3G4C
Flavine dependant thymidylate syntahse S88C mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thymidylate synthase thyX | polymer | 232 | 27519.7 | 4 | UniProt (Q9WYT0) Pfam (PF02511) | Thermotoga maritima | TS, TSase |
| 2 | E, G, J, L (A, B, C, D) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 4 | Chemie (UMP) PubChem (57164254) PubChem (71773959) PubChem (92144438) PubChem (92209480) PubChem (92209481) PubChem (92209482) PubChem (92449733) PubChem (133126534) PubChem (688) PubChem (65063) PubChem (446899) PubChem (446900) | |||
| 3 | F, H, I, K (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 220 (UniProt: Q9WYT0)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Ile -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Cys 88 | Ser 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110079.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4374.9 | |
| All* | Total formula weight | 114453.9 |
