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PDB: 6 件
1L6S
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Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid
分子名称: 4,7-DIOXOSEBACIC ACID, MAGNESIUM ION, PORPHOBILINOGEN SYNTHASE, ...
著者Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A.
登録日2002-03-13
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
J.Biol.Chem., 277, 2002
1L6Y
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Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid
分子名称: 4-OXODECANEDIOIC ACID, GLYCEROL, MAGNESIUM ION, ...
著者Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A.
登録日2002-03-14
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
J.Biol.Chem., 277, 2002
5DEN
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The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
分子名称: FE (III) ION, Phenylalanine-4-hydroxylase
著者Arturo, E.C, Loll, P.J, Jaffe, E.K.
登録日2015-08-25
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Proc.Natl.Acad.Sci.USA, 113, 2016
1I8J
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CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4,7-DIOXOSEBACIC ACID
分子名称: 4,7-DIOXOSEBACIC ACID, MAGNESIUM ION, PORPHOBILINOGEN SYNTHASE, ...
著者Kervinen, J, Jaffe, E.K, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A.
登録日2001-03-14
公開日2001-06-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity.
Biochemistry, 40, 2001
6N1K
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Full-length human phenylalanine hydroxylase (PAH) in the resting state
分子名称: CHLORIDE ION, FE (III) ION, Phenylalanine-4-hydroxylase
著者Arturo, E.C, Jaffe, E.K.
登録日2018-11-08
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.057 Å)
主引用文献Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium.
J.Biol.Chem., 294, 2019
1PV8
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Crystal structure of a low activity F12L mutant of human porphobilinogen synthase
分子名称: 3-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID, Delta-aminolevulinic acid dehydratase, ZINC ION
著者Breinig, S, Kervinen, J, Stith, L, Wasson, A.S, Fairman, R, Wlodawer, A, Zdanov, A, Jaffe, E.K.
登録日2003-06-26
公開日2003-09-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Nat.Struct.Biol., 10, 2003

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