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PDB: 27 results

1HN3
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SOLUTION STRUCTURE OF THE N-TERMINAL 37 AMINO ACIDS OF THE MOUSE ARF TUMOR SUPPRESSOR PROTEIN
Descriptor: P19 ARF PROTEIN
Authors:DiGiammarino, E.L, Filippov, I, Weber, J.D, Bothner, B, Kriwacki, R.W.
Deposit date:2000-12-05
Release date:2001-12-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein.
Biochemistry, 40, 2001
3RTR
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BU of 3rtr by Molmil
A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A.
Deposit date:2011-05-03
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
6BF2
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BU of 6bf2 by Molmil
Solution structure of a Bcl-xL S62E mutant
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Phillips, A, Kriwacki, R.W.
Deposit date:2017-10-25
Release date:2017-11-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Regulation of apoptosis by an intrinsically disordered region of Bcl-xL.
Nat. Chem. Biol., 14, 2018
1W9R
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BU of 1w9r by Molmil
Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Descriptor: CHOLINE BINDING PROTEIN A
Authors:Luo, R, Mann, B, Lewis, W.S, Rowe, A, Heath, R, Stewart, M.L, Hamburger, A.E, Bjorkman, P.J, Sivakolundu, S, Lacy, E.R, Tuomanen, E, Kriwacki, R.W.
Deposit date:2004-10-15
Release date:2005-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
4N8M
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BU of 4n8m by Molmil
Structural polymorphism in the N-terminal oligomerization domain of NPM1
Descriptor: COBALT (II) ION, Nucleophosmin
Authors:Mitrea, D, Royappa, G, Buljan, M, Yun, M, Pytel, N, Satumba, J, Nourse, A, Park, C, Babu, M.M, White, S.W, Kriwacki, R.W.
Deposit date:2013-10-17
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural polymorphism in the N-terminal oligomerization domain of NPM1.
Proc.Natl.Acad.Sci.USA, 111, 2014
1I1S
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BU of 1i1s by Molmil
SOLUTION STRUCTURE OF THE TRANSCRIPTIONAL ACTIVATION DOMAIN OF THE BACTERIOPHAGE T4 PROTEIN MOTA
Descriptor: MOTA
Authors:Li, N, Zhang, W, White, S.W, Kriwacki, R.W.
Deposit date:2001-02-02
Release date:2001-02-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA.
Biochemistry, 40, 2001
2DCO
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BU of 2dco by Molmil
S1P4 First Extracellular Loop Peptidomimetic
Descriptor: S1P4 First Extracellular Loop Peptidomimetic
Authors:Pham, T.C.T, Kriwacki, R.W, Parrill, A.L.
Deposit date:2006-01-11
Release date:2007-01-23
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Peptide design and structural characterization of a GPCR loop mimetic
Biopolymers, 86, 2007
3O6B
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BU of 3o6b by Molmil
A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution
Descriptor: Cell division control protein 53, Defective in cullin neddylation protein 1
Authors:Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
Deposit date:2010-07-28
Release date:2010-09-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2U
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S. cerevisiae Ubc12
Descriptor: GLYCEROL, NEDD8-conjugating enzyme UBC12
Authors:Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
Deposit date:2010-07-22
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2P
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A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB)
Descriptor: Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL
Authors:Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
Deposit date:2010-07-22
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.233 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
1SP2
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BU of 1sp2 by Molmil
NMR STRUCTURE OF A ZINC FINGER DOMAIN FROM TRANSCRIPTION FACTOR SP1F2, MINIMIZED AVERAGE STRUCTURE
Descriptor: SP1F2, ZINC ION
Authors:Narayan, V.A, Kriwacki, R.W, Caradonna, J.P.
Deposit date:1996-11-21
Release date:1997-04-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition.
J.Biol.Chem., 272, 1997
1SP1
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BU of 1sp1 by Molmil
NMR STRUCTURE OF A ZINC FINGER DOMAIN FROM TRANSCRIPTION FACTOR SP1F3, MINIMIZED AVERAGE STRUCTURE
Descriptor: SP1F3, ZINC ION
Authors:Narayan, V.A, Kriwacki, R.W, Caradonna, J.P.
Deposit date:1996-11-21
Release date:1997-04-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition.
J.Biol.Chem., 272, 1997
1N17
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BU of 1n17 by Molmil
Structure and Dynamics of Thioguanine-modified Duplex DNA
Descriptor: 5'-D(*GP*CP*TP*AP*AP*GP*(S6G)P*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3'
Authors:Somerville, L, Krynetski, E.Y, Krynetskaia, N.F, Beger, R.D, Zhang, W, Marhefka, C.A, Evans, W.E, Kriwacki, R.W.
Deposit date:2002-10-16
Release date:2002-10-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and dynamics of thioguanine-modified duplex DNA
J.Biol.Chem., 278, 2003
1N14
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Structure and Dynamics of Thioguanine-modified Duplex DNA in Comparison with Unmodified DNA; Structure of Unmodified Duplex DNA
Descriptor: 5'-D(*GP*CP*TP*AP*AP*GP*GP*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3'
Authors:Somerville, L, Krynetski, E.Y, Krynetskaia, N.F, Beger, R.D, Zhang, W, Marhefka, C.A, Evans, W.E, Kriwacki, R.W.
Deposit date:2002-10-16
Release date:2002-10-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and dynamics of thioguanine-modified duplex DNA
J.Biol.Chem., 278, 2003
2JPN
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BU of 2jpn by Molmil
Solution Structure of T4 Bacteriophage Helicase Uvsw.1
Descriptor: ATP-dependent DNA helicase uvsW
Authors:Sivakolundu, S.G, Lee, T, White, S.W, Kriwacki, R.W.
Deposit date:2007-05-17
Release date:2007-07-10
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Crystallographic and NMR Analyses of UvsW and UvsW.1 from Bacteriophage T4
J.Biol.Chem., 282, 2007
2M5B
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BU of 2m5b by Molmil
The NMR structure of the BID-BAK complex
Descriptor: Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB
Authors:Moldoveanu, T, Grace, C.R, Kriwacki, R.W, Green, D.R.
Deposit date:2013-02-19
Release date:2013-04-17
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:BID-induced structural changes in BAK promote apoptosis.
Nat.Struct.Mol.Biol., 20, 2013
2ME8
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BU of 2me8 by Molmil
Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2M03
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BU of 2m03 by Molmil
Solution structure of BCL-xL determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Royappa, G, Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013
2ME9
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BU of 2me9 by Molmil
Solution structure of BCL-xL containing the alpha1-alpha2 disordered loop determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2N0W
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Mdmx-SJ212
Descriptor: 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4
Authors:Grace, C.R, Kriwacki, R.W.
Deposit date:2015-03-17
Release date:2016-01-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
2N06
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Mdmx-298
Descriptor: 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one, Protein Mdm4
Authors:Grace, C.R, Kriwacki, R.W.
Deposit date:2015-03-04
Release date:2016-01-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
2N0U
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Mdmx-057
Descriptor: 4-[(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-1-(3-oxidanylidenepiperazin-1-yl)carbonyl-4,5-dihydroimidazol-2-yl]-3-propan-2-yloxy-benzenecarbonitrile, Protein Mdm4
Authors:Grace, C.R, Kriwacki, R.W.
Deposit date:2015-03-17
Release date:2016-01-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
2M6N
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BU of 2m6n by Molmil
3D solution structure of EMI1 (Early Mitotic Inhibitor 1)
Descriptor: F-box only protein 5, ZINC ION
Authors:Frye, J.J, Brown, N.G, Petzold, G, Watson, E.R, Royappa, G.R, Nourse, A, Jarvis, M, Kriwacki, R.W, Peters, J, Stark, H, Schulman, B.A.
Deposit date:2013-04-06
Release date:2013-05-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat.Struct.Mol.Biol., 20, 2013
2MEJ
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BU of 2mej by Molmil
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Descriptor: Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2M04
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BU of 2m04 by Molmil
Solution structure of BCL-xL in complex with PUMA BH3 peptide
Descriptor: Bcl-2-binding component 3, Bcl-2-like protein 1
Authors:Viacava Follis, A, Royappa, G, Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013

 

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