2RHB
 
 | | Crystal structure of Nsp15-H234A mutant- Hexamer in asymmetric unit | | Descriptor: | Uridylate-specific endoribonuclease | | Authors: | Palaninathan, S, Bhardwaj, K, Alcantara, J.M.O, Guarino, L, Yi, L.L, Kao, C.C, Sacchettini, J. | | Deposit date: | 2007-10-08 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15.
J.Biol.Chem., 283, 2008
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4OAP
 | | An Axe2 mutant (W190I), an acetyl-xylooligosaccharide esterase from Geobacillus Stearmophilus | | Descriptor: | ACETATE ION, Acetyl xylan esterase, CHLORIDE ION, ... | | Authors: | Lansky, S, Alalouf, O, Solomon, H.V, Belrhali, H, Shoham, Y, Shoham, G. | | Deposit date: | 2014-01-06 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | An Axe2 mutant (W190I), an acetyl-xylooligosaccharide esterase from Geobacillus Stearmophilus
To be Published
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4OAJ
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4OAO
 | | A mutant of Axe2 (R55A), and acetyl-xylooligosaccharide esterase from Geobacillus Stearmophilus | | Descriptor: | Acetyl xylan esterase, CHLORIDE ION, GLYCEROL | | Authors: | Lansky, S, Alalouf, O, Solomon, H.V, Belrhali, H, Shoham, Y, Shoham, G. | | Deposit date: | 2014-01-06 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | A mutant of Axe2 (R55A), and acetyl-xylooligosaccharide esterase from Geobacillus Stearmophilus
To be Published
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4AS0
 | | Cyclometalated Phthalimides as Protein Kinase Inhibitors | | Descriptor: | PHTALIMIDE-RUTHENIUM COMPLEX, SERINE/THREONINE-PROTEIN KINASE PIM-1 | | Authors: | Blanck, S, Geisselbrecht, Y, Middel, S, Mietke, T, Harms, K, Essen, L.-O, Meggers, E. | | Deposit date: | 2012-04-27 | | Release date: | 2012-10-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Bioactive Cyclometalated Phthalimides: Design, Synthesis and Kinase Inhibition.
Dalton Trans, 41, 2012
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1EGS
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4BI2
 | | Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | | Authors: | Langdon, S.R, Westwood, I.M, van Montfort, R.L.M, Brown, N, Blagg, J. | | Deposit date: | 2013-04-09 | | Release date: | 2013-05-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Scaffold-Focused Virtual Screening: Prospective Application to the Discovery of Ttk Inhibitors.
J.Chem.Inf.Model, 53, 2013
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4BHZ
 | | Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | | Authors: | Langdon, S.R, Westwood, I.M, van Montfort, R.L.M, Brown, N, Blagg, J. | | Deposit date: | 2013-04-09 | | Release date: | 2013-05-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Scaffold-Focused Virtual Screening: Prospective Application to the Discovery of Ttk Inhibitors.
J.Chem.Inf.Model, 53, 2013
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4BI0
 | | Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 5H-pyrimido[5,4-b]indole, ... | | Authors: | Langdon, S.R, Westwood, I.M, van Montfort, R.L.M, Brown, N, Blagg, J. | | Deposit date: | 2013-04-09 | | Release date: | 2013-05-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Scaffold-Focused Virtual Screening: Prospective Application to the Discovery of Ttk Inhibitors.
J.Chem.Inf.Model, 53, 2013
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4BI1
 | | Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | | Authors: | Langdon, S.R, Westwood, I.M, van Montfort, R.L.M, Brown, N, Blagg, J. | | Deposit date: | 2013-04-09 | | Release date: | 2013-05-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Scaffold-Focused Virtual Screening: Prospective Application to the Discovery of Ttk Inhibitors.
J.Chem.Inf.Model, 53, 2013
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4UQZ
 | | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | | Descriptor: | ACETATE ION, HSIB1, HSIE1 | | Authors: | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | | Deposit date: | 2014-06-25 | | Release date: | 2014-10-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.599 Å) | | Cite: | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
RNA, 20, 2014
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4V9D
 | | Structures of the bacterial ribosome in classical and hybrid states of tRNA binding | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Dunkle, J.A, Wang, L, Feldman, M.B, Pulk, A, Chen, V.B, Kapral, G.J, Noeske, J, Richardson, J.S, Blanchard, S.C, Cate, J.H.D. | | Deposit date: | 2012-07-31 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.
Science, 332, 2011
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6OCB
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3MWP
 | | Nucleoprotein structure of lassa fever virus | | Descriptor: | Nucleoprotein, ZINC ION | | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | | Deposit date: | 2010-05-06 | | Release date: | 2010-12-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.795 Å) | | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
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3MX5
 | | Lassa fever virus nucleoprotein complexed with UTP | | Descriptor: | Nucleoprotein, URIDINE 5'-TRIPHOSPHATE, ZINC ION | | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | | Deposit date: | 2010-05-06 | | Release date: | 2010-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
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3MWT
 | | Crystal structure of Lassa fever virus nucleoprotein in complex with Mn2+ | | Descriptor: | MANGANESE (II) ION, Nucleoprotein, ZINC ION | | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | | Deposit date: | 2010-05-06 | | Release date: | 2010-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.982 Å) | | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
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3MX2
 | | Lassa fever virus Nucleoprotein complexed with dTTP | | Descriptor: | Nucleoprotein, THYMIDINE-5'-TRIPHOSPHATE, ZINC ION | | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | | Deposit date: | 2010-05-06 | | Release date: | 2010-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.983 Å) | | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
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4W9R
 | | Crystal structure of uncharacterised protein Coch_1243 from Capnocytophaga ochracea DSM 7271 | | Descriptor: | ACETATE ION, GLYCEROL, Uncharacterized protein | | Authors: | Chang, C, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-08-27 | | Release date: | 2014-09-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Crystal structure of uncharacterised protein Coch_1243 from Capnocytophaga ochracea DSM 7271
To Be Published
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9EZ8
 | | Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba. | | Descriptor: | 6,7-dimethyl-8-ribityllumazine synthase | | Authors: | Chee, M, Trapani, S, Hoh, F, Lai Kee Him, J, Yvon, M, Blanc, S, Bron, P. | | Deposit date: | 2024-04-11 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba.
To Be Published
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1MKH
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4DQ0
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4E9D
 | | The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with 3-(1-benzothiophen-2-yl)propanoyl-derivatized DPPLHSpTA peptide | | Descriptor: | 3-(1-benzothiophen-2-yl)propanoyl-derivatized DPPLHSpTA peptide, GLYCEROL, Serine/threonine-protein kinase PLK1 | | Authors: | Sledz, P, Hyvonen, M, Lang, S, Stubbs, C.J, Abell, C. | | Deposit date: | 2012-03-21 | | Release date: | 2012-10-10 | | Last modified: | 2012-12-12 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | High-throughput interrogation of ligand binding mode using a fluorescence-based assay.
Angew.Chem.Int.Ed.Engl., 51, 2012
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3CBR
 | | Crystal structure of human Transthyretin (TTR) at pH3.5 | | Descriptor: | Transthyretin | | Authors: | Mohamedmohaideen, N.N, Palaninathan, S.K, Snee, W.C, Kelly, J.W, C Sacchettini, J. | | Deposit date: | 2008-02-22 | | Release date: | 2008-08-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.
J.Mol.Biol., 382, 2008
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2FMT
 | | METHIONYL-TRNAFMET FORMYLTRANSFERASE COMPLEXED WITH FORMYL-METHIONYL-TRNAFMET | | Descriptor: | FORMYL-METHIONYL-TRNAFMET2, MAGNESIUM ION, METHIONYL-TRNA FMET FORMYLTRANSFERASE, ... | | Authors: | Schmitt, E, Mechulam, Y, Blanquet, S. | | Deposit date: | 1998-07-29 | | Release date: | 1999-07-29 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.
EMBO J., 17, 1998
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2R2A
 | | Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis | | Descriptor: | SULFATE ION, Uncharacterized protein | | Authors: | Osipiuk, J, Patterson, S, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-08-24 | | Release date: | 2007-09-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis.
To be Published
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