Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 272 results

3U8I
DownloadVisualize
BU of 3u8i by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8H
DownloadVisualize
BU of 3u8h by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8D
DownloadVisualize
BU of 3u8d by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3QIW
DownloadVisualize
BU of 3qiw by Molmil
Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ...
Authors:Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3QIU
DownloadVisualize
BU of 3qiu by Molmil
Crystal structure of the 226 TCR in complex with MCC/I-Ek
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ...
Authors:Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3U8B
DownloadVisualize
BU of 3u8b by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3V6I
DownloadVisualize
BU of 3v6i by Molmil
Crystal structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase at 2.25 A resolution
Descriptor: CALCIUM ION, SODIUM ION, V-type ATP synthase subunit E, ...
Authors:Stewart, A.G, Lee, L.K, Donohoe, M, Chaston, J.J, Stock, D.
Deposit date:2011-12-19
Release date:2012-02-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The dynamic stator stalk of rotary ATPases
Nat Commun, 3, 2012
4X0N
DownloadVisualize
BU of 4x0n by Molmil
Porcine pancreatic alpha-amylase in complex with helianthamide, a novel proteinaceous inhibitor
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2014-11-21
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6001 Å)
Cite:Structural Templating and Guided Refolding of the Potent Naturally Occurring Peptide Helianthamide Within the Active Site of Amylase, a Diabetes and Obesity Therapeutic Target
To Be Published
6G8O
DownloadVisualize
BU of 6g8o by Molmil
Solution structure of the cross-linked SAM domain dimer of murine SLy1
Descriptor: SAM and SH3 domain-containing protein 3
Authors:Kukuk, L.K, Dingley, A.J, Koenig, B.W.
Deposit date:2018-04-09
Release date:2019-01-30
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
Sci Rep, 9, 2019
5LQF
DownloadVisualize
BU of 5lqf by Molmil
CDK1/CyclinB1/CKS2 in complex with NU6102
Descriptor: Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, G2/mitotic-specific cyclin-B1, ...
Authors:Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B.J, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E, Newell, D.R, Turner, D.M, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Endicott, J.A, Cano, C.
Deposit date:2016-08-17
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
J. Med. Chem., 60, 2017
4W93
DownloadVisualize
BU of 4w93 by Molmil
Human pancreatic alpha-amylase in complex with montbretin A
Descriptor: CALCIUM ION, CHLORIDE ION, Montbretin A, ...
Authors:Williams, L.K, Caner, S, Brayer, G.D.
Deposit date:2014-08-27
Release date:2015-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.352 Å)
Cite:The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif.
Nat.Chem.Biol., 11, 2015
2GDV
DownloadVisualize
BU of 2gdv by Molmil
Sucrose phosphorylase from BIFIDOBACTERIUM ADOLESCENTIS reacted with sucrose
Descriptor: beta-D-glucopyranose, sucrose phosphorylase
Authors:Skov, L.K, Mirza, O, Gajhede, M, Katsrup, J.S.
Deposit date:2006-03-17
Release date:2006-09-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural rearrangements of Sucrose Phosphorylase from Bifidobacterium adolescentis during sucrose conversion
To be Published
5NEV
DownloadVisualize
BU of 5nev by Molmil
CDK2/Cyclin A in complex with compound 73
Descriptor: 4-[[6-(3-phenylphenyl)-7~{H}-purin-2-yl]amino]benzenesulfonamide, Cyclin-A2, Cyclin-dependent kinase 2
Authors:Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E.M, Newell, D.R, Turner, D, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Cano, G.
Deposit date:2017-03-12
Release date:2017-03-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
J. Med. Chem., 60, 2017
8FR5
DownloadVisualize
BU of 8fr5 by Molmil
Crystal structure of the Human Smacovirus 1 Rep domain
Descriptor: MANGANESE (II) ION, Rep, SODIUM ION
Authors:Limon, L.K, Shi, K, Dao, A, Rugloski, J, Tompkins, K.J, Aihara, H, Gordon, W.R, Evans IIII, R.L.
Deposit date:2023-01-06
Release date:2023-12-27
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:The crystal structure of the human smacovirus 1 Rep domain.
Acta Crystallogr.,Sect.F, 79, 2023
6OQH
DownloadVisualize
BU of 6oqh by Molmil
Solution NMR structure of a quiet outer membrane protein G Nanopore (OmpG mutant: Delta-L6-D215)
Descriptor: Outer membrane protein G
Authors:Sanganna Gari, R.R, Seelheim, P, Liang, B, Tamm, L.K.
Deposit date:2019-04-26
Release date:2019-06-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Quiet Outer Membrane Protein G (OmpG) Nanopore for Biosensing.
ACS Sens, 4, 2019
7K7P
DownloadVisualize
BU of 7k7p by Molmil
Structure of SARS-CoV-2 nonstuctural protein 1
Descriptor: Host translation inhibitor nsp1
Authors:Green, T.J, Petit, C.M, Clark, L.K.
Deposit date:2020-09-23
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure of Nonstructural Protein 1 from SARS-CoV-2.
J.Virol., 95, 2021
7WQU
DownloadVisualize
BU of 7wqu by Molmil
FeoC from Klebsiella pneumoniae
Descriptor: Ferrous iron transport protein B, Probable [Fe-S]-dependent transcriptional repressor
Authors:Hsueh, K.L, Yu, L.K, Hsieh, Y.C, Hsiao, Y.Y, Chen, C.J.
Deposit date:2022-01-26
Release date:2023-02-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4.202 Å)
Cite:FeoC from Klebsiella pneumoniae uses its iron sulfur cluster to regulate the GTPase activity of the ferrous iron channel.
Biochim Biophys Acta Proteins Proteom, 1871, 2023
2QV4
DownloadVisualize
BU of 2qv4 by Molmil
Human pancreatic alpha-amylase complexed with nitrite and acarbose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5R,6S)-4-{[alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl]oxy}-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose, CALCIUM ION, ...
Authors:Williams, L.K, Maurus, R, Brayer, G.D.
Deposit date:2007-08-07
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
2R2J
DownloadVisualize
BU of 2r2j by Molmil
crystal structure of human ERp44
Descriptor: FORMIC ACID, SUCCINIC ACID, Thioredoxin domain-containing protein 4
Authors:Wang, L.K, Li, S.J, Sun, F, Wang, C.C.
Deposit date:2007-08-25
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail.
Embo Rep., 2008
6WDQ
DownloadVisualize
BU of 6wdq by Molmil
IL23/IL23R/IL12Rb1 signaling complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, ...
Authors:Jude, K.M, Ely, L.K, Glassman, C.R, Thomas, C, Spangler, J.B, Lupardus, P.J, Garcia, K.C.
Deposit date:2020-04-01
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
Cell, 184, 2021
6ZM8
DownloadVisualize
BU of 6zm8 by Molmil
Structure of muramidase from Acremonium alcalophilum
Descriptor: muramidase
Authors:Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S.
Deposit date:2020-07-01
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.78 Å)
Cite:Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution.
Plos One, 16, 2021
6ZMV
DownloadVisualize
BU of 6zmv by Molmil
Structure of muramidase from Trichobolus zukalii
Descriptor: GLYCEROL, SULFATE ION, muramidase
Authors:Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S.
Deposit date:2020-07-04
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution.
Plos One, 16, 2021
6X1K
DownloadVisualize
BU of 6x1k by Molmil
Solution NMR structure of de novo designed TMB2.3
Descriptor: De novo designed transmembrane beta-barrel TMB2.3
Authors:Liang, B, Vorobieva, A.A, Chow, C.M, Baker, D, Tamm, L.K.
Deposit date:2020-05-19
Release date:2021-02-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:De novo design of transmembrane beta barrels.
Science, 371, 2021
6L9I
DownloadVisualize
BU of 6l9i by Molmil
Crystal Structure of Lactobacillus farciminis Oxalate Decarboxylase Formate Complex
Descriptor: FORMIC ACID, MANGANESE (II) ION, Oxalate decarboxylase
Authors:Wu, F, Cheng, L.K, Wang, C.Y.
Deposit date:2019-11-10
Release date:2021-01-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal Structure of Lactobacillus farciminis Oxalate Decarboxylase Formate Complex
To Be Published
6NCA
DownloadVisualize
BU of 6nca by Molmil
HLA-A2 (A*02:01) bound to a peptide from the Epstein-Barr virus BRLF1 protein
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Stern, L.J, Selin, L.K, Song, I.Y.
Deposit date:2018-12-11
Release date:2019-10-23
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (3.300001 Å)
Cite:CDR3 alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
Plos Pathog., 15, 2019

222036

數據於2024-07-03公開中

PDB statisticsPDBj update infoContact PDBjnumon