3GLT
| Crystal Structure of Human SIRT3 with ADPR bound to the AceCS2 peptide containing a thioacetyl lysine | Descriptor: | Acetyl-coenzyme A synthetase 2-like, mitochondrial, CARBONATE ION, ... | Authors: | Jin, L, Wei, W, Jiang, Y, Peng, H, Cai, J, Mao, C, Dai, H, Bemis, J.E, Jirousek, M.R, Milne, J.C, Westphal, C.H, Perni, R.B. | Deposit date: | 2009-03-12 | Release date: | 2009-06-16 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284, 2009
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7SAS
| Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | Authors: | Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2021-09-23 | Release date: | 2022-03-09 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022
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7SAQ
| Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | Authors: | Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2021-09-23 | Release date: | 2022-03-09 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022
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7SAR
| Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | Authors: | Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2021-09-23 | Release date: | 2022-03-09 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022
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2Q67
| Crystal Structure of Nak channel D66A mutant | Descriptor: | CALCIUM ION, Potassium channel protein, SODIUM ION | Authors: | Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2007-06-04 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2Q6A
| Crystal Structure of Nak channel D66E mutant | Descriptor: | CALCIUM ION, Potassium channel protein, SODIUM ION | Authors: | Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2007-06-04 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3GLU
| Crystal Structure of Human SIRT3 with AceCS2 peptide | Descriptor: | Acetyl-coenzyme A synthetase 2-like, mitochondrial, NAD-dependent deacetylase sirtuin-3, ... | Authors: | Jin, L, Wei, W, Jiang, Y, Peng, H, Cai, J, Mao, C, Dai, H, Bemis, J.E, Jirousek, M.R, Milne, J.C, Westphal, C.H, Perni, R.B. | Deposit date: | 2009-03-12 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284, 2009
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2Q68
| Crystal Structure of Nak channel D66A, S70E double mutants | Descriptor: | CALCIUM ION, Potassium channel protein, SODIUM ION | Authors: | Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2007-06-04 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2Q69
| Crystal Structure of Nak channel D66N mutant | Descriptor: | CALCIUM ION, Potassium channel protein, SODIUM ION | Authors: | Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2007-06-04 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3GLS
| Crystal Structure of Human SIRT3 | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, SULFATE ION, ... | Authors: | Jin, L, Wei, W, Jiang, Y, Peng, H, Cai, J, Mao, C, Dai, H, Bemis, J.E, Jirousek, M.R, Milne, J.C, Westphal, C.H, Perni, R.B. | Deposit date: | 2009-03-12 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes. J.Biol.Chem., 284, 2009
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6NQ2
| Cryo-EM structure of human TPC2 channel in the ligand-bound closed state | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | Authors: | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-03-27 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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6NQ1
| Cryo-EM structure of human TPC2 channel in the apo state | Descriptor: | Two pore calcium channel protein 2 | Authors: | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2019-01-18 | Release date: | 2019-03-27 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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5WZI
| Structure of APUM23-GGAGUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*GP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5WZH
| Structure of APUM23-GGAAUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.509 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5WZG
| Structure of APUM23-GAAUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5WZJ
| Structure of APUM23-GGAUUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5YYZ
| Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | Descriptor: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-12-11 | Release date: | 2018-10-17 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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5Z4M
| Structure of TailorD343A with bound UTP and Mg | Descriptor: | MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | Deposit date: | 2018-01-11 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4D
| Structure of Tailor in complex with AGUU RNA | Descriptor: | RNA (5'-R(*AP*GP*UP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | Deposit date: | 2018-01-11 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4C
| Crystal structure of Tailor | Descriptor: | Terminal uridylyltransferase Tailor | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | Deposit date: | 2018-01-10 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5WZK
| Structure of APUM23-deletion-of-insert-region-GGAAUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5YYX
| Crystal Structure of the MEK1 FHA domain | Descriptor: | Meiosis-specific serine/threonine-protein kinase MEK1 | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-12-11 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.684 Å) | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
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5Z4J
| Structure of Tailor in complex with U4 RNA | Descriptor: | RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | Deposit date: | 2018-01-11 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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5Z4A
| Structure of Tailor in complex with AGU RNA | Descriptor: | RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | Deposit date: | 2018-01-10 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.637 Å) | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor. Nucleic Acids Res., 47, 2019
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8WZ2
| Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex | Descriptor: | G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y. | Deposit date: | 2023-11-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor. Cell Discov, 10, 2024
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