8GTI
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
|
|
8X6M
| Crystal Structure of Glycerol Dehydrogenase in the Presence of NAD+ and Glycerol | Descriptor: | GLYCEROL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Park, T, Kang, J.Y, Jin, M, Yang, J, Kim, H, Noh, C, Eom, S.H. | Deposit date: | 2023-11-21 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the octamerization of glycerol dehydrogenase. Plos One, 19, 2024
|
|
6OI5
| Crystal structure of human Sulfide Quinone Oxidoreductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Sulfide:quinone oxidoreductase, mitochondrial | Authors: | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | Deposit date: | 2019-04-08 | Release date: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.811 Å) | Cite: | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation. Cell Chem Biol, 26, 2019
|
|
6OI6
| Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q (sulfide soaked) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Sulfide:quinone oxidoreductase, mitochondrial, ... | Authors: | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | Deposit date: | 2019-04-08 | Release date: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation. Cell Chem Biol, 26, 2019
|
|
6OIB
| Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, HYDROSULFURIC ACID, ... | Authors: | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | Deposit date: | 2019-04-09 | Release date: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation. Cell Chem Biol, 26, 2019
|
|
6OIC
| Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q (sulfite soaked) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, Sulfide:quinone oxidoreductase, ... | Authors: | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | Deposit date: | 2019-04-09 | Release date: | 2020-01-15 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation. Cell Chem Biol, 26, 2019
|
|
1Y4U
| Conformation rearrangement of heat shock protein 90 upon ADP binding | Descriptor: | Chaperone protein htpG | Authors: | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | Deposit date: | 2004-12-01 | Release date: | 2005-04-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding. Structure, 13, 2005
|
|
1Y4S
| Conformation rearrangement of heat shock protein 90 upon ADP binding | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG, MAGNESIUM ION | Authors: | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | Deposit date: | 2004-12-01 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding. Structure, 13, 2005
|
|
4JJT
| The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv | Descriptor: | ACETATE ION, Enoyl-CoA hydratase, GLYCEROL | Authors: | Tan, K, Holowicki, J, Endres, M, Kim, C.-Y, Kim, H, Hung, L.-W, Terwilliger, T.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | Deposit date: | 2013-03-08 | Release date: | 2013-03-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.496 Å) | Cite: | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv To be Published
|
|
8I9Q
| The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | Phosducin-like protein 3, T-complex protein 1 subunit delta | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8IB8
| Human TRiC-PhLP2A-actin complex in the closed state | Descriptor: | ACTB protein (Fragment), Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-09 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.42 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I9U
| Human TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2024-01-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I1U
| Human TRiC-PhLP2A complex in the closed state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-13 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I6J
| The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit gamma | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-28 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
6KRT
| monodehydroascorbate reductase, MDHAR, from Antarctic hairgrass Deschampsia antarctica | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, monodehydroascorbate reductase | Authors: | Park, A.K, Do, H, Lee, J.H, Kim, H, Choi, W, Kim, I.S, Kim, H.W. | Deposit date: | 2019-08-22 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | monodehydroascorbate reductase, MDHAR, from Antarctic hairgrass Deschampsia antarctica To Be Published
|
|
5V7I
| Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | Descriptor: | (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. | Deposit date: | 2017-03-20 | Release date: | 2017-10-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4GCV
| |
2AD5
| Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | Deposit date: | 2005-07-19 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,). Biochemistry, 44, 2005
|
|
3P28
| |
7V8U
| Crystal structure of PsEst3 wild-type | Descriptor: | Esterase, NITROBENZENE, SULFATE ION | Authors: | Son, J, Kim, H, Kim, H.W. | Deposit date: | 2021-08-23 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4. Iucrj, 10, 2023
|
|
7V8V
| Crystal structure of PsEst3 S128A mutant | Descriptor: | esterase | Authors: | Son, J, Kim, H, Kim, H.W. | Deposit date: | 2021-08-23 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4. Iucrj, 10, 2023
|
|
7V8X
| |
7V8W
| Crystal structure of PsEst3 S128A variant complexed with malonate | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MALONIC ACID, ... | Authors: | Son, J, Kim, H, Kim, H.W. | Deposit date: | 2021-08-23 | Release date: | 2022-08-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4. Iucrj, 10, 2023
|
|
4ZG0
| Crystal structure of Mouse Syndesmos protein | Descriptor: | Protein syndesmos | Authors: | Lee, I, Kim, H, Yoo, J, Cho, H, Lee, W. | Deposit date: | 2015-04-22 | Release date: | 2016-04-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan Biochem.Biophys.Res.Commun., 463, 2015
|
|
5X9Q
| Crystal structure of HldC from Burkholderia pseudomallei | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative cytidylyltransferase | Authors: | Park, J, Kim, H, Kim, S, Lee, D, Shin, D.H. | Deposit date: | 2017-03-08 | Release date: | 2017-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of D-glycero-Beta-D-manno-heptose-1-phosphate adenylyltransferase from Burkholderia pseudomallei. Proteins, 86, 2018
|
|