6DDF
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![BU of 6ddf by Molmil](/molmil-images/mine/6ddf) | Mu Opioid Receptor-Gi Protein Complex | 分子名称: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Koehl, A, Hu, H, Maeda, S, Manglik, A, Kobilka, B.K, Skiniotis, G, Weis, W.I. | 登録日 | 2018-05-10 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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6DDE
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![BU of 6dde by Molmil](/molmil-images/mine/6dde) | Mu Opioid Receptor-Gi Protein Complex | 分子名称: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. | 登録日 | 2018-05-10 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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6N4Y
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![BU of 6n4y by Molmil](/molmil-images/mine/6n4y) | Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.262 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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6N4X
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![BU of 6n4x by Molmil](/molmil-images/mine/6n4x) | Metabotropic Glutamate Receptor 5 Apo Form Ligand Binding Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Metabotropic glutamate receptor 5 | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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6N50
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![BU of 6n50 by Molmil](/molmil-images/mine/6n50) | Metabotropic Glutamate Receptor 5 Extracellular Domain in Complex with Nb43 and L-quisqualic acid | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Skiniotis, G, Mathiesen, J.M, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.751 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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6N51
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![BU of 6n51 by Molmil](/molmil-images/mine/6n51) | Metabotropic Glutamate Receptor 5 bound to L-quisqualate and Nb43 | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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6N52
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![BU of 6n52 by Molmil](/molmil-images/mine/6n52) | Metabotropic Glutamate Receptor 5 Apo Form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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5HK2
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![BU of 5hk2 by Molmil](/molmil-images/mine/5hk2) | Human sigma-1 receptor bound to 4-IBP | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, N-(1-benzylpiperidin-4-yl)-4-iodobenzamide, SULFATE ION, ... | 著者 | Schmidt, H.R, Zheng, S, Gurpinar, E.G, Koehl, A, Manglik, A, Kruse, A.C. | 登録日 | 2016-01-13 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the human sigma 1 receptor. Nature, 532, 2016
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5HK1
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![BU of 5hk1 by Molmil](/molmil-images/mine/5hk1) | Human sigma-1 receptor bound to PD144418 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole, SULFATE ION, ... | 著者 | Schmidt, H.R, Zheng, S, Gurpinar, E, Koehl, A, Manglik, A, Kruse, A.C. | 登録日 | 2016-01-13 | 公開日 | 2016-04-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.5051 Å) | 主引用文献 | Crystal structure of the human sigma 1 receptor. Nature, 532, 2016
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4WMG
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![BU of 4wmg by Molmil](/molmil-images/mine/4wmg) | Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A) | 分子名称: | Lysozyme C | 著者 | Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M. | 登録日 | 2014-10-08 | 公開日 | 2015-04-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array. Acta Crystallogr.,Sect.D, 71, 2015
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4O2X
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![BU of 4o2x by Molmil](/molmil-images/mine/4o2x) | Structure of a malarial protein | 分子名称: | Maltose-binding periplasmic protein, ATP-dependent Clp protease adaptor protein ClpS containing protein chimeric construct | 著者 | AhYoung, A.P, Koehl, A, Cascio, D, Egea, P.F. | 登録日 | 2013-12-17 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum. Protein Sci., 25, 2016
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4O32
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![BU of 4o32 by Molmil](/molmil-images/mine/4o32) | Structure of a malarial protein | 分子名称: | CHLORIDE ION, Thioredoxin | 著者 | Egea, P.F, Koehl, A, Peng, M, Cascio, D. | 登録日 | 2013-12-17 | 公開日 | 2014-12-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex. Biochem.Biophys.Res.Commun., 456, 2015
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6EHM
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![BU of 6ehm by Molmil](/molmil-images/mine/6ehm) | Model of the Ebola virus nucleocapsid subunit from recombinant virus-like particles | 分子名称: | Membrane-associated protein VP24, Nucleoprotein | 著者 | Wan, W, Kolesnikova, L, Clarke, M, Koehler, A, Noda, T, Becker, S, Briggs, J.A.G. | 登録日 | 2017-09-13 | 公開日 | 2017-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Structure and assembly of the Ebola virus nucleocapsid. Nature, 551, 2017
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6EHL
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![BU of 6ehl by Molmil](/molmil-images/mine/6ehl) | Model of the Ebola virus nucleoprotein in recombinant nucleocapsid-like assemblies | 分子名称: | Nucleoprotein | 著者 | Wan, W, Kolesnikova, L, Clarke, M, Koehler, A, Noda, T, Becker, S, Briggs, J.A.G. | 登録日 | 2017-09-13 | 公開日 | 2017-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structure and assembly of the Ebola virus nucleocapsid. Nature, 551, 2017
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6HG7
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![BU of 6hg7 by Molmil](/molmil-images/mine/6hg7) | Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP, (POG)4-LKG HRG FTG LQG-POG(4) | 分子名称: | Collagen alpha-1(II) chain, SULFATE ION | 著者 | Gebauer, J.M, Koehler, A, Dietmar, H, Gompert, M, Neundorf, I, Zaucke, F, Koch, M, Baumann, U. | 登録日 | 2018-08-22 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens. Sci Rep, 8, 2018
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4J1R
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![BU of 4j1r by Molmil](/molmil-images/mine/4j1r) | Crystal Structure of GSK3b in complex with inhibitor 15R | 分子名称: | (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ... | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-02-01 | 公開日 | 2013-03-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor To be Published
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4J71
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![BU of 4j71 by Molmil](/molmil-images/mine/4j71) | Crystal Structure of GSK3b in complex with inhibitor 1R | 分子名称: | (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ... | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-02-12 | 公開日 | 2013-03-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor To be Published
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1QQB
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![BU of 1qqb by Molmil](/molmil-images/mine/1qqb) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*TP*CP*GP*AP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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1QP0
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![BU of 1qp0 by Molmil](/molmil-images/mine/1qp0) | PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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1QP4
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![BU of 1qp4 by Molmil](/molmil-images/mine/1qp4) | PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*TP*CP*GP*AP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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1QP7
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![BU of 1qp7 by Molmil](/molmil-images/mine/1qp7) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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1QPZ
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![BU of 1qpz by Molmil](/molmil-images/mine/1qpz) | PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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1QQA
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![BU of 1qqa by Molmil](/molmil-images/mine/1qqa) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*GP*CP*GP*CP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | 著者 | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | 登録日 | 1999-06-01 | 公開日 | 1999-06-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J.Mol.Biol., 291, 1999
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