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PDB: 11 件
7U23
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BU of 7u23 by Molmil
Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form
分子名称: Insulin-like growth factor 1 receptor, single-chain LCDV-1 viral insulin-like peptide
著者Kirk, N.S, Lawrence, M.C.
登録日2022-02-22
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Nat Commun, 13, 2022
8TAN
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BU of 8tan by Molmil
CryoEM structure of MFRV-VILP bound to IGF1Rzip
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor, ...
著者Kirk, N.S.
登録日2023-06-27
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Mol Metab, 80, 2024
7U6E
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BU of 7u6e by Molmil
Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM462
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IM462, ...
著者Kirk, N.S, Lawrence, M.C.
登録日2022-03-03
公開日2022-10-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Activation of the human insulin receptor by non-insulin-related peptides
Nat Commun, 13, 2022
7U6D
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BU of 7u6d by Molmil
Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM459
分子名称: IM459, Isoform Short of Insulin receptor
著者Kirk, N.S, Lawrence, M.C.
登録日2022-03-03
公開日2022-10-05
実験手法ELECTRON MICROSCOPY (5.03 Å)
主引用文献Activation of the human insulin receptor by non-insulin-related peptides
Nat Commun, 13, 2022
8UYI
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BU of 8uyi by Molmil
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase Pink1, ...
著者Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
登録日2023-11-13
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
8UYF
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BU of 8uyf by Molmil
Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
分子名称: Serine/threonine-protein kinase Pink1, mitochondrial
著者Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
登録日2023-11-13
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
8UYH
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BU of 8uyh by Molmil
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Pink1, ...
著者Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
登録日2023-11-13
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
6VWH
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BU of 6vwh by Molmil
Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
分子名称: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
著者Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
登録日2020-02-19
公開日2020-05-13
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6VWI
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BU of 6vwi by Molmil
Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
著者Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
登録日2020-02-19
公開日2020-05-13
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6VWG
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BU of 6vwg by Molmil
Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
著者Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
登録日2020-02-19
公開日2020-05-13
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6VWJ
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BU of 6vwj by Molmil
Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II
分子名称: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
著者Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
登録日2020-02-19
公開日2020-05-13
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (4.21 Å)
主引用文献How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020

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件を2024-07-10に公開中

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