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PDB: 16 件
8GJM
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BU of 8gjm by Molmil
17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H.
登録日2023-03-16
公開日2023-04-05
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2.
J Med Virol, 95, 2023
8GJN
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BU of 8gjn by Molmil
17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 17B10 Fab, Light chain of 17B10 Fab, ...
著者Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H.
登録日2023-03-16
公開日2023-04-05
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2.
J Med Virol, 95, 2023
3BPS
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BU of 3bps by Molmil
PCSK9:EGF-A complex
分子名称: CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9
著者Kwon, H.J.
登録日2007-12-19
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Molecular basis for LDL receptor recognition by PCSK9.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1D5Y
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BU of 1d5y by Molmil
CRYSTAL STRUCTURE OF THE E. COLI ROB TRANSCRIPTION FACTOR IN COMPLEX WITH DNA
分子名称: DNA (5'-D(*AP*CP*TP*TP*TP*GP*AP*CP*AP*TP*TP*CP*AP*GP*TP*GP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*CP*AP*GP*CP*AP*CP*TP*GP*AP*AP*TP*GP*TP*CP*AP*AP*AP*G)-3'), ROB TRANSCRIPTION FACTOR
著者Kwon, H.J, Bennik, M.H.J, Demple, B, Ellenberger, T.
登録日1999-10-12
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA.
Nat.Struct.Biol., 7, 2000
3GKH
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BU of 3gkh by Molmil
NPC1(NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Kwon, H.J.
登録日2009-03-10
公開日2009-07-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.
Cell(Cambridge,Mass.), 137, 2009
3GCW
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BU of 3gcw by Molmil
PCSK9:EGFA(H306Y)
分子名称: CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9
著者Kwon, H.J.
登録日2009-02-22
公開日2009-03-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
J.Biol.Chem., 284, 2009
3GKI
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BU of 3gki by Molmil
NPC1(NTD):cholesterol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Kwon, H.J.
登録日2009-03-10
公開日2009-07-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.
Cell(Cambridge,Mass.), 137, 2009
3GKJ
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NPC1D(NTD):25hydroxycholesterol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25-HYDROXYCHOLESTEROL, ...
著者Kwon, H.J.
登録日2009-03-10
公開日2009-07-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.
Cell(Cambridge,Mass.), 137, 2009
1AE9
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BU of 1ae9 by Molmil
STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE
分子名称: LAMBDA INTEGRASE
著者Kwon, H.J, Tirumalai, R, Landy, A, Ellenberger, T.
登録日1997-03-06
公開日1997-11-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Flexibility in DNA recombination: structure of the lambda integrase catalytic core.
Science, 276, 1997
3QNT
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BU of 3qnt by Molmil
NPC1L1 (NTD) Structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1-like protein 1
著者Kwon, H.J.
登録日2011-02-09
公開日2011-05-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献The Structure of the NPC1L1 N-Terminal Domain in a Closed Conformation.
Plos One, 6, 2011
7TPR
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BU of 7tpr by Molmil
Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants
分子名称: Nanobody 7A3, Nanobody 8A2, Spike glycoprotein
著者Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J.
登録日2022-01-25
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Camel nanobodies broadly neutralize SARS-CoV-2 variants
bioRxiv, 2021
5TH9
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BU of 5th9 by Molmil
Structure determination of a potent, selective antibody inhibitor of human MMP9 (GS-5745 bound to MMP-9)
分子名称: CALCIUM ION, COBALT HEXAMMINE(III), GS-5745 Fab heavy chain, ...
著者Appleby, T.C, Greenstein, A.E, Kwon, H.J.
登録日2016-09-29
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
5TH6
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BU of 5th6 by Molmil
Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9)
分子名称: CALCIUM ION, Matrix metalloproteinase-9,Matrix metalloproteinase-9, ZINC ION
著者Appleby, T.C, Greenstein, A.E, Kwon, H.J.
登録日2016-09-29
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
3GCX
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BU of 3gcx by Molmil
PCSK9:EGFA (pH 7.4)
分子名称: CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9
著者McNutt, M.C, Kwon, H.J, Chen, C, Chen, J.R, Horton, J.D, Lagace, T.A.
登録日2009-02-22
公開日2009-03-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
J.Biol.Chem., 284, 2009
1P7D
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BU of 1p7d by Molmil
Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA
分子名称: 26-MER, 5'-D(*CP*AP*AP*TP*GP*CP*CP*AP*AP*CP*TP*TP*T)-3', Integrase
著者Aihara, H, Kwon, H.J, Nunes-Duby, S.E, Landy, A, Ellenberger, T.
登録日2003-05-01
公開日2003-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Conformational Switch Controls the DNA Cleavage Activity of Lambda Integrase
Mol.Cell, 12, 2003
3ONT
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BU of 3ont by Molmil
The Crystal Structure of Spot14, a modulator of lipogenesis
分子名称: Spot 14 protein
著者Colbert, C.L, Kwon, H.J, Deisenhofer, J.
登録日2010-08-30
公開日2011-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of Spot 14, a modulator of fatty acid synthesis.
Proc.Natl.Acad.Sci.USA, 107, 2010

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件を2024-07-24に公開中

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