1T3F

THREE DIMENSIONAL STRUCTURE OF A HUMANIZED ANTI-IFN-GAMMA FAB (HuZAF) IN P21 21 21 SPACE GROUP

Summary for 1T3F

• Entry DOI: 10.2210/pdb1t3f/pdb
• Related: 1B2W 1B4J 1T04
• Descriptor: Huzaf antibody light chain, Huzaf antibody heavy chain (3 entities in total)
• Functional Keywords: antibody engineering, humanized and chimeric antibody, fab, gamma-interferon, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 46911.18

Authors

Bourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B. (deposition date: 2004-04-26, release date: 2004-10-05, Last modification date: 2023-08-23)

• Primary citation: Bourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B.; Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms.; Acta Crystallogr.,Sect.D, 60:1761-1769, 2004; PubMed: 15388922; DOI: 10.1107/S0907444904018670

Experimental method

X-RAY DIFFRACTION (2 Å)