1YII
 
 | | Crystal Structures of Chicken Annexin V in Complex with Ca2+ | | Descriptor: | Annexin A5, CALCIUM ION, SULFATE ION | | Authors: | Ortlund, E.A, Chai, G, Genge, B, Wu, L.N.Y, Wuthier, R.E, Lebioda, L. | | Deposit date: | 2005-01-11 | | Release date: | 2005-03-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Crystal Structures of Chicken Annexin A5 in Complex with Functional Modifiers Ca2+ and Zn2+ Reveal Zn2+ Induced Formation of Non-Planar Assemblies
Annexins, 1, 2005
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1YPV
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4PGA
 | | GLUTAMINASE-ASPARAGINASE FROM PSEUDOMONAS 7A | | Descriptor: | AMMONIUM ION, GLUTAMINASE-ASPARAGINASE, SULFATE ION | | Authors: | Jakob, C.G, Lewinski, K, Lacount, M.W, Roberts, J, Lebioda, L. | | Deposit date: | 1997-01-14 | | Release date: | 1997-07-23 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Ion binding induces closed conformation in Pseudomonas 7A glutaminase-asparaginase (PGA): crystal structure of the PGA-SO4(2-)-NH4+ complex at 1.7 A resolution.
Biochemistry, 36, 1997
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1HW4
 | | STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS | | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE | | Authors: | Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.
J.Biol.Chem., 276, 2001
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1IW2
 | | X-ray structure of Human Complement Protein C8gamma at pH=7.O | | Descriptor: | Complement Protein C8gamma | | Authors: | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | | Deposit date: | 2002-04-11 | | Release date: | 2002-06-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.
Biochemistry, 41, 2002
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1LF7
 | | Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution | | Descriptor: | CITRIC ACID, Complement Protein C8gamma | | Authors: | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | | Deposit date: | 2002-04-10 | | Release date: | 2002-06-12 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.
Biochemistry, 41, 2002
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3O89
 | | Crystal Structure of Sperm Whale Myoglobin G65T | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Huang, X, Lovelace, L, Lebioda, L. | | Deposit date: | 2010-08-02 | | Release date: | 2011-12-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Investigations of Structural Factors that Influence the Mechanism of Halophenol Dehalogenation using 'Peroxidase-Like' Myoglobin mutants and 'Myoglobin-Like' Amphitrite ornata Dehaloperoxidase Mutants
TO BE PUBLISHED
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3HVM
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2QOS
 | | Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8 | | Descriptor: | Complement component 8, gamma polypeptide, Complement component C8 alpha chain | | Authors: | Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L. | | Deposit date: | 2007-07-20 | | Release date: | 2007-10-16 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding.
Mol.Immunol., 45, 2008
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2RD7
 | | Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins | | Descriptor: | CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain | | Authors: | Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. | | Deposit date: | 2007-09-21 | | Release date: | 2008-05-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
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2RDA
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2R8U
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2RD8
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3UJF
 | | Asymmetric complex of human neuron specific enolase-4-PGA/PEP | | Descriptor: | 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, MAGNESIUM ION, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-11-07 | | Release date: | 2012-08-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJR
 | | Asymmetric complex of human neuron specific enolase-5-PGA/PEP | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-11-08 | | Release date: | 2012-08-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJE
 | | Asymmetric complex of human neuron specific enolase-3-PGA/PEP | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-11-07 | | Release date: | 2012-08-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UCC
 | | Asymmetric complex of human neuron specific enolase-1-PGA/PEP | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-10-26 | | Release date: | 2012-08-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UCD
 | | Asymmetric complex of human neuron specific enolase-2-PGA/PEP | | Descriptor: | 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, MAGNESIUM ION, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-10-26 | | Release date: | 2012-08-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3UJS
 | | Asymmetric complex of human neuron specific enolase-6-PGA/PEP | | Descriptor: | (2R)-2-(phosphonooxy)propanoic acid, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. | | Deposit date: | 2011-11-08 | | Release date: | 2012-08-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
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3OJY
 | | Crystal Structure of Human Complement Component C8 | | Descriptor: | CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ... | | Authors: | Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L. | | Deposit date: | 2010-08-23 | | Release date: | 2011-04-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
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3QUS
 | | Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ATPgS | | Descriptor: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Formate--tetrahydrofolate ligase, MALEIC ACID, ... | | Authors: | Celeste, L.R, Chai, G, Bielak, M, Lovelace, L.L, Lebioda, L. | | Deposit date: | 2011-02-24 | | Release date: | 2011-12-14 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Crystal Strucutre of N10-Formyltetrahydrofolate Synthetase with ATPgS
To be Published
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3OB7
 | | Human Thymidylate Synthase R163K with Cys 195 covalently modified by Glutathione | | Descriptor: | GLUTATHIONE, PHOSPHATE ION, Thymidylate synthase | | Authors: | Gibson, L.M, Celeste, L.R, Lovelace, L.L, Lebioda, L. | | Deposit date: | 2010-08-06 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding.
Acta Crystallogr.,Sect.D, 67, 2011
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2ONB
 | | Human Thymidylate Synthase at low salt conditions with PDPA bound | | Descriptor: | 1,2-ETHANEDIOL, PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID), SULFATE ION, ... | | Authors: | Lovelace, L.L, Gibson, L.M, Lebioda, L. | | Deposit date: | 2007-01-23 | | Release date: | 2007-04-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Cooperative Inhibition of Human Thymidylate Synthase by Mixtures of Active Site Binding and Allosteric Inhibitors
Biochemistry, 46, 2007
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2OVD
 | | Crystal Structure of Human Complement Protein C8gamma with Laurate | | Descriptor: | Complement component 8, gamma polypeptide, LAURIC ACID | | Authors: | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | | Deposit date: | 2007-02-13 | | Release date: | 2007-05-22 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
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2OVE
 | | Crystal Structure of Recombinant Human Complement Protein C8gamma | | Descriptor: | Complement component 8, gamma polypeptide | | Authors: | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | | Deposit date: | 2007-02-13 | | Release date: | 2007-05-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
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