4D4U
Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with LewisY tetrasaccharide.
Replaces: 4AH5Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FUCOSE-SPECIFIC LECTIN FLEA | polymer | 315 | 34628.5 | 2 | UniProt (Q4WW81) Pfam (PF07938) | ASPERGILLUS FUMIGATUS | AFL |
| 2 | C, D, G, H (C, D, G, H) | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 529.5 | 4 | In PDB BIRD (PRD_900036) GlyTouCan (G61459JW) | H type 2 antigen, beta anomer | ||
| 3 | E, F, I (E, F, I) | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | branched | 675.6 | 3 | In PDB BIRD (PRD_900124) GlyTouCan (G82236PZ) | Lewis Y antigen, alpha anomer | ||
| 4 | J (J) | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose | branched | 326.3 | 1 | In PDB GlyTouCan (G00068MO) | |||
| 5 | K, L (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | M, N (A, B) | alpha-L-fucopyranose | non-polymer | 164.2 | 2 | Chemie (FUC) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 412 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 315 (UniProt: Q4WW81)
| PDB | External Database | Details |
|---|---|---|
| Ser 20 | Leu 20 | conflict |
| Cys 111 | Arg 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69256.9 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 4471.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 512.5 | |
| All* | Total formula weight | 74240.6 |
