3FY5
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6BBW
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5ICJ
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![BU of 5icj by Molmil](/molmil-images/mine/5icj) | Crystal structure of the Mycobacterium tuberculosis transcriptional repressor EthR2 in complex with BDM41420 | 分子名称: | 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)butan-1-one, Probable transcriptional regulatory protein | 著者 | Wohlkonig, A, Remaut, H, Tanina, A, Meyer, F, Willand, N, Baulard, A.R, Wintjens, R. | 登録日 | 2016-02-23 | 公開日 | 2017-04-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420. Science, 355, 2017
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1MQX
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![BU of 1mqx by Molmil](/molmil-images/mine/1mqx) | NMR Solution Structure of Type-B Lantibiotics Mersacidin in MeOH/H2O Mixture | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2018-08-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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3HH7
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![BU of 3hh7 by Molmil](/molmil-images/mine/3hh7) | Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra) | 分子名称: | Muscarinic toxin-like protein 3 homolog | 著者 | Roy, A, Zhou, X, Chong, M.Z, D'hoedt, D, Foo, C.S, Rajagopalan, N, Nirthanan, S, Bertrand, D, Sivaraman, J, Kini, R.M. | 登録日 | 2009-05-15 | 公開日 | 2010-01-12 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra) J.Biol.Chem., 285, 2010
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1MQZ
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![BU of 1mqz by Molmil](/molmil-images/mine/1mqz) | NMR solution structure of type-B lantibiotics mersacidin bound to lipid II in DPC micelles | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2018-08-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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1MQY
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![BU of 1mqy by Molmil](/molmil-images/mine/1mqy) | NMR solution structure of type-B lantibiotics mersacidin in DPC micelles | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2018-08-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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6BBT
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![BU of 6bbt by Molmil](/molmil-images/mine/6bbt) | Structure of the major pilin protein (T-13) from Streptococcus pyogenes serotype GAS131465 | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Young, P.G, Baker, E.N, Moreland, N.J. | 登録日 | 2017-10-19 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design. Infect.Immun., 87, 2019
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1TYO
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![BU of 1tyo by Molmil](/molmil-images/mine/1tyo) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix in complex with etheno-NADP | 分子名称: | ETHENO-NADP, isocitrate dehydrogenase | 著者 | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N, Ladenstein, R. | 登録日 | 2004-07-08 | 公開日 | 2005-07-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol., 345, 2005
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3ANU
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![BU of 3anu by Molmil](/molmil-images/mine/3anu) | Crystal structure of D-serine dehydratase from chicken kidney | 分子名称: | CHLORIDE ION, D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Tanaka, H, Senda, M, Venugopalan, N, Yamamoto, A, Senda, T, Ishida, T, Horiike, K. | 登録日 | 2010-09-09 | 公開日 | 2011-06-15 | 最終更新日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney J.Biol.Chem., 286, 2011
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1W9N
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![BU of 1w9n by Molmil](/molmil-images/mine/1w9n) | Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis | 分子名称: | EPILANCIN 15X | 著者 | Ekkelenkamp, M, Hanssen, M.G.M, Hsu, S.-T.D, de Jong, A, Milatovic, D, Verhoef, J, van Nuland, N.A.J. | 登録日 | 2004-10-14 | 公開日 | 2005-04-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis. FEBS Lett., 579, 2005
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3PCI
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![BU of 3pci by Molmil](/molmil-images/mine/3pci) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-IODO-4-HYDROXYBENZOATE | 分子名称: | 3-IODO-4-HYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, FE (III) ION, ... | 著者 | Orville, A.M, Elango, N, Lipscomb, J.D, Ohlendorf, D.H. | 登録日 | 1997-07-02 | 公開日 | 1998-01-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry, 36, 1997
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3PCH
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![BU of 3pch by Molmil](/molmil-images/mine/3pch) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-CHLORO-4-HYDROXYBENZOATE | 分子名称: | 3-CHLORO-4-HYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, FE (III) ION, ... | 著者 | Orville, A.M, Elango, N, Lipscomb, J.D, Ohlendorf, D.H. | 登録日 | 1997-07-01 | 公開日 | 1998-01-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry, 36, 1997
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3C8N
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3PCF
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![BU of 3pcf by Molmil](/molmil-images/mine/3pcf) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-FLURO-4-HYDROXYBENZOATE | 分子名称: | 3-FLUORO-4-HYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, FE (III) ION, ... | 著者 | Orville, A.M, Elango, N, Lipscomb, J.D, Ohlendorf, D.H. | 登録日 | 1997-06-27 | 公開日 | 1998-01-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry, 36, 1997
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3ANV
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![BU of 3anv by Molmil](/molmil-images/mine/3anv) | Crystal structure of D-serine dehydratase from chicken kidney (2,3-DAP complex) | 分子名称: | 3-amino-D-alanine, CHLORIDE ION, D-serine dehydratase, ... | 著者 | Tanaka, H, Senda, M, Venugopalan, N, Yamamoto, A, Senda, T, Ishida, T, Horiike, K. | 登録日 | 2010-09-09 | 公開日 | 2011-06-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney J.Biol.Chem., 286, 2011
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1WCO
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![BU of 1wco by Molmil](/molmil-images/mine/1wco) | The solution structure of the nisin-lipid II complex | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALA-FGA-LYS-DAL-DAL PEPTIDE, ... | 著者 | Hsu, S.-T.D, Breukink, E, Tischenko, E, Lutters, M.A.G, de Kruijff, B, Kaptein, R, Bonvin, A.M.J.J, van Nuland, N.A.J. | 登録日 | 2004-11-19 | 公開日 | 2005-03-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat. Struct. Mol. Biol., 11, 2004
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3B4Y
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![BU of 3b4y by Molmil](/molmil-images/mine/3b4y) | FGD1 (Rv0407) from Mycobacterium tuberculosis | 分子名称: | CITRATE ANION, COENZYME F420, PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 | 著者 | Bashiri, G, Squire, C.J, Moreland, N.M, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2007-10-25 | 公開日 | 2008-04-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding J.Biol.Chem., 283, 2008
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3AWN
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![BU of 3awn by Molmil](/molmil-images/mine/3awn) | Crystal structure of D-serine dehydratase from chicken kidney (EDTA treated) | 分子名称: | D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Tanaka, H, Senda, M, Venugopalan, N, Yamamoto, A, Senda, T, Ishida, T, Horiike, K. | 登録日 | 2011-03-25 | 公開日 | 2011-06-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney. J.Biol.Chem., 286, 2011
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3AWO
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![BU of 3awo by Molmil](/molmil-images/mine/3awo) | Crystal structure of D-serine dehydratase in complex with D-serine from chicken kidney (EDTA-treated) | 分子名称: | D-SERINE, D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Tanaka, H, Senda, M, Venugopalan, N, Yamamoto, A, Senda, T, Ishida, T, Horiike, K. | 登録日 | 2011-03-25 | 公開日 | 2011-06-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney. J.Biol.Chem., 286, 2011
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1XFQ
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![BU of 1xfq by Molmil](/molmil-images/mine/1xfq) | structure of the blue shifted intermediate state of the photoactive yellow protein lacking the N-terminal part | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | 著者 | Bernard, C, Houben, K, Derix, N.M, Marks, D, van der Horst, M.A, Hellingwerf, K.J, Boelens, R, Kaptein, R, van Nuland, N.A. | 登録日 | 2004-09-15 | 公開日 | 2005-08-16 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of a transient photoreceptor intermediate: delta25 photoactive yellow protein STRUCTURE, 13, 2005
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1XGV
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![BU of 1xgv by Molmil](/molmil-images/mine/1xgv) | Isocitrate Dehydrogenase from the hyperthermophile Aeropyrum pernix | 分子名称: | Isocitrate dehydrogenase | 著者 | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | 登録日 | 2004-09-17 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability J.Mol.Biol., 345, 2005
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1XKD
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![BU of 1xkd by Molmil](/molmil-images/mine/1xkd) | Ternary complex of Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix | 分子名称: | CALCIUM ION, ISOCITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Karlstrom, M, Stokke, R, Steen, I.H, Birkeland, N.-K, Ladenstein, R. | 登録日 | 2004-09-28 | 公開日 | 2005-10-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. J.Mol.Biol., 345, 2005
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1XFN
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![BU of 1xfn by Molmil](/molmil-images/mine/1xfn) | NMR structure of the ground state of the photoactive yellow protein lacking the N-terminal part | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | 著者 | Bernard, C, Houben, K, Derix, N.M, Marks, D, van der Horst, M.A, Hellingwerf, K.J, Boelens, R, Kaptein, R, van Nuland, N.A. | 登録日 | 2004-09-15 | 公開日 | 2005-08-16 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of a transient photoreceptor intermediate: delta25 photoactive yellow protein STRUCTURE, 13, 2005
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3Q0V
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![BU of 3q0v by Molmil](/molmil-images/mine/3q0v) | ETHR From mycobacterium tuberculosis in complex with compound bdm31369 | 分子名称: | 4-methyl-1-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}pentan-1-one, HTH-type transcriptional regulator EthR | 著者 | Flipo, M, Desroses, M, Dirie, B, Carette, X, Leroux, F, Lens, Z, Rucktooa, P, Leroux, F, Piveteau, C, Demirkaya, F, Locht, C, Villeret, V, Christophe, T, Jeon, H.K, Brodin, P, Deprez, B, Baulard, A, Willand, N. | 登録日 | 2010-12-16 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, synthesis and optimization of new EthR inhibitors. A new alternative approach to fight tuberculosis by boosting ethionamide To be Published
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