2YCH
 
 | | PilM-PilN type IV pilus biogenesis complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, COMPETENCE PROTEIN PILM, COMPETENCE PROTEIN PILN, ... | | Authors: | Karuppiah, V, Derrick, J.P. | | Deposit date: | 2011-03-15 | | Release date: | 2011-05-11 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the Pilm-Piln Inner Membrane Type Iv Pilus Biogenesis Complex from Thermus Thermophilus.
J.Biol.Chem., 286, 2011
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9GV6
 | | Structure of TCR in complex with peptide-HLA | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Peptide, ... | | Authors: | Karuppiah, V. | | Deposit date: | 2024-09-23 | | Release date: | 2025-04-23 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Determining T-cell receptor binding orientation and Peptide-HLA interactions using cross-linking mass spectrometry.
J.Biol.Chem., 301, 2025
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5FL3
 | | PilT2 from Thermus thermophilus | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Karuppiah, V, Derrick, J.P. | | Deposit date: | 2015-10-21 | | Release date: | 2015-11-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Pilt2 from Thermus Thermophilus
To be Published
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6GW3
 | | Structure of TKS from Cannabis sativa in complex with CoA | | Descriptor: | 3,5,7-trioxododecanoyl-CoA synthase, 3,5,7-trioxododecanoyl-CoA synthase,3,5,7-trioxododecanoyl-CoA synthase, COENZYME A, ... | | Authors: | Karuppiah, V, Leys, D. | | Deposit date: | 2018-06-21 | | Release date: | 2019-10-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structure of a PKS class III from Cannabis sativa
To Be Published
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9HI7
 | | Structure of MC.7.G5 T cell receptor in complex with MR1 R9H | | Descriptor: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, T cell receptor alpha chain MC.7.G5, ... | | Authors: | Karuppiah, V. | | Deposit date: | 2024-11-24 | | Release date: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Molecular basis underpinning MR1 allomorph recognition by an MR1-restricted T cell receptor.
Front Immunol, 16, 2025
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9GV7
 | | Structure of reverse docking TCR in complex with peptide-HLA | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | | Authors: | Karuppiah, V. | | Deposit date: | 2024-09-23 | | Release date: | 2025-04-23 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Determining T-cell receptor binding orientation and Peptide-HLA interactions using cross-linking mass spectrometry.
J.Biol.Chem., 301, 2025
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2WHN
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4BHQ
 | | Structure of the periplasmic domain of the PilN type IV pilus biogenesis protein from Thermus thermophilus | | Descriptor: | COMPETENCE PROTEIN PILN, MAGNESIUM ION | | Authors: | Karuppiah, V, Collins, R.F, Gao, Y, Thistlethwaite, A, Derrick, J.P. | | Deposit date: | 2013-04-05 | | Release date: | 2013-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure and Assembly of an Inner Membrane Platform for Initiation of Type Iv Pilus Biogenesis
Proc.Natl.Acad.Sci.USA, 110, 2013
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7ZT2
 | | Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU | | Descriptor: | 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ... | | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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7ZT4
 | | Structure of E8 TCR in complex with human MR1 bound to 6FP | | Descriptor: | 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | | Authors: | Karuppiah, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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7ZT9
 | | Structure of E8 TCR in complex in human MR1 bound to 4FBA | | Descriptor: | 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ... | | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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7ZT8
 | | Structure of E8 TCR in complex in human MR1 bound to 3FBA | | Descriptor: | 1,2-ETHANEDIOL, 3-methylbenzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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7ZT3
 | | Structure of E8 TCR in complex in human MR1 K43A | | Descriptor: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ... | | Authors: | Karuppiah, V, Srikannathasan, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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6QVI
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7ZT5
 | | Structure of E8 TCR in complex in human MR1 bound to 3FSA | | Descriptor: | 3-methanoyl-2-oxidanyl-benzoic acid, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | | Authors: | Karuppiah, V, Robinson, R.A. | | Deposit date: | 2022-05-09 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
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7ZT7
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8RYN
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8RYQ
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8RYM
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8RYO
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8RYP
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6ERA
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6ER9
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5G24
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4BHR
 | | Structure of the TTHA1221 type IV pilin protein from Thermus thermophilus | | Descriptor: | PILIN, TYPE IV, SULFATE ION | | Authors: | Karuppiah, V, Collins, R.F, Gao, Y, Thistlethwaite, A, Derrick, J.P. | | Deposit date: | 2013-04-05 | | Release date: | 2013-11-20 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and Assembly of an Inner Membrane Platform for Initiation of Type Iv Pilus Biogenesis
Proc.Natl.Acad.Sci.USA, 110, 2013
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