6VYV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vyv by Molmil](/molmil-images/mine/6vyv) | |
6WDS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wds by Molmil](/molmil-images/mine/6wds) | Enterovirus D68 in complex with human monoclonal antibody EV68-159 | Descriptor: | EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ... | Authors: | Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-04-01 | Release date: | 2020-07-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol, 5, 2020
|
|
6WDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wdt by Molmil](/molmil-images/mine/6wdt) | Enterovirus D68 in complex with human monoclonal antibody EV68-228 | Descriptor: | EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ... | Authors: | Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-04-01 | Release date: | 2020-07-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol, 5, 2020
|
|
7N69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n69 by Molmil](/molmil-images/mine/7n69) | |
7N6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n6a by Molmil](/molmil-images/mine/7n6a) | |
5IRE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ire by Molmil](/molmil-images/mine/5ire) | The cryo-EM structure of Zika Virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein | Authors: | Sirohi, D, Chen, Z, Sun, L, Klose, T, Pierson, T, Rossmann, M, Kuhn, R. | Deposit date: | 2016-03-13 | Release date: | 2016-03-30 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The 3.8 angstrom resolution cryo-EM structure of Zika virus. Science, 352, 2016
|
|
1P58
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p58 by Molmil](/molmil-images/mine/1p58) | Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction | Descriptor: | Envelope protein M, Major envelope protein E | Authors: | Zhang, W, Chipman, P.R, Corver, J, Johnson, P.R, Zhang, Y, Mukhopadhyay, S, Baker, T.S, Strauss, J.H, Rossmann, M.G, Kuhn, R.J. | Deposit date: | 2003-04-25 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus Nat.Struct.Biol., 10, 2003
|
|
3IYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3iya by Molmil](/molmil-images/mine/3iya) | Association of the pr peptides with dengue virus blocks membrane fusion at acidic pH | Descriptor: | Envelope protein, prM protein | Authors: | Yu, I, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G, Chen, J. | Deposit date: | 2009-06-01 | Release date: | 2010-04-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (22 Å) | Cite: | Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion. J.Virol., 83, 2009
|
|
7T9P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t9p by Molmil](/molmil-images/mine/7t9p) | |
7TAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tah by Molmil](/molmil-images/mine/7tah) | |
7TAJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7taj by Molmil](/molmil-images/mine/7taj) | |
7TAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7taf by Molmil](/molmil-images/mine/7taf) | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092 | Descriptor: | N,N-dimethyl-5-(3-{2-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}propyl)-1,2-oxazole-3-carboxamide, viral protein 1, viral protein 2, ... | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-12-20 | Release date: | 2023-01-25 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68 To Be Published
|
|
7TAG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tag by Molmil](/molmil-images/mine/7tag) | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, viral protein 1, viral protein 2, ... | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-12-20 | Release date: | 2023-01-25 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68 To Be Published
|
|
3ZFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zff by Molmil](/molmil-images/mine/3zff) | Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 | Descriptor: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ... | Authors: | Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2012-12-11 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4AED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aed by Molmil](/molmil-images/mine/4aed) | Crystal structure of Human enterovirus 71 | Descriptor: | CALCIUM ION, LAURIC ACID, VP1, ... | Authors: | Plevka, P, Perera, R, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2012-01-09 | Release date: | 2012-04-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal Structure of Human Enterovirus 71. Science, 336, 2012
|
|
7LCG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lcg by Molmil](/molmil-images/mine/7lcg) | The mature Usutu SAAR-1776, Model A | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Khare, B, Klose, T, Fang, Q, Kuhn, R. | Deposit date: | 2021-01-11 | Release date: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7LCH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lch by Molmil](/molmil-images/mine/7lch) | The mature Usutu SAAR-1776, Model B | Descriptor: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Khare, B, Klose, T, Fang, Q, Kuhn, R. | Deposit date: | 2021-01-11 | Release date: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
1Z8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z8y by Molmil](/molmil-images/mine/1z8y) | Mapping the E2 Glycoprotein of Alphaviruses | Descriptor: | Capsid protein C, Spike glycoprotein E1, Spike glycoprotein E2 | Authors: | Mukhopadhyay, S, Zhang, W, Gabler, S, Chipman, P.R, Strauss, E.G, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2005-03-31 | Release date: | 2006-02-07 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses. Structure, 14, 2006
|
|
3ZFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zfe by Molmil](/molmil-images/mine/3zfe) | Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 | Descriptor: | CHLORIDE ION, SODIUM ION, SPHINGOSINE, ... | Authors: | Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2012-12-11 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
2B6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b6b by Molmil](/molmil-images/mine/2b6b) | Cryo EM structure of Dengue complexed with CRD of DC-SIGN | Descriptor: | CD209 antigen, envelope glycoprotein | Authors: | Pokidysheva, E, Zhang, Y, Battisti, A.J, Bator-Kelly, C.M, Chipman, P.R, Gregorio, G, Hendrickson, W.A, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2005-09-30 | Release date: | 2006-03-07 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN Cell(Cambridge,Mass.), 124, 2006
|
|
7V0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v0n by Molmil](/molmil-images/mine/7v0n) | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21 | Descriptor: | IgG 21 Fab heavy chain, IgG 21 Fab light chain, Spike glycoprotein E1, ... | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | Deposit date: | 2022-05-10 | Release date: | 2023-04-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7V0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v0o by Molmil](/molmil-images/mine/7v0o) | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-94 | Descriptor: | IgG 94 Fab heavy chain, IgG 94 Fab light chain, Spike glycoprotein E1, ... | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | Deposit date: | 2022-05-10 | Release date: | 2023-04-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7V0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v0p by Molmil](/molmil-images/mine/7v0p) | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a potently neutralizing human antibody IgG-106 | Descriptor: | IgG 106 Fab heavy chain, IgG 106 Fab light chain, Spike glycoprotein E1, ... | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | Deposit date: | 2022-05-10 | Release date: | 2023-04-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
3ZFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zfg by Molmil](/molmil-images/mine/3zfg) | Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 | Descriptor: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ... | Authors: | Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2012-12-11 | Release date: | 2013-03-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4C0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c0y by Molmil](/molmil-images/mine/4c0y) | Cryo-EM reconstruction of empty enterovirus 71 in complex with a neutralizing antibody E18 | Descriptor: | FAB EV18 4 D6-1 F1 G9, VP1, VP2, ... | Authors: | Plevka, P, Perera, R, Cardosa, J, Suksatu, A, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2013-08-08 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | Neutralizing Antibodies Can Initiate Genome Release from Human Enterovirus 71. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|