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PDB: 109 件

4RNC
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Crystal structure of an esterase RhEst1 from Rhodococcus sp. ECU1013
分子名称: Esterase, PHOSPHATE ION
著者Dou, S, Kong, X.D, Xu, J.H, Zhou, J.
登録日2014-10-23
公開日2015-10-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Substrate channel evolution of an esterase for the synthesis of Cilastatin
CATALYSIS SCIENCE AND TECHNOLOGY, 5, 2015
6VU2
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M1214_N1 Fab structure
分子名称: M1214 N1 Fab heavy chain, M1214 N1 Fab light chain
著者Pan, R, Kong, X.
登録日2020-02-14
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27, 2020
1EXZ
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BU of 1exz by Molmil
STRUCTURE OF STEM CELL FACTOR
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, SAMARIUM (III) ION, ...
著者Zhang, Z, Zhang, R, Joachimiak, A, Schlessinger, J, Kong, X.
登録日2000-05-05
公開日2000-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation.
Proc.Natl.Acad.Sci.USA, 97, 2000
2TPR
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BU of 2tpr by Molmil
X-RAY STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA FASCICULATA AT 2.4 ANGSTROMS RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE
著者Kuriyan, J, Kong, X.-P, Krishna, T.S.R.
登録日1991-08-22
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1PRO
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BU of 1pro by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881
分子名称: (5R,6R)-2,4-BIS-(4-HYDROXY-3-METHOXYBENZYL)-1,5-DIBENZYL-3-OXO-6-HYDROXY-1,2,4-TRIAZACYCLOHEPTANE, HIV-1 PROTEASE
著者Park, C.H, Kong, X.P, Dealwis, C.G.
登録日1995-07-18
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
J.Med.Chem., 39, 1996
6VY2
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Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
著者Chan, K.-W, Kong, X.P.
登録日2020-02-25
公開日2020-05-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.86 Å)
主引用文献VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27, 2020
1S4W
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BU of 1s4w by Molmil
NMR structure of the cytoplasmic domain of integrin AIIb in DPC micelles
分子名称: Integrin alpha-IIb
著者Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J.
登録日2004-01-19
公開日2004-03-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004
1S4X
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NMR Structure of the integrin B3 cytoplasmic domain in DPC micelles
分子名称: Integrin beta-3
著者Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J.
登録日2004-01-19
公開日2004-03-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004
4D9L
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BU of 4d9l by Molmil
Fab structure of anti-HIV-1 gp120 V2 mAb 697
分子名称: Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697
著者Pan, R.M, Kong, X.P.
登録日2012-01-11
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
Virology, 427, 2012
8HNZ
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BU of 8hnz by Molmil
Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 6FCWP
分子名称: (3~{S},8~{a}~{S})-3-[(5-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, Cytochrome P450-F5053, ...
著者Ma, B.D, Tian, W, Qu, X, Kong, X.D.
登録日2022-12-09
公開日2023-04-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines.
Angew.Chem.Int.Ed.Engl., 62, 2023
8HO1
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Crystal structure of cytochrome P450 NasF5053 mutant F387G
分子名称: CALCIUM ION, Cytochrome P450-F5053, PROTOPORPHYRIN IX CONTAINING FE
著者Ma, B.D, Tian, W, Qu, X, Kong, X.D.
登録日2022-12-09
公開日2023-04-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines.
Angew.Chem.Int.Ed.Engl., 62, 2023
8HO0
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BU of 8ho0 by Molmil
Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 8FCWP
分子名称: (3~{S},8~{a}~{S})-3-[(7-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, Cytochrome P450-F5053, ...
著者Ma, B.D, Tian, W, Qu, X, Kong, X.D.
登録日2022-12-09
公開日2023-04-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines.
Angew.Chem.Int.Ed.Engl., 62, 2023
8HNY
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Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 5FCWP
分子名称: (3~{S},8~{a}~{S})-3-[(4-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cytochrome P450-F5053, PROTOPORPHYRIN IX CONTAINING FE
著者Ma, B.D, Tian, W, Qu, X, Kong, X.D.
登録日2022-12-09
公開日2023-04-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines.
Angew.Chem.Int.Ed.Engl., 62, 2023
1HXW
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BU of 1hxw by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538
分子名称: HIV-1 PROTEASE, RITONAVIR
著者Park, C.H, Nienaber, V, Kong, X.P.
登録日1997-01-24
公開日1998-02-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
Proc.Natl.Acad.Sci.USA, 92, 1995
3D1F
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BU of 3d1f by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide
分子名称: 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, DI(HYDROXYETHYL)ETHER, DNA polymerase III subunit beta, ...
著者Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
登録日2008-05-05
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D1E
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BU of 3d1e by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide
分子名称: DNA polymerase III subunit beta, decamer from polymerase II C-terminal
著者Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
登録日2008-05-05
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D1G
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BU of 3d1g by Molmil
Structure of a small molecule inhibitor bound to a DNA sliding clamp
分子名称: DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid
著者Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
登録日2008-05-05
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3GBS
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BU of 3gbs by Molmil
Crystal structure of Aspergillus oryzae cutinase
分子名称: Cutinase 1
著者Gosser, Y, Lu, Z, Alemu, G, Li, H, Kong, X, Liu, Z, Montclare, J.
登録日2009-02-20
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and functional studies of Aspergillus oryzae cutinase: enhanced thermostability and hydrolytic activity of synthetic ester and polyester degradation.
J.Am.Chem.Soc., 131, 2009
4ZTO
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BU of 4zto by Molmil
Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region
分子名称: Epitope of rabbit monoclonal antibody R53, RABBIT MONOCLONAL ANTIBODY R53 FAB HEAVY CHAIN, RABBIT MONOCLONAL ANTIBODY R53 FAB LIGHT CHAIN
著者Pan, R, Kong, X.-P.
登録日2015-05-14
公開日2015-08-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding.
Emerg Microbes Infect, 4, 2015
4ZTP
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BU of 4ztp by Molmil
Fab structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region
分子名称: Heavy chain of Fab fragment of rabbit monoclonal antibody R53, Light chain of Fab fragment of rabbit monoclonal antibody R53
著者Pan, R, Kong, X.-P.
登録日2015-05-14
公開日2015-08-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding.
Emerg Microbes Infect, 4, 2015
4YWG
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BU of 4ywg by Molmil
Crystal structure of 830A in complex with V1V2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of anti-HIV-1 gp120 V1V2 antibody 830A, Light chain of anti-HIV-1 gp120 V1V2 antibody 830A, ...
著者Pan, R, Kong, X.
登録日2015-03-20
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel.
J.Virol., 89, 2015
4M1D
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BU of 4m1d by Molmil
Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
分子名称: Cyclic V3 Arch Peptide, Fab mAb 447-52D Heavy Chain, Fab mAb 447-52D Light Chain, ...
著者Killikelly, A, Kong, X.P.
登録日2013-08-02
公開日2013-09-04
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120.
Biochemistry, 52, 2013
4JO4
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Crystal structure of rabbit mAb R20 Fab
分子名称: PENTAETHYLENE GLYCOL, SULFATE ION, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO3
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Crystal structure of rabbit mAb R20 Fab in complex with V3 C-terminus of HIV-1 Consensus B gp120
分子名称: SULFATE ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO1
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Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 JR-FL gp120
分子名称: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.033 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013

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