Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 19 件
7JXF
DownloadVisualize
BU of 7jxf by Molmil
E. coli TSase complex with a bi-substrate reaction intermediate diastereomer analog
分子名称: (2S)-2-({4-[({(6S)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE, N-[4-({[(6S)-2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl]methyl}amino)benzene-1-carbonyl]-L-glutamic acid, ...
著者Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A, Moliner, V, Swiderek, K.
登録日2020-08-27
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry, 60, 2021
7JX1
DownloadVisualize
BU of 7jx1 by Molmil
E. coli TSase complex with a bi-substrate reaction intermediate analog
分子名称: (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid, PHOSPHATE ION, ...
著者Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A.
登録日2020-08-26
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry, 60, 2021
3G4A
DownloadVisualize
BU of 3g4a by Molmil
Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2009-02-03
公開日2009-04-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.
Nature, 458, 2009
3G4C
DownloadVisualize
BU of 3g4c by Molmil
Flavine dependant thymidylate syntahse S88C mutant
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2009-02-03
公開日2009-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.
Nature, 458, 2009
6D4B
DownloadVisualize
BU of 6d4b by Molmil
Crystal structure of Candida boidinii formate dehydrogenase V123A mutant complexed with NAD+ and azide
分子名称: AZIDE ION, CHLORIDE ION, Formate dehydrogenase, ...
著者Guo, Q, Ye, H, Gakhar, L, Cheatum, C.M, Kohen, A.
登録日2018-04-17
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase
Acs Catalysis, 2019
6D4C
DownloadVisualize
BU of 6d4c by Molmil
Crystal structure of Candida boidinii formate dehydrogenase V123G mutant complexed with NAD+ and azide
分子名称: AZIDE ION, CHLORIDE ION, Formate dehydrogenase, ...
著者Guo, Q, Ye, H, Gakhar, L, Cheatum, C.M, Kohen, A.
登録日2018-04-17
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase
Acs Catalysis, 2019
5DNA
DownloadVisualize
BU of 5dna by Molmil
Crystal structure of Candida boidinii formate dehydrogenase
分子名称: FORMATE DEHYDROGENASE, SULFATE ION
著者Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A.
登録日2015-09-09
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.
Biochemistry, 55, 2016
5DN9
DownloadVisualize
BU of 5dn9 by Molmil
Crystal structure of Candida boidinii formate dehydrogenase complexed with NAD+ and azide
分子名称: AZIDE ION, CHLORIDE ION, FDH, ...
著者Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A.
登録日2015-09-09
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.
Biochemistry, 55, 2016
4QLF
DownloadVisualize
BU of 4qlf by Molmil
Crystal structure of I14G DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
4QLE
DownloadVisualize
BU of 4qle by Molmil
Crystal structure of I14A DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
4QLG
DownloadVisualize
BU of 4qlg by Molmil
Crystal structure of I14V DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
4GTL
DownloadVisualize
BU of 4gtl by Molmil
T. Maritima FDTS (R174K mutant) with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTD
DownloadVisualize
BU of 4gtd by Molmil
T. Maritima FDTS (E144R mutant) with FAD and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A, Prabhakar, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTC
DownloadVisualize
BU of 4gtc by Molmil
T. Maritima FDTS (E144R mutant) plus FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A, Prabhakar, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GT9
DownloadVisualize
BU of 4gt9 by Molmil
T. Maritima FDTS with FAD, dUMP and Folate.
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTE
DownloadVisualize
BU of 4gte by Molmil
T. Maritima FDTS (E144R mutant) with FAD and Folate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-({4-[(6aR)-3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]phenyl}carbonyl)-L-glutamic acid, Thymidylate synthase thyX
著者Mathews, I.I, Lesley, S.A, Kohen, A, Prabhakar, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTF
DownloadVisualize
BU of 4gtf by Molmil
T. Maritima FDTS (H53A mutant) with FAD, dUMP and Folate
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTA
DownloadVisualize
BU of 4gta by Molmil
T. Maritima FDTS with FAD, dUMP, and Folinic Acid
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTB
DownloadVisualize
BU of 4gtb by Molmil
T. Maritima FDTS with FAD, dUMP, and Raltitrexed.
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Mathews, I.I, Lesley, S.A, Kohen, A.
登録日2012-08-28
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Folate binding site of flavin-dependent thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 109, 2012

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon