6UAN
| B-Raf:14-3-3 complex | 分子名称: | 14-3-3 zeta, Serine/threonine-protein kinase B-raf | 著者 | Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J. | 登録日 | 2019-09-11 | 公開日 | 2019-09-25 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Science, 366, 2019
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6AXF
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6AXG
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5WDS
| Choanoflagellate Salpingoeca rosetta Ras with GDP bound | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kondo, Y, Gee, C.L, Kuriyan, J. | 登録日 | 2017-07-05 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife, 6, 2017
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5WDR
| Choanoflagellate Salpingoeca rosetta Ras with GMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras protein, ... | 著者 | Kondo, Y, Gee, C.L, Kuriyan, J. | 登録日 | 2017-07-05 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife, 6, 2017
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4PJO
| Minimal U1 snRNP | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ETHANOL, ... | 著者 | Kondo, Y, Oubridge, C, van Roon, A.M, Nagai, K. | 登録日 | 2014-05-12 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife, 4, 2015
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1WRU
| Structure of central hub elucidated by X-ray analysis of gene product 44; baseplate component of bacteriophage Mu | 分子名称: | 43 kDa tail protein | 著者 | Kondou, Y, Kitazawa, D, Takeda, S, Yamashita, E, Mizuguchi, M, Kawano, K, Tsukihara, T. | 登録日 | 2004-10-27 | 公開日 | 2005-09-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of central hub elucidated by X-ray analysis of gene product 44; baseplate component of bacteriophage Mu To be Published
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2RT8
| Structure of metallo-dna in solution | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*TP*TP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*TP*CP*GP*CP*G)-3'), MERCURY (II) ION | 著者 | Yamaguchi, H, Sebera, J, Kondo, J, Oda, S, Komuro, T, Kawamura, T, Dairaku, T, Kondo, Y, Okamoto, I, Ono, A, Burda, J.V, Kojima, C, Sychrovsky, V, Tanaka, Y. | 登録日 | 2013-06-18 | 公開日 | 2014-03-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of metallo-DNA with consecutive thymine-HgII-thymine base pairs explains positive entropy for the metallo base pair formation. Nucleic Acids Res., 42, 2014
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2RVP
| Solution structure of DNA Containing Metallo-Base-Pair | 分子名称: | DNA (5'-D(*TP*AP*AP*TP*AP*TP*AP*CP*TP*TP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*AP*AP*CP*TP*AP*TP*AP*TP*TP*A)-3'), SILVER ION | 著者 | Dairaku, T, Furuita, K, Sato, H, Sebera, J, Nakashima, K, Kondo, J, Yamanaka, D, Kondo, Y, Okamoto, I, Ono, A, Sychrovsky, V, Kojima, C, Tanaka, Y. | 登録日 | 2016-03-22 | 公開日 | 2016-08-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure Determination of an Ag(I) -Mediated Cytosine-Cytosine Base Pair within DNA Duplex in Solution with (1) H/(15) N/(109) Ag NMR Spectroscopy. Chemistry, 22, 2016
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4TWT
| Human TNFa dimer in complex with the semi-synthetic bicyclic peptide M21 | 分子名称: | (2,4,6-trimethylbenzene-1,3,5-triyl)trimethanol, ALA-CYS-PRO-PRO-CYS-LEU-TRP-GLN-VAL-LEU-CYS-GLY, GLYCEROL, ... | 著者 | Luzi, S, Kondo, Y, Bernard, E, Stadler, L, Winter, G, Holliger, P. | 登録日 | 2014-07-01 | 公開日 | 2015-02-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Subunit disassembly and inhibition of TNF alpha by a semi-synthetic bicyclic peptide. Protein Eng.Des.Sel., 28, 2015
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6K55
| Inactivated mutant (D140A) of Hyperthermophilic GH6 cellobiohydrolase II (HmCel6A) in complex with hexasaccharide | 分子名称: | Glucanase, MAGNESIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Baba, S, Takeda, M, Okuma, J, Hirose, Y, Nishimura, A, Takata, M, Oda, K, Shibata, D, Kondo, Y, Kumasaka, T. | 登録日 | 2019-05-28 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.883 Å) | 主引用文献 | A hyperthermophilic cellobiohydrolase mined from a hot spring metagenomic data To Be Published
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6K53
| A variant of metagenome-derived GH6 cellobiohydrolase, HmCel6A (P88S/L230F/F414S) | 分子名称: | CITRATE ANION, GH6 cellobiohydrolase, HMCEL6A, ... | 著者 | Baba, S, Takeda, M, Okuma, J, Hirose, Y, Nishimura, A, Takata, M, Oda, K, Shibata, D, Kondo, Y, Kumasaka, T. | 登録日 | 2019-05-28 | 公開日 | 2020-06-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | A hyperthermophilic GH6 cellobiohydrolase (HmCel6A) from a hot spring metagenomic data To Be Published
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6K54
| Hyperthermophilic GH6 cellobiohydrolase II (HmCel6A) in complex with trisaccharide | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Baba, S, Takeda, M, Okuma, J, Hirose, Y, Nishimura, A, Takata, M, Oda, K, Shibata, D, Kondo, Y, Kumasaka, T. | 登録日 | 2019-05-28 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Novel hyperthermophilic cellobiohydrolase II isolated from hot spring microbial community To Be Published
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6K52
| Hyperthermophilic GH6 cellobiohydrolase (HmCel6A) from the microbial flora of a Japanese hot spring | 分子名称: | ACETATE ION, CALCIUM ION, GH6 cellobiohydrolase, ... | 著者 | Baba, S, Takeda, M, Okuma, J, Hirose, Y, Nishimura, A, Takata, M, Oda, K, Shibata, D, Kondo, Y, Kumasaka, T. | 登録日 | 2019-05-28 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.68000138 Å) | 主引用文献 | A hyperthermophilic cellobiohydrolase mined from a hot spring metagenomic data To Be Published
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3SI8
| Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... | 著者 | Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. | 登録日 | 2011-06-17 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
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5DZL
| Crystal structure of the protein human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1 | 著者 | Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2015-09-25 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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4P83
| Structure of engineered PyrR protein (PURPLE PyrR) | 分子名称: | Engineered PyrR protein (Purple), URIDINE-5'-MONOPHOSPHATE | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-30 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4P86
| Structure of PyrR protein from Bacillus subtilis with GMP | 分子名称: | Bifunctional protein PyrR, GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-30 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4P3K
| Structure of ancestral PyrR protein (PLUMPyrR) | 分子名称: | Ancestral PyrR protein (Plum), PENTAETHYLENE GLYCOL, SODIUM ION, ... | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-08 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4PKD
| U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2 | 分子名称: | IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ... | 著者 | Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K. | 登録日 | 2014-05-14 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife, 4, 2015
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4P80
| Structure of ancestral PyrR protein (AncGREENPyrR) | 分子名称: | Ancestral PyrR protein (Green), SULFATE ION | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-29 | 公開日 | 2014-12-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4P81
| Structure of ancestral PyrR protein (AncORANGEPyrR) | 分子名称: | Ancestral PyrR protein (Orange), GLYCEROL, SULFATE ION | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-29 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4P84
| Structure of engineered PyrR protein (VIOLET PyrR) | 分子名称: | Bifunctional protein PyrR, GLYCEROL, SULFATE ION | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-30 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4P82
| Structure of PyrR protein from Bacillus subtilis | 分子名称: | Bifunctional protein PyrR, SULFATE ION | 著者 | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | 登録日 | 2014-03-30 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4QXW
| Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2014-07-22 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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