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PDB: 117 results

8SS7
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BU of 8ss7 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
Authors:Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS6
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BU of 8ss6 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
Authors:Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS2
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BU of 8ss2 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, Digitonin, ...
Authors:Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS9
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BU of 8ss9 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
Authors:Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
5H92
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BU of 5h92 by Molmil
Crystal structure of the complex between maize Sulfite Reductase and ferredoxin in the form-3 crystal
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, chloroplastic, ...
Authors:Kurisu, G, Nakayama, M, Hase, T.
Deposit date:2015-12-25
Release date:2016-04-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
6K0M
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BU of 6k0m by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11
Descriptor: Alpha-1,3-glucanase, CALCIUM ION, GLYCEROL, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
6K0Q
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BU of 6k0q by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase D1068A in complex with nigerose
Descriptor: ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.564 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
5H8V
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BU of 5h8v by Molmil
Crystal structure of the complex between maize Sulfite Reductase and ferredoxin in the form-1 crystal
Descriptor: IRON/SULFUR CLUSTER, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Kurisu, G, Nakayama, M, Hase, T.
Deposit date:2015-12-24
Release date:2016-04-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
6K0P
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BU of 6k0p by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase D1045A in complex with nigerose
Descriptor: ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.424 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
6K0N
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BU of 6k0n by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase in complex with nigerose
Descriptor: ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
7C7D
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BU of 7c7d by Molmil
Crystal structure of the catalytic unit of thermostable GH87 alpha-1,3-glucanase from Streptomyces thermodiastaticus strain HF3-3
Descriptor: CALCIUM ION, PENTAETHYLENE GLYCOL, alpha-1,3-glucanase
Authors:Itoh, T, Panti, N, Toyotake, Y, Hayashi, J, Suyotha, W, Yano, S, Wakayama, M, Hibi, T.
Deposit date:2020-05-25
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Crystal structure of the catalytic unit of thermostable GH87 alpha-1,3-glucanase from Streptomyces thermodiastaticus strain HF3-3.
Biochem.Biophys.Res.Commun., 533, 2020
6DM0
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BU of 6dm0 by Molmil
Open state GluA2 in complex with STZ and blocked by IEM-1460, after micelle signal subtraction
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ...
Authors:Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I.
Deposit date:2018-06-04
Release date:2018-08-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
6K0S
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BU of 6k0s by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase D1069A in complex with nigerose
Descriptor: ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.534 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
6DM1
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BU of 6dm1 by Molmil
Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ...
Authors:Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I.
Deposit date:2018-06-04
Release date:2018-08-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
6K0V
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BU of 6k0v by Molmil
Catalytic domain of GH87 alpha-1,3-glucanase D1069A in complex with tetrasaccharides
Descriptor: Alpha-1,3-glucanase, CALCIUM ION, SULFATE ION, ...
Authors:Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
Deposit date:2019-05-07
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
1UFW
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BU of 1ufw by Molmil
Solution structure of RNP domain in Synaptojanin 2
Descriptor: Synaptojanin 2
Authors:He, F, Muto, Y, Ushikoshi, R, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-10
Release date:2003-12-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of RNP domain in Synaptojanin 2
To be Published
1Y88
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BU of 1y88 by Molmil
Crystal Structure of Protein of Unknown Function AF1548
Descriptor: CHLORIDE ION, Hypothetical protein AF1548, SULFATE ION
Authors:Lunin, V.V, Evdokimova, E, Kudritskaya, M, Cuff, M.E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-12-10
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of hypothetical protein AF1548 from Archaeoglobus fulgidus
To be Published
8SS4
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BU of 8ss4 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, Protein cornichon homolog 2, ...
Authors:Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS5
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BU of 8ss5 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, SODIUM ION
Authors:Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2023-05-08
Release date:2023-09-06
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
5VHY
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BU of 5vhy by Molmil
GluA2-2xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHX
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BU of 5vhx by Molmil
GluA2-1xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5IWT
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BU of 5iwt by Molmil
Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6
Authors:Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2016-03-22
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
5IWK
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BU of 5iwk by Molmil
Structure of Transient Receptor Potential (TRP) channel TRPV6
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
Authors:Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2016-03-22
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.247 Å)
Cite:Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
5KBS
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BU of 5kbs by Molmil
Cryo-EM structure of GluA2-0xSTZ at 8.7 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2016-06-03
Release date:2016-07-13
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
5KBU
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BU of 5kbu by Molmil
Cryo-EM structure of GluA2-2xSTZ complex at 7.8 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2016-06-03
Release date:2016-07-13
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016

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