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.992 Å)
主引用文献X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster.
Structure, 19, 2011
2IJM
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Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Focal Adhesion Kinase 1
著者Lee, C.C.
登録日2006-09-29
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds
To be Published
1LA4
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BU of 1la4 by Molmil
Solution Structure of SGTx1
分子名称: SGTx1
著者Lee, C.W, Roh, S.H, Kim, S, Endoh, H, Kodera, Y, Maeda, T, Swartz, K.J, Kim, J.I.
登録日2002-03-28
公開日2003-11-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating
Biochemistry, 43, 2004
2LKP
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BU of 2lkp by Molmil
solution structure of apo-NmtR
分子名称: HTH-type transcriptional regulator NmtR
著者Lee, C, Giedroc, D.
登録日2011-10-18
公開日2012-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery.
Biochemistry, 51, 2012
3TNU
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Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
分子名称: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
著者Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A.
登録日2011-09-02
公開日2012-06-20
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
5H20
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BU of 5h20 by Molmil
X-ray structure of PadR-like Transcription factor from bacteroid fragilis
分子名称: ISOPROPYL ALCOHOL, PHOSPHATE ION, Putative PadR-family transcriptional regulatory protein, ...
著者Lee, C, Hong, M.
登録日2016-10-13
公開日2017-03-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis.
Biochem. Biophys. Res. Commun., 483, 2017
5XEF
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BU of 5xef by Molmil
Crystal structure of flagellar chaperone from bacteria
分子名称: Flagellar protein fliS
著者Lee, C, Hong, M.
登録日2017-04-05
公開日2018-06-27
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the flagellar chaperone FliS from Bacillus cereus and an invariant proline critical for FliS dimerization and flagellin recognition
Biochem. Biophys. Res. Commun., 487, 2017
5GWG
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Solution structure of rattusin
分子名称: Defensin alpha-related sequence 1
著者Lee, C.W, Min, H.J.
登録日2016-09-11
公開日2017-04-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges
Sci Rep, 7, 2017
2L6I
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Solution structure of coronaviral stem-loop 2 (SL2)
分子名称: RNA (5'-R(*GP*AP*UP*CP*UP*CP*UP*UP*GP*UP*AP*GP*AP*UP*CP*A)-3')
著者Lee, C, Li, L, Giedroc, D.P.
登録日2010-11-21
公開日2011-03-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold.
Febs Lett., 585, 2011
2HIW
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Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
分子名称: 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM, Proto-oncogene tyrosine-protein kinase ABL1
著者Lee, C.
登録日2006-06-29
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A general strategy for creating
Chem.Biol., 13, 2006
7C8T
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Complex Structure of SARS-CoV-2 3CL Protease with TG-0205221
分子名称: 3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE
著者Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H.
登録日2020-06-03
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19
To Be Published

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件を2024-05-29に公開中

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