3G4C

Flavine dependant thymidylate syntahse S88C mutant

Summary for 3G4C

Entry DOI	10.2210/pdb3g4c/pdb
Descriptor	Thymidylate synthase thyX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	ftds; thyx; s88c mutation; dump complex, fad, flavoprotein, methyltransferase, nucleotide biosynthesis, transferase
Biological source	Thermotoga maritima
Total number of polymer chains	4
Total formula weight	114453.91
Authors	Mathews, I.I.,Lesley, S.A.,Kohen, A. (deposition date: 2009-02-03, release date: 2009-04-14, Last modification date: 2023-09-06)
Primary citation	Koehn, E.M.,Fleischmann, T.,Conrad, J.A.,Palfey, B.A.,Lesley, S.A.,Mathews, I.I.,Kohen, A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature, 458:919-923, 2009 Cited by PubMed: 19370033 DOI: 10.1038/nature07973 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation