7NW3
 
 | | X-ray crystallographic study of PIYDIN, which contains the truncation determinants of binding PI and N, bound to RoAb13, a CCR5 antibody | | Descriptor: | Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain | | Authors: | Saridakis, E, Helliwell, J.R, Govada, L, Chayen, N.E. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.200011 Å) | | Cite: | X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5.
Iucrj, 8, 2021
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2K4Z
 | | Solution NMR Structure of Allochromatium vinosum DsrR: Northeast Structural Genomics Consortium Target OP5 | | Descriptor: | DsrR | | Authors: | Cort, J.R, Dahl, C, Grimm, F, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-22 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of the IscA-like Protein DsrR Involved in Sulfur Oxidation in Allochromatium vinosum
To be Published
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2KJR
 | | Solution NMR structure of the N-terminal Ubiquitin-like Domain from Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast Structural Genomics Consortium Target FR629A (residues 8-92) | | Descriptor: | CG11242 | | Authors: | Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-08 | | Release date: | 2009-06-23 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the N-terminal Ubiquitin-like Domain from
Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast
Structural Genomics Consortium Target FR629A (residues 8-92)
To be Published
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2KON
 | | NMR solution structure of CV_2116 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvT4(1-82) | | Descriptor: | Uncharacterized protein | | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Garcia, M, Yee, A, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-09-24 | | Release date: | 2009-10-13 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of CV_2116 from Chromobacterium violaceum.Northeast Structural Genomics Consortium Target CvT4(1-82)
To be Published
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2KNJ
 | | NMR structure of microplusin a antimicrobial peptide from Rhipicephalus (Boophilus) microplus | | Descriptor: | Microplusin preprotein | | Authors: | Pires, J.R, Rezende, C.A, Silva, F.D, Daffre, S. | | Deposit date: | 2009-08-26 | | Release date: | 2009-10-13 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Structure and mode of action of microplusin, a copper II-chelating antimicrobial peptide from the cattle tick Rhipicephalus (Boophilus) microplus.
J.Biol.Chem., 284, 2009
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7O7M
 | | (h-alpha2M)4 native II | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2KPU
 | | NMR Structure of YbbR family protein Dhaf_0833 (residues 32-118) from Desulfitobacterium hafniense DCB-2: Northeast Structural Genomics Consortium target DhR29B | | Descriptor: | YbbR family protein | | Authors: | Cort, J.R, Ramelot, T.A, Yang, Y, Belote, R.L, Ciccosanti, C, Haleema, J, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-10-20 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structures of domains I and IV from YbbR are representative of a widely distributed protein family.
Protein Sci., 20, 2011
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7O7N
 | | (h-alpha2M)4 semiactivated I state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7R
 | | (h-alpha2M)4 plasmin-activated I state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7O
 | | (h-alpha2M)4 semiactivated II state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7P
 | | (h-alpha2M)4 activated state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7S
 | | (h-alpha2M)4 plasmin-activated II state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7Q
 | | (h-alpha2M)4 trypsin-activated state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-13 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7O7L
 | | (h-alpha2M)4 native I | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | | Authors: | Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. | | Deposit date: | 2021-04-13 | | Release date: | 2022-04-20 | | Last modified: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2HAC
 | | Structure of Zeta-Zeta Transmembrane Dimer | | Descriptor: | T-cell surface glycoprotein CD3 zeta chain | | Authors: | Chou, J.J, Wucherpfennig, K.W, Schnell, J.R, Call, M.E. | | Deposit date: | 2006-06-12 | | Release date: | 2006-10-31 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor.
Cell(Cambridge,Mass.), 127, 2006
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2GM2
 | | NMR structure of Xanthomonas campestris XCC1710: Northeast Structural Genomics Consortium target XcR35 | | Descriptor: | conserved hypothetical protein | | Authors: | Cort, J.R, Xiao, R, Wang, D.Y, Ma, L.C, Ciano, M, Montelione, G.T, Ramelot, T.A, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-04-05 | | Release date: | 2006-04-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structure of Xanthomonas campestris XCC1710 protein
To be Published
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2H6D
 | | Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain) | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | | Authors: | Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-05-31 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
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2IBI
 | | Covalent Ubiquitin-USP2 Complex | | Descriptor: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ... | | Authors: | Walker, J.R, Avvakumov, G.V, Bernstein, G, Xue, S, Finerty Jr, P.J, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-09-11 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Covalent Ubiquitin-USP2 Complex
To be Published
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2K4N
 | | NMR structure of protein PF0246 from Pyrococcus furiosus: target PfR75 from the Northeast Structural Genomics Consortium | | Descriptor: | Protein PF0246 | | Authors: | Cort, J.R, Ho, C.K, Shetty, K, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-13 | | Release date: | 2008-08-12 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution-State NMR Structure of protein PF0246 from Pyrococcus Furiosis
To be Published
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2KPI
 | | Solution NMR structure of Streptomyces coelicolor SCO3027 modeled with Zn+2 bound, Northeast Structural Genomics Consortium Target RR58 | | Descriptor: | Uncharacterized protein SCO3027, ZINC ION | | Authors: | Ramelot, T.A, Cort, J.R, Garcia, M, Yee, A, Arrowmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-10-15 | | Release date: | 2010-02-02 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Streptomyces coelicolor SCO3027 modeled with Zn+2 bound, Northeast Structural Genomics Consortium Target RR58
To be Published
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2KS0
 | | Solution NMR structure of the Q251Q8_DESHY(21-82) protein from Desulfitobacterium Hafniense, Northeast Structural Genomics Consortium Target DhR8C | | Descriptor: | Uncharacterized protein | | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-12-23 | | Release date: | 2010-01-12 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
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2K5T
 | | Solution NMR Structure of Putative N-Acetyl Transferase YhhK from E. coli Bound to Coenzyme A: Northeast Structural Genomics Consortium Target ET106 | | Descriptor: | COENZYME A, Uncharacterized protein yhhK | | Authors: | Cort, J.R, Yee, A, Montelione, G.T, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-30 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Putative N-Acetyl Transferase YhhK from E. coli Bound to Coenzyme A
To be Published
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2KJ8
 | | NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli: Northeast Structural Genomics Consortium target ER652A, PSI-2 | | Descriptor: | Putative prophage CPS-53 integrase | | Authors: | Cort, J.R, Ramelot, T.A, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Swapna, G, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-05-25 | | Release date: | 2009-07-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli
To be Published
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2KBI
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2FO8
 | | Solution structure of the Trypanosoma cruzi cysteine protease inhibitor chagasin | | Descriptor: | Chagasin | | Authors: | Salmon, D, do Aido-Machado, R, de Lima, A.A.P, Scharfstein, J, Oschkinat, H, Pires, J.R. | | Deposit date: | 2006-01-13 | | Release date: | 2006-04-04 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin
J.Mol.Biol., 357, 2006
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