8GTM
 
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | | 分子名称: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | | 著者 | Cho, H.S, Kim, H. | | 登録日 | 2022-09-08 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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8YBE
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6KF4
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | 著者 | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | 登録日 | 2019-07-06 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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8KHO
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two Cobalt ions and Methionine | | 分子名称: | COBALT (II) ION, METHIONINE, Methionine aminopeptidase 1D, ... | | 著者 | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | 登録日 | 2023-08-22 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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8KHN
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two cobalt ions | | 分子名称: | COBALT (II) ION, Methionine aminopeptidase 1D, mitochondrial, ... | | 著者 | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | 登録日 | 2023-08-22 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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8KHM
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in the unbound form | | 分子名称: | GLYCEROL, Methionine aminopeptidase 1D, mitochondrial, ... | | 著者 | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | 登録日 | 2023-08-22 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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8X6M
 | | Crystal Structure of Glycerol Dehydrogenase in the Presence of NAD+ and Glycerol | | 分子名称: | GLYCEROL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Park, T, Kang, J.Y, Jin, M, Yang, J, Kim, H, Noh, C, Eom, S.H. | | 登録日 | 2023-11-21 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the octamerization of glycerol dehydrogenase.
Plos One, 19, 2024
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7FEQ
 | | Cryo-EM structure of apo BsClpP at pH 6.5 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit | | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | | 登録日 | 2021-07-21 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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7FES
 | | Cryo-EM structure of apo BsClpP at pH 4.2 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit | | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | | 登録日 | 2021-07-21 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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7FER
 | | Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2 | | 分子名称: | ADEP1, ATP-dependent Clp protease proteolytic subunit | | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | | 登録日 | 2021-07-21 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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7FEP
 | | Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5 | | 分子名称: | ADEP1, ATP-dependent Clp protease proteolytic subunit | | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | | 登録日 | 2021-07-21 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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4JJT
 | | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv | | 分子名称: | ACETATE ION, Enoyl-CoA hydratase, GLYCEROL | | 著者 | Tan, K, Holowicki, J, Endres, M, Kim, C.-Y, Kim, H, Hung, L.-W, Terwilliger, T.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | 登録日 | 2013-03-08 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.496 Å) | | 主引用文献 | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv
To be Published
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6OI6
 | | Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q (sulfide soaked) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Sulfide:quinone oxidoreductase, mitochondrial, ... | | 著者 | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | | 登録日 | 2019-04-08 | | 公開日 | 2020-01-15 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.
Cell Chem Biol, 26, 2019
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6OIB
 | | Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, HYDROSULFURIC ACID, ... | | 著者 | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | | 登録日 | 2019-04-09 | | 公開日 | 2020-01-15 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.
Cell Chem Biol, 26, 2019
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6OIC
 | | Crystal structure of human Sulfide Quinone Oxidoreductase in complex with coenzyme Q (sulfite soaked) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, Sulfide:quinone oxidoreductase, ... | | 著者 | Banerjee, R, Cho, U.S, Kim, H, Moon, S. | | 登録日 | 2019-04-09 | | 公開日 | 2020-01-15 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | A Catalytic Trisulfide in Human Sulfide Quinone Oxidoreductase Catalyzes Coenzyme A Persulfide Synthesis and Inhibits Butyrate Oxidation.
Cell Chem Biol, 26, 2019
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6LHU
 | | High resolution structure of FANCA C-terminal domain (CTD) | | 分子名称: | Fanconi anemia complementation group A | | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
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6LHW
 | | Structure of N-terminal and C-terminal domains of FANCA | | 分子名称: | Fanconi anemia complementation group A | | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
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6LHV
 | | Structure of FANCA and FANCG Complex | | 分子名称: | Fanconi anemia complementation group A, Fanconi anemia complementation group G | | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.59 Å) | | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
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4XYH
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4XYI
 | | Mis16 with H4 peptide | | 分子名称: | Histone H4, Kinetochore protein Mis16 | | 著者 | An, S, Kim, H, Cho, U.-S. | | 登録日 | 2015-02-02 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp.
J.Mol.Biol., 427, 2015
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1Y4S
 | | Conformation rearrangement of heat shock protein 90 upon ADP binding | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG, MAGNESIUM ION | | 著者 | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | | 登録日 | 2004-12-01 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
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1Y4U
 | | Conformation rearrangement of heat shock protein 90 upon ADP binding | | 分子名称: | Chaperone protein htpG | | 著者 | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | | 登録日 | 2004-12-01 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
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3P28
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5V7I
 | | Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | | 分子名称: | (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. | | 登録日 | 2017-03-20 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1A77
 | | FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII | | 分子名称: | FLAP ENDONUCLEASE-1 PROTEIN, MAGNESIUM ION | | 著者 | Hwang, K.Y, Baek, K, Kim, H, Cho, Y. | | 登録日 | 1998-03-20 | | 公開日 | 1999-08-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.
Nat.Struct.Biol., 5, 1998
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