5XNW
 
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6K1R
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8BUZ
 | | Structure of Adenylyl cyclase 8 bound to stimulatory G-protein, Ca2+/Calmodulin, Forskolin and MANT-GTP | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ... | | Authors: | Khanppnavar, B, Korkhov, V.M, Mehta, V. | | Deposit date: | 2022-12-01 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
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8BV5
 | | Focus refinement of soluble domain of Adenylyl cyclase 8 bound to stimulatory G protein, Forskolin, ATPalphaS, and Ca2+/Calmodulin in lipid nanodisc conditions | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ... | | Authors: | Khanppnavar, B, Korkhov, V.M. | | Deposit date: | 2023-01-04 | | Release date: | 2024-01-17 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
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5ZIK
 | | Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa | | Descriptor: | GLYCEROL, Probable 2-dehydropantoate 2-reductase, SULFATE ION | | Authors: | Khanppnavar, B, Datta, S. | | Deposit date: | 2018-03-16 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Genome-wide survey and crystallographic analysis suggests a role for both horizontal gene transfer and duplication in pantothenate biosynthesis pathways.
Biochim Biophys Acta Gen Subj, 1863, 2019
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5ZIX
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8PNU
 | | Cryo-EM structure of styrene oxide isomerase bound to benzylamine inhibitor | | Descriptor: | BENZYLAMINE, Nanobody, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Khanppnavar, B, Korkhov, V, Li, X. | | Deposit date: | 2023-07-02 | | Release date: | 2024-04-03 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.12 Å) | | Cite: | Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase.
Nat.Chem., 16, 2024
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7ZH0
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9F25
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8PNV
 | | Cryo-EM structure of styrene oxide isomerase | | Descriptor: | Nanobody, PROTOPORPHYRIN IX CONTAINING FE, Styrene oxide isomerase | | Authors: | Khanppnavar, B, Korkhov, B, Li, X. | | Deposit date: | 2023-07-02 | | Release date: | 2024-04-03 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.048 Å) | | Cite: | Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase.
Nat.Chem., 16, 2024
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7YZ9
 | | Structure of catalytic domain of Rv1625c bound to nanobody NB4 | | Descriptor: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, GLYCEROL, ... | | Authors: | Khanppnavar, B, Mehta, V.J, Iype, T, Korkhov, V.M. | | Deposit date: | 2022-02-19 | | Release date: | 2022-08-31 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
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7ZH6
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7ZHA
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9F2J
 | | Cryo-EM structure of SV2B-BoNT/A1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ... | | Authors: | Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R. | | Deposit date: | 2024-04-23 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
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9F2B
 | | Focused refinement of SV2B luminal domain and BoNT/A1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ... | | Authors: | Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R. | | Deposit date: | 2024-04-22 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
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9F2Y
 | | Focused refinement of SV2B-LD-BoNT/A1 at pH 5.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ... | | Authors: | Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R. | | Deposit date: | 2024-04-24 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (4.39 Å) | | Cite: | Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
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9F3C
 | | Low-resolution (5.4 angstrom) cryo-EM structure of SV2B-BoNT/A1 at pH 5.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2B, ... | | Authors: | Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R. | | Deposit date: | 2024-04-25 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (5.41 Å) | | Cite: | Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
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9F1R
 | | Cryo-EM structure of SV2B-Hc-A1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin A heavy chain, ... | | Authors: | Khanppnavar, B, Leka, O, Korkhov, V, Kammerer, R. | | Deposit date: | 2024-04-20 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Cryo-EM structure of the botulinum neurotoxin A/SV2B complex and its implications for translocation.
Nat Commun, 16, 2025
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8JPS
 | | Structure of Duffy Antigen Receptor for Chemokines (DARC)/ACKR1 in complex with the chemokine, CCL7 (Composite map) | | Descriptor: | Atypical chemokine receptor 1, C-C motif chemokine 7 | | Authors: | Banerjee, R, Khanppnavar, B, Maharana, J, Saha, S, Korkhov, V.M, Shukla, A.K. | | Deposit date: | 2023-06-12 | | Release date: | 2024-07-31 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor.
Cell, 187, 2024
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7YZK
 | | Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya | | Descriptor: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... | | Authors: | Mehta, V, Khanppnavar, B, Korkhov, V.M. | | Deposit date: | 2022-02-20 | | Release date: | 2022-08-31 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
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7YZI
 | | Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya | | Descriptor: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... | | Authors: | Mehta, V, Khanppnavar, B, Korkhov, V.M. | | Deposit date: | 2022-02-20 | | Release date: | 2022-10-05 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.83 Å) | | Cite: | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
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