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6N50

Metabotropic Glutamate Receptor 5 Extracellular Domain in Complex with Nb43 and L-quisqualic acid

Summary for 6N50
Entry DOI10.2210/pdb6n50/pdb
DescriptorMetabotropic glutamate receptor 5, Nanobody 43, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordscell surface receptor, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight217214.99
Authors
Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Chu, M.,Weis, W.I.,Skiniotis, G.,Mathiesen, J.M.,Kobilka, B.K. (deposition date: 2018-11-20, release date: 2019-01-23, Last modification date: 2023-10-11)
Primary citationKoehl, A.,Hu, H.,Feng, D.,Sun, B.,Zhang, Y.,Robertson, M.J.,Chu, M.,Kobilka, T.S.,Laermans, T.,Steyaert, J.,Tarrasch, J.,Dutta, S.,Fonseca, R.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K.
Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566:79-84, 2019
Cited by
PubMed: 30675062
DOI: 10.1038/s41586-019-0881-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.751 Å)
Structure validation

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