5HK1
Human sigma-1 receptor bound to PD144418
Summary for 5HK1
Entry DOI | 10.2210/pdb5hk1/pdb |
Descriptor | Sigma non-opioid intracellular receptor 1, 3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole, SULFATE ION, ... (5 entities in total) |
Functional Keywords | sigma-1 receptor, transmembrane receptor, signal transduction, membrane protein |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus inner membrane: Q99720 |
Total number of polymer chains | 3 |
Total formula weight | 81031.44 |
Authors | Schmidt, H.R.,Zheng, S.,Gurpinar, E.,Koehl, A.,Manglik, A.,Kruse, A.C. (deposition date: 2016-01-13, release date: 2016-04-06, Last modification date: 2024-03-06) |
Primary citation | Schmidt, H.R.,Zheng, S.,Gurpinar, E.,Koehl, A.,Manglik, A.,Kruse, A.C. Crystal structure of the human sigma 1 receptor. Nature, 532:527-530, 2016 Cited by PubMed: 27042935DOI: 10.1038/nature17391 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5051 Å) |
Structure validation
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