3G4A
Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution
Summary for 3G4A
| Entry DOI | 10.2210/pdb3g4a/pdb |
| Descriptor | Thymidylate synthase thyX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
| Functional Keywords | fdts, thyx, s88a mutation, dump complex, fad, flavoprotein, methyltransferase, nucleotide biosynthesis, transferase |
| Biological source | Thermotoga maritima MSB8 |
| Total number of polymer chains | 4 |
| Total formula weight | 114325.65 |
| Authors | Mathews, I.I.,Lesley, S.A.,Kohen, A. (deposition date: 2009-02-03, release date: 2009-04-07, Last modification date: 2023-02-01) |
| Primary citation | Koehn, E.M.,Fleischmann, T.,Conrad, J.A.,Palfey, B.A.,Lesley, S.A.,Mathews, I.I.,Kohen, A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature, 458:919-923, 2009 Cited by PubMed: 19370033DOI: 10.1038/nature07973 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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