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PDB: 74 件
4L7X
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BU of 4l7x by Molmil
Crystal structure of the DIDO PHD finger in complex with H3K4me3
分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
著者Tong, Q, Gatchalian, J, Kutateladze, T.G.
登録日2013-06-14
公開日2013-07-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
6OIE
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BU of 6oie by Molmil
The double PHD finger (DPF) of MORF in complex with histone H3K14cr
分子名称: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2019-04-09
公開日2019-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.075 Å)
主引用文献Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Nat Commun, 10, 2019
8E4V
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BU of 8e4v by Molmil
Solution structure of the WH domain of MORF
分子名称: Isoform 3 of Histone acetyltransferase KAT6B
著者Zhang, Y, Kutateladze, T.G.
登録日2022-08-19
公開日2023-05-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Nat Commun, 14, 2023
7TV0
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BU of 7tv0 by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with dual-acetylated SARS-CoV-2 E
分子名称: Bromodomain-containing protein 4, Envelope small membrane protein
著者Vann, K.R, Holt, T.A, Kutateladze, T.G.
登録日2022-02-03
公開日2022-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
7MJU
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BU of 7mju by Molmil
Crystal structure of human AF10 PZP bound to histone H3 tail
分子名称: Histone H3.1,Protein AF-10, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2021-04-20
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
4L58
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BU of 4l58 by Molmil
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION
著者Tong, Q, Ali, M, Kutateladze, T.G.
登録日2013-06-10
公開日2013-06-26
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Molecular basis for chromatin binding and regulation of MLL5.
Proc.Natl.Acad.Sci.USA, 110, 2013
7TUQ
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BU of 7tuq by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
分子名称: Bromodomain-containing protein 4, Envelope small membrane protein
著者Vann, K.R, Kutateladze, T.G.
登録日2022-02-03
公開日2022-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
3RCP
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BU of 3rcp by Molmil
Crystal structure of the FAPP1 pleckstrin homology domain
分子名称: GLYCEROL, Pleckstrin homology domain-containing family A member 3
著者Roy, S, He, J, Kutateladze, T.G.
登録日2011-03-31
公開日2011-04-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain.
J.Biol.Chem., 286, 2011
5WLE
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BU of 5wle by Molmil
Crystal structure of the PPS PHD finger in complex with H3K4me3
分子名称: H3K4me3 Peptide, Protein partner of snf, isoform A, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2017-07-26
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.
Structure, 25, 2017
5WLF
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BU of 5wlf by Molmil
Crystal structure of the apo PPS PHD finger
分子名称: GLYCEROL, Protein partner of snf, isoform A, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2017-07-26
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.
Structure, 25, 2017
6WXK
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BU of 6wxk by Molmil
PHF23 PHD Domain Apo
分子名称: PHD finger protein 23, ZINC ION
著者Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T.
登録日2020-05-11
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.
Nat Commun, 11, 2020
6O1E
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BU of 6o1e by Molmil
The crystal structure of human MORC3 ATPase-CW in complex with AMPPNP
分子名称: MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Klein, B.J, Zhang, Y, Kutateladze, T.G.
登録日2019-02-19
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Mechanism for autoinhibition and activation of the MORC3 ATPase.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6O7G
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BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
分子名称: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2019-03-07
公開日2019-05-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
6E86
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BU of 6e86 by Molmil
Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide
分子名称: H3K4ac, ZINC ION, ZZ-type zinc finger-containing protein 3
著者Zhang, Y, Kutateladze, T.G.
登録日2018-07-27
公開日2018-09-19
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
6DS6
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BU of 6ds6 by Molmil
Crystal structure of p300 ZZ domain in complex with histone H3 peptide
分子名称: CHLORIDE ION, Histone H3 peptide-Histone acetyltransferase p300 Chimeric protein, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2018-06-13
公開日2018-08-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3.
Nat. Struct. Mol. Biol., 25, 2018
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
分子名称: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-21
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGF
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BU of 3lgf by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2
分子名称: DIMETHYLATED p53 Lysine 370 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGL
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BU of 3lgl by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2
分子名称: DIMETHYLATED p53 LYSINE 382 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
6MIN
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BU of 6min by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIM
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BU of 6mim by Molmil
Crystal structure of AF9 YEATS domain Y78W mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Protein AF-9
著者Vann, K.R, Klein, B.J, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.525 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIO
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BU of 6mio by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr
分子名称: Histone H3K9pr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIQ
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BU of 6miq by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu
分子名称: Histone H3K9bu, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIP
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BU of 6mip by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant
分子名称: DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIL
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BU of 6mil by Molmil
Crystal structure of AF9 YEATS domain in complex with histone H3K9bu
分子名称: DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ...
著者Vann, K.R, Klein, B.J, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
3MDF
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BU of 3mdf by Molmil
Crystal structure of the RRM domain of Cyclophilin 33
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G.
登録日2010-03-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010

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