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PDB: 812 件

5KJY
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Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W.
登録日2016-06-20
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
Biochem. J., 474, 2017
5KJX
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Co-crystal Structure of PKA RI alpha CNB-B domain with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W.
登録日2016-06-20
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
Biochem. J., 474, 2017
5KJZ
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Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W.
登録日2016-06-20
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.347 Å)
主引用文献Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
Biochem. J., 474, 2017
8XH1
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BU of 8xh1 by Molmil
Orthorhombic crystal structure of green fluorescent protein nowGFP at pH 9.0
分子名称: GLYCEROL, nowGFP
著者Kim, C.U, Kim, J.K.
登録日2023-12-16
公開日2024-09-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing.
Acta Crystallogr D Struct Biol, 80, 2024
8XH2
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Orthorhombic crystal structure of green fluorescent protein nowGFP at pH 6.0
分子名称: GLYCEROL, nowGFP
著者Kim, C.U, Kim, J.K.
登録日2023-12-16
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing.
Acta Crystallogr D Struct Biol, 80, 2024
8XH0
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Monoclinic crystal structure of green fluorescent protein nowGFP at pH 4.8
分子名称: GLYCEROL, nowGFP
著者Kim, C.U, Kim, J.K.
登録日2023-12-16
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing.
Acta Crystallogr D Struct Biol, 80, 2024
2B8I
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Crystal Structure and Functional Studies Reveal that PAS Factor from Vibrio vulnificus is a Novel Member of the Saposin-Fold Family
分子名称: PAS factor
著者Lee, J.H, Yang, S.T, Rho, S.H, Im, Y.J, Kim, S.Y, Kim, Y.R, Kim, M.K, Kang, G.B, Kim, J.I, Rhee, J.H, Eom, S.H.
登録日2005-10-07
公開日2006-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and functional studies reveal that PAS factor from Vibrio vulnificus is a novel member of the saposin-fold family
J.Mol.Biol., 355, 2006
3BE2
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Crystal structure of the VEGFR2 kinase domain in complex with a benzamide inhibitor
分子名称: N-{3-[3-(DIMETHYLAMINO)PROPYL]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]BENZAMIDE, Vascular endothelial growth factor receptor 2
著者Whittington, D.A, Kim, J.L, Long, A.M, Gu, Y, Rose, P, Zhao, H.
登録日2007-11-16
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
J.Med.Chem., 51, 2008
7XZ3
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Crystal structure of the Type I-B CRISPR-associated protein, Csh2 from Thermobaculum terrenum
分子名称: CRISPR-associated protein, Csh2 family
著者Seo, P.W, Gu, D.H, Park, S.Y, Kim, J.S.
登録日2022-06-02
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.889 Å)
主引用文献Structural characterization of the type I-B CRISPR Cas7 from Thermobaculum terrenum.
Biochim Biophys Acta Proteins Proteom, 1871, 2023
4TSV
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HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
分子名称: TUMOR NECROSIS FACTOR-ALPHA
著者Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H.
登録日1997-10-29
公開日1998-12-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
J.Biol.Chem., 273, 1998
2WNW
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The crystal structure of SrfJ from salmonella typhimurium
分子名称: ACTIVATED BY TRANSCRIPTION FACTOR SSRB, GLYCEROL, PHOSPHATE ION
著者Kim, Y.-G, Kim, J.-H, Kim, K.-J.
登録日2009-07-20
公開日2010-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Salmonella Enterica Serovar Typhimurium Virulence Factor Srfj, a Glycoside Hydrolase Family Enzyme.
J.Bacteriol., 191, 2009
3UE8
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BU of 3ue8 by Molmil
Kynurenine Aminotransferase II Inhibitors
分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ...
著者Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R.
登録日2011-10-28
公開日2012-02-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett, 3, 2012
6P8I
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N-terminal 5 domains of IGFIIR
分子名称: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Olson, L.J, Dahms, N.M, Kim, J.-J.P.
登録日2019-06-07
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
4FYB
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Structural and functional characterizations of a thioredoxin-fold protein from Helicobacter pylori
分子名称: GLYCEROL, Thiol:disulfide interchange protein (DsbC)
著者Yoon, J.Y, Kim, J, Lee, S.J, Im, H.N, Kim, H.S, Yoon, H, An, D.R, Kim, J.Y, Kim, S, Han, B.W, Suh, S.W.
登録日2012-07-04
公開日2013-05-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and functional characterization of HP0377, a thioredoxin-fold protein from Helicobacter pylori
Acta Crystallogr.,Sect.D, 69, 2013
8W77
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Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
分子名称: Human Consensus Olfactory Receptor OR52c in apo state, receptor only,Soluble cytochrome b562
著者Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
登録日2023-08-30
公開日2023-12-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
4GSQ
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Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
分子名称: CALCIUM ION, GLYCEROL, Probable conserved lipoprotein LPPS
著者Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W.
登録日2012-08-28
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Acta Crystallogr.,Sect.D, 69, 2013
4GSU
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Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable conserved lipoprotein LPPS
著者Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W.
登録日2012-08-28
公開日2013-02-27
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Acta Crystallogr.,Sect.D, 69, 2013
8TOO
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Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12
分子名称: 4C12 heavy chain, 4C12 light chain, Glycoprotein 42
著者Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.
Immunity, 57, 2024
8TNN
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BU of 8tnn by Molmil
Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A10 heavy chain, A10 light chain, ...
著者Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I.
登録日2023-08-02
公開日2024-03-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.
Immunity, 57, 2024
8TNT
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Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 769C2 heavy chain, 769C2 light chain, ...
著者Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I.
登録日2023-08-02
公開日2024-03-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.
Immunity, 57, 2024
5BV6
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PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP
分子名称: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ...
著者Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W.
登録日2015-06-04
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J.Biol.Chem., 291, 2016
4FYC
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Structural and functional characterizations of a thioredoxin-fold protein from Helicobacter pylori
分子名称: TETRAETHYLENE GLYCOL, Thiol:disulfide interchange protein (DsbC)
著者Yoon, J.Y, Kim, J, Lee, S.J, Im, H.N, Kim, H.S, Yoon, H, An, D.R, Kim, J.Y, Kim, S, Han, B.W, Suh, S.W.
登録日2012-07-04
公開日2013-05-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and functional characterization of HP0377, a thioredoxin-fold protein from Helicobacter pylori
Acta Crystallogr.,Sect.D, 69, 2013
2BA2
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Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae
分子名称: Hypothetical UPF0134 protein MPN010
著者Shin, D.H, Kim, J.-S, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2005-10-13
公開日2006-03-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae.
Protein Sci., 15, 2006
4GSR
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Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
分子名称: 2-(ETHYLMERCURI-THIO)-BENZOIC ACID, GLYCEROL, Probable conserved lipoprotein LPPS
著者Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W.
登録日2012-08-28
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Acta Crystallogr.,Sect.D, 69, 2013
5TSW
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BU of 5tsw by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
分子名称: PROTEIN (TUMOR NECROSIS FACTOR-ALPHA)
著者Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H.
登録日1999-04-22
公開日1999-05-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
J.Biol.Chem., 273, 1998

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