7YZI

Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya

Summary for 7YZI

• Entry DOI: 10.2210/pdb7yzi/pdb
• EMDB information: 14388
• Descriptor: Adenylate cyclase, Nanobody Nb4, 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: adenylyl cyclase, membrane protein, cyclic adenosine monophosphate, signal transduction, nanobody
• Biological source: Mycobacterium tuberculosis '98-R604 INH-RIF-EM'; More
• Total number of polymer chains: 5
• Total formula weight: 143619.17

Authors

Mehta, V.,Khanppnavar, B.,Korkhov, V.M. (deposition date: 2022-02-20, release date: 2022-10-05)

• Primary citation: Mehta, V.,Khanppnavar, B.,Schuster, D.,Kantarci, I.,Vercellino, I.,Kosturanova, A.,Iype, T.,Stefanic, S.,Picotti, P.,Korkhov, V.M.; Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.; Elife, 11:-, 2022; PubMed: 35980026; DOI: 10.7554/eLife.77032

Experimental method

ELECTRON MICROSCOPY (3.83 Å)