4ZKR
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6ZJH
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![BU of 6zjh by Molmil](/molmil-images/mine/6zjh) | Trehalose transferase from Thermoproteus uzoniensis soaked with trehalose | 分子名称: | GLYCEROL, Trehalose phosphorylase/synthase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-29 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
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4ZQN
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![BU of 4zqn by Molmil](/molmil-images/mine/4zqn) | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor P41 | 分子名称: | 2-chloro-N,N-dimethyl-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]benzamide, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | 著者 | Kim, Y, Makowska-Grzyska, M, Gu, M, Kavitha, M, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-05-10 | 公開日 | 2015-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. Plos One, 10, 2015
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6ZJ7
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![BU of 6zj7 by Molmil](/molmil-images/mine/6zj7) | Trehalose transferase (TreT) from Thermoproteus uzoniensis soaked with Mg | 分子名称: | GLYCEROL, TETRAETHYLENE GLYCOL, THIOCYANATE ION, ... | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-28 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
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7RD6
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![BU of 7rd6 by Molmil](/molmil-images/mine/7rd6) | Structure of the S. cerevisiae P4B ATPase lipid flippase in the E2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Probable phospholipid-transporting ATPase NEO1 | 著者 | Bai, L, Jain, B.K, You, Q, Duan, H.D, Graham, T.R, Li, H. | 登録日 | 2021-07-09 | 公開日 | 2021-09-29 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural basis of the P4B ATPase lipid flippase activity. Nat Commun, 12, 2021
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7RD8
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![BU of 7rd8 by Molmil](/molmil-images/mine/7rd8) | Structure of the S. cerevisiae P4B ATPase lipid flippase in the E1-ATP state | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Probable phospholipid-transporting ATPase NEO1 | 著者 | Bai, L, Jain, B.K, You, Q, Duan, H.D, Graham, T.R, Li, H. | 登録日 | 2021-07-09 | 公開日 | 2021-09-29 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.64 Å) | 主引用文献 | Structural basis of the P4B ATPase lipid flippase activity. Nat Commun, 12, 2021
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7RTM
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![BU of 7rtm by Molmil](/molmil-images/mine/7rtm) | Cryo-EM Structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE (SLC4A8) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | 著者 | Wang, W.G, Tsirulnikov, K, Zhekova, H, Kayik, G, Muhammad-Khan, H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Zhou, Z.H, Pushkin, A, Kurtz, I. | 登録日 | 2021-08-13 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nat Commun, 12, 2021
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6Z1I
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6Z1O
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6YSP
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![BU of 6ysp by Molmil](/molmil-images/mine/6ysp) | Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate | 分子名称: | GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... | 著者 | Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. | 登録日 | 2020-04-23 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
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7RD7
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![BU of 7rd7 by Molmil](/molmil-images/mine/7rd7) | Structure of the S. cerevisiae P4B ATPase lipid flippase in the E2P-transition state | 分子名称: | MAGNESIUM ION, Probable phospholipid-transporting ATPase NEO1, TETRAFLUOROALUMINATE ION | 著者 | Bai, L, Jain, B.K, You, Q, Duan, H.D, Graham, T.R, Li, H. | 登録日 | 2021-07-09 | 公開日 | 2021-09-29 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis of the P4B ATPase lipid flippase activity. Nat Commun, 12, 2021
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6YW9
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![BU of 6yw9 by Molmil](/molmil-images/mine/6yw9) | Arabidopsis aspartate transcarbamoylase mutant F161A complex with PALA | 分子名称: | GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB | 著者 | Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. | 登録日 | 2020-04-29 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
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6YVB
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![BU of 6yvb by Molmil](/molmil-images/mine/6yvb) | Arabidopsis aspartate transcarbamoylase complex with carbamoyl phosphate | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... | 著者 | Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. | 登録日 | 2020-04-28 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.826 Å) | 主引用文献 | Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
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6YSY
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![BU of 6ysy by Molmil](/molmil-images/mine/6ysy) | Skeletal Myosin bound to MPH-220, MgADP-VO4 | 分子名称: | (9~{S})-5-methyl-12-(4-morpholin-4-ylphenyl)-9-oxidanyl-4-thia-2,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),5-trien-8-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Canon, L, Kikuti, C.M, Gyimesi, M, Malnasi-Csizmadia, A, Houdusse, A. | 登録日 | 2020-04-23 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.246 Å) | 主引用文献 | Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness. Cell, 183, 2020
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4Z0V
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![BU of 4z0v by Molmil](/molmil-images/mine/4z0v) | The structure of human PDE12 residues 161-609 | 分子名称: | 2',5'-phosphodiesterase 12, GLYCEROL, MAGNESIUM ION | 著者 | Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. | 登録日 | 2015-03-26 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J.Biol.Chem., 290, 2015
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6YY1
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![BU of 6yy1 by Molmil](/molmil-images/mine/6yy1) | Arabidopsis aspartate transcarbamoylase in apo state | 分子名称: | GLYCEROL, PYRB | 著者 | Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. | 登録日 | 2020-05-04 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
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6YWJ
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![BU of 6ywj by Molmil](/molmil-images/mine/6ywj) | Arabidopsis aspartate transcarbamoylase mutant F161A complex with UMP | 分子名称: | GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE | 著者 | Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. | 登録日 | 2020-04-29 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
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6YYW
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![BU of 6yyw by Molmil](/molmil-images/mine/6yyw) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | 分子名称: | 2-OXOGLUTARIC ACID, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | 登録日 | 2020-05-06 | 公開日 | 2021-03-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase. Chem Sci, 12, 2020
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6YYY
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![BU of 6yyy by Molmil](/molmil-images/mine/6yyy) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 4,4-dimethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | 分子名称: | 2,2-dimethyl-4-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | 登録日 | 2020-05-06 | 公開日 | 2021-03-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase. Chem Sci, 12, 2020
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6Z6Q
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![BU of 6z6q by Molmil](/molmil-images/mine/6z6q) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-ethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | 分子名称: | (3~{R})-3-ethyl-2-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | 登録日 | 2020-05-29 | 公開日 | 2021-03-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase. Chem Sci, 12, 2020
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6Z6R
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![BU of 6z6r by Molmil](/molmil-images/mine/6z6r) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, N-oxalyl-alpha-methylalanine, and factor X substrate peptide fragment(39mer-4Ser) | 分子名称: | Aspartyl/asparaginyl beta-hydroxylase, BROMIDE ION, Coagulation factor X, ... | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | 登録日 | 2020-05-29 | 公開日 | 2021-03-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase. Chem Sci, 12, 2020
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6YYV
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![BU of 6yyv by Molmil](/molmil-images/mine/6yyv) | |
6YYU
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![BU of 6yyu by Molmil](/molmil-images/mine/6yyu) | |
4Z8B
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![BU of 4z8b by Molmil](/molmil-images/mine/4z8b) | crystal structure of a DGL mutant - H51G H131N | 分子名称: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, GLYCEROL, ... | 著者 | Zamora-Caballero, S, Perez, A, Sanz, L, Bravo, J, Calvete, J.J. | 登録日 | 2015-04-08 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | 主引用文献 | Quaternary structure of Dioclea grandiflora lectin assessed by equilibrium sedimentation and crystallographic analysis of recombinant mutants. Febs Lett., 589, 2015
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6YYX
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![BU of 6yyx by Molmil](/molmil-images/mine/6yyx) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-methyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | 分子名称: | (3~{R})-3-methyl-2-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | 登録日 | 2020-05-06 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase Chem Sci, 12, 2021
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