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PDB: 1191 件
7XV7
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BU of 7xv7 by Molmil
Crystal structure of ZYG11B bound to ORF10 peptide
分子名称: Protein zyg-11 homolog B, SULFATE ION
著者Dong, C, Yan, X, Li, Y.
登録日2022-05-21
公開日2022-06-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into ORF10 recognition by ZYG11B.
Biochem.Biophys.Res.Commun., 616, 2022
7XYV
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BU of 7xyv by Molmil
Crystal structure of ZYG11B bound to SFLH degron
分子名称: Protein zyg-11 homolog B
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYW
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BU of 7xyw by Molmil
Crystal structure of ZYG11B bound to AFLH degron
分子名称: Protein zyg-11 homolog B
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYX
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BU of 7xyx by Molmil
Crystal structure of ZYG11B bound to CFLH degron
分子名称: Protein zyg-11 homolog B
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYS
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BU of 7xys by Molmil
Crystal structure of ZER1 bound to SFLH degron
分子名称: Protein zer-1 homolog
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7XYU
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BU of 7xyu by Molmil
Crystal structure of ZER1 bound to TFLH degron
分子名称: Protein zer-1 homolog
著者Dong, C, Yan, X, Li, Y.
登録日2022-06-02
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献CRL2 ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Nat Commun, 13, 2022
7DNO
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BU of 7dno by Molmil
Characterization of Peptide Ligands Against WDR5 Isolated Using Phage Display Technique
分子名称: CYS-ARG-THR-LEU-PRO-PHE, WD repeat-containing protein 5
著者Cao, J, Cao, D, Xiong, B, Li, Y, Fan, T.
登録日2020-12-10
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5.
Molecules, 26, 2021
6N31
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BU of 6n31 by Molmil
WD repeats of human WDR12
分子名称: Ribosome biogenesis protein WDR12, UNKNOWN ATOM OR ION
著者Halabelian, L, Zeng, H, Tempel, W, Li, Y, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2018-11-14
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献WD repeats of human WDR12
To Be Published
6MEW
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BU of 6mew by Molmil
RFXANK ankyrin repeats in complex with a RFX7 peptide
分子名称: DNA-binding protein RFXANK, RFX7 peptide, UNKNOWN ATOM OR ION
著者Tempel, W, Xu, C, Dong, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2018-09-07
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献RFXANK ankyrin repeats in complex with a RFX7 peptide
to be published
6MB2
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BU of 6mb2 by Molmil
Cryo-EM structure of the PYD filament of AIM2
分子名称: Green fluorescent protein, Interferon-inducible protein AIM2
著者Lu, A, Li, Y, Wu, H.
登録日2018-08-29
公開日2018-09-05
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2.
Cell Discov, 1, 2015
6BZE
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BU of 6bze by Molmil
Cryo-EM structure of BCL10 CARD filament
分子名称: B-cell lymphoma/leukemia 10
著者David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H.
登録日2017-12-23
公開日2018-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3MTN
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BU of 3mtn by Molmil
Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor
分子名称: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ...
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3N3K
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BU of 3n3k by Molmil
The catalytic domain of USP8 in complex with a USP8 specific inhibitor
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2010-05-20
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
7XRB
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BU of 7xrb by Molmil
human STK19 dimer
分子名称: CHLORIDE ION, Isoform 2 of Serine/threonine-protein kinase 19, SULFATE ION
著者Sun, Q, Li, Y.
登録日2022-05-10
公開日2023-06-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献human STK19 dimer
To Be Published
3BZH
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BU of 3bzh by Molmil
Crystal structure of human ubiquitin-conjugating enzyme E2 E1
分子名称: GLYCEROL, Ubiquitin-conjugating enzyme E2 E1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-01-18
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1VEZ
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BU of 1vez by Molmil
Crystal Structure of Peptide Deformylase from Leptospira Interrogans(LiPDF) at pH8.0
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, Peptide deformylase, ...
著者Zhou, Z, Song, X, Li, Y, Gong, W.
登録日2004-04-06
公開日2005-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
2P5W
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BU of 2p5w by Molmil
Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, CALCIUM ION, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-16
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
1HS5
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BU of 1hs5 by Molmil
NMR SOLUTION STRUCTURE OF DESIGNED P53 DIMER
分子名称: CELLULAR TUMOR ANTIGEN P53
著者Davison, T.S, Nie, X, Ma, W, Li, Y, Kay, C, Benchimol, S, Arrowsmith, C.H.
登録日2000-12-22
公開日2001-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and functionality of a designed p53 dimer.
J.Mol.Biol., 307, 2001
2PYE
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BU of 2pye by Molmil
Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-05-16
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2P5E
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BU of 2p5e by Molmil
Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-15
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
6KFT
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BU of 6kft by Molmil
MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
著者Sun, Q, Li, Y.
登録日2019-07-08
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
7MWI
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BU of 7mwi by Molmil
Crystal structure of human BAZ2A
分子名称: Bromodomain adjacent to zinc finger domain protein 2A, UNKNOWN ATOM OR ION
著者Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC)
登録日2021-05-17
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.
J.Biol.Chem., 297, 2021
3DB4
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BU of 3db4 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1
分子名称: E3 ubiquitin-protein ligase UHRF1, SULFATE ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-09-16
最終更新日2012-04-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
3DB3
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BU of 3db3 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide
著者Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-09-16
最終更新日2012-04-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
3FDR
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BU of 3fdr by Molmil
Crystal structure of TDRD2
分子名称: Tudor and KH domain-containing protein
著者Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2008-11-26
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
Proc.Natl.Acad.Sci.USA, 106, 2009

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