4D4U

Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with LewisY tetrasaccharide.

Replaces:  4AH5

Summary for 4D4U

• Entry DOI: 10.2210/pdb4d4u/pdb
• Related: 4D52
• Related PRD ID: PRD_900036 PRD_900124
• Descriptor: FUCOSE-SPECIFIC LECTIN FLEA, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: sugar binding protein
• Biological source: ASPERGILLUS FUMIGATUS
• Total number of polymer chains: 2
• Total formula weight: 74240.58

Authors

Houser, J.,Komarek, J.,Kostlanova, N.,Lahmann, M.,Cioci, G.,Varrot, A.,Imberty, A.,Wimmerova, M. (deposition date: 2014-10-31, release date: 2015-03-11, Last modification date: 2023-12-20)

• Primary citation: Houser, J.,Komarek, J.,Cioci, G.,Varrot, A.,Imberty, A.,Wimmerova, M.; Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.; Acta Crystallogr.,Sect.D, 71:442-, 2015; PubMed: 25760594; DOI: 10.1107/S1399004714026595

Experimental method

X-RAY DIFFRACTION (1.99 Å)