1LSH
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2FK9
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![BU of 2fk9 by Molmil](/molmil-images/mine/2fk9) | Human protein kinase C, eta | 分子名称: | protein kinase C, eta type | 著者 | Walker, J.R, Littler, D.R, Finerty Jr, P.J, MacKenzie, F, Newman, E.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-04 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites. Biochem.Biophys.Res.Commun., 349, 2006
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2ETX
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![BU of 2etx by Molmil](/molmil-images/mine/2etx) | Crystal Structure of MDC1 Tandem BRCT Domains | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Wasielewski, E, Kim, Y, Joachimiak, A, Thompson, J.R, Mer, G. | 登録日 | 2005-10-27 | 公開日 | 2005-11-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. J.Biol.Chem., 287, 2012
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1M6T
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![BU of 1m6t by Molmil](/molmil-images/mine/1m6t) | CRYSTAL STRUCTURE OF B562RIL, A REDESIGNED FOUR HELIX BUNDLE | 分子名称: | SULFATE ION, Soluble cytochrome b562 | 著者 | Chu, R, Takei, J, Knowlton, J.R, Andrykovitch, M, Pei, W, Kajava, A.V, Steinbach, P.J, Ji, X, Bai, Y. | 登録日 | 2002-07-17 | 公開日 | 2002-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Redesign of a Four-Helix Bundle Protein by Phage Display Coupled with Proteolysis
and Structural Characterization by NMR and X-ray Crystallography J.Mol.Biol., 323, 2002
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4N23
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![BU of 4n23 by Molmil](/molmil-images/mine/4n23) | Crystal structure of the GP2 Core Domain from the California Academy of Science Virus, monoclinic symmetry | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain | 著者 | Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-10-04 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J.Mol.Biol., 426, 2014
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2D5Z
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![BU of 2d5z by Molmil](/molmil-images/mine/2d5z) | Crystal structure of T-state human hemoglobin complexed with three L35 molecules | 分子名称: | 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID, Hemoglobin alpha subunit, Hemoglobin beta subunit, ... | 著者 | Yokoyama, T, Neya, S, Tsuneshige, A, Yonetani, T, Park, S.Y, Tame, J.R. | 登録日 | 2005-11-08 | 公開日 | 2006-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35 J.Mol.Biol., 356, 2006
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2D60
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![BU of 2d60 by Molmil](/molmil-images/mine/2d60) | Crystal structure of deoxy human hemoglobin complexed with two L35 molecules | 分子名称: | 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID, Hemoglobin alpha subunit, Hemoglobin beta subunit, ... | 著者 | Yokoyama, T, Neya, S, Tsuneshige, A, Yonetani, T, Park, S.Y, Tame, J.R. | 登録日 | 2005-11-08 | 公開日 | 2006-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35 J.Mol.Biol., 356, 2006
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4NU5
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![BU of 4nu5 by Molmil](/molmil-images/mine/4nu5) | Crystal Structure of PTDH R301A | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase | 著者 | Nair, S.K, Chekan, J.R. | 登録日 | 2013-12-03 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
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4NXJ
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![BU of 4nxj by Molmil](/molmil-images/mine/4nxj) | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum | 分子名称: | Bromodomain protein | 著者 | Wernimont, A.K, Loppnau, P, Knapp, S, Fonseca, M, Brennan, P.E, Dong, A, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-09 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum TO BE PUBLISHED
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2D5X
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![BU of 2d5x by Molmil](/molmil-images/mine/2d5x) | Crystal structure of carbonmonoxy horse hemoglobin complexed with L35 | 分子名称: | 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID, CARBON MONOXIDE, Hemoglobin alpha subunit, ... | 著者 | Yokoyama, T, Neya, S, Tsuneshige, A, Yonetani, T, Park, S.Y, Tame, J.R. | 登録日 | 2005-11-08 | 公開日 | 2006-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35 J.Mol.Biol., 356, 2006
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4NKH
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![BU of 4nkh by Molmil](/molmil-images/mine/4nkh) | Crystal structure of SspH1 LRR domain | 分子名称: | E3 ubiquitin-protein ligase sspH1 | 著者 | Keszei, A.F.A, Xiaojing, T, Mccormick, C, Zeqiraj, E, Rohde, J.R, Tyers, M, Sicheri, F. | 登録日 | 2013-11-12 | 公開日 | 2013-12-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Mol.Cell.Biol., 34, 2014
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2F4W
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![BU of 2f4w by Molmil](/molmil-images/mine/2f4w) | Human ubiquitin-conjugating enzyme E2 J2 | 分子名称: | ubiquitin-conjugating enzyme E2, J2 | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-11-24 | 公開日 | 2005-12-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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4NSJ
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![BU of 4nsj by Molmil](/molmil-images/mine/4nsj) | Carboplatin binding to HEWL in 2M NH4formate, 0.1M HEPES at pH 7.5 | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, Lysozyme C, ... | 著者 | Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. | 登録日 | 2013-11-28 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Carboplatin binding to histidine. Acta Crystallogr F Struct Biol Commun, 70, 2014
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1LVO
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![BU of 1lvo by Molmil](/molmil-images/mine/1lvo) | Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIETHYLENE DIOXIDE, Replicase, ... | 著者 | Anand, K, Palm, G.J, Mesters, J.R, Siddell, S.G, Ziebuhr, J, Hilgenfeld, R. | 登録日 | 2002-05-29 | 公開日 | 2002-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain. EMBO J., 21, 2002
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1LWL
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![BU of 1lwl by Molmil](/molmil-images/mine/1lwl) | Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide) | 分子名称: | ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Cytochrome P450-cam, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Dunn, A.R, Hays, A.M, Goodin, D.B, Stout, C.D, Chiu, R, Winkler, J.R, Gray, H.B. | 登録日 | 2002-05-31 | 公開日 | 2002-12-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Fluorescent probes for cytochrome P450 structural characterization and inhibitor screening J.AM.CHEM.SOC., 124, 2002
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4O2Z
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![BU of 4o2z by Molmil](/molmil-images/mine/4o2z) | Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594 | 分子名称: | 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide, Mitogen-activated protein kinase 3, putative | 著者 | Wernimont, A.K, Walker, J.R, Hutchinson, A, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Hui, R, Mangos, M, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-17 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594 To be Published
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2F7D
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![BU of 2f7d by Molmil](/molmil-images/mine/2f7d) | A mutant rabbit cathepsin K with a nitrile inhibitor | 分子名称: | (1R,2R)-N-(2-AMINOETHYL)-2-{[(4-METHOXYPHENYL)SULFONYL]METHYL}CYCLOHEXANECARBOXAMIDE, Cathepsin K | 著者 | Somoza, J.R. | 登録日 | 2005-11-30 | 公開日 | 2006-03-07 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K. J.Med.Chem., 49, 2006
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2F8C
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![BU of 2f8c by Molmil](/molmil-images/mine/2f8c) | Crystal structure of FPPS in complex with Zoledronate | 分子名称: | Farnesyl Diphosphate Synthase, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-02 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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2F92
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![BU of 2f92 by Molmil](/molmil-images/mine/2f92) | Crystal structure of human FPPS in complex with alendronate | 分子名称: | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, Farnesyl Diphosphate Synthase, PHOSPHATE ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-05 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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1IUL
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![BU of 1iul by Molmil](/molmil-images/mine/1iul) | The structure of cell-free ID.343 from Thermus thermophilus | 分子名称: | hypothetical protein TT1466 | 著者 | Wada, T, Shirouzu, M, Park, S.-Y, Tame, J.R, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-03-05 | 公開日 | 2003-07-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a conserved CoA-binding protein synthesized by a cell-free system. Acta Crystallogr.,Sect.D, 59, 2003
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2DN2
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![BU of 2dn2 by Molmil](/molmil-images/mine/2dn2) | 1.25A resolution crystal structure of human hemoglobin in the deoxy form | 分子名称: | Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Park, S.-Y, Yokoyama, T, Shibayama, N, Shiro, Y, Tame, J.R. | 登録日 | 2006-04-25 | 公開日 | 2006-05-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | 1.25 a resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms. J.Mol.Biol., 360, 2006
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1IZH
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![BU of 1izh by Molmil](/molmil-images/mine/1izh) | Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants | 分子名称: | proteinase, {(1S)-1-BENZYL-4-[3-CARBAMOYL-1-(1-CARBAMOYL-2-PHENYL-ETHYLCARBAMOYL)-(S)-PROPYLCARBAMOYL]-2-OXO-5-PHENYL-PENTYL}-CARBAMIC ACID TERT-BUTYL ESTER | 著者 | Weber, J, Mesters, J.R, Lepsik, M, Prejdova, J, Svec, M, Sponarova, J, Mlcochova, P, Skalicka, K, Strisovsky, K, Uhlikova, T, Soucek, M, Machala, L, Stankova, M, Vondrasek, J, Klimkait, T, Kraeusslich, H.-G, Hilgenfeld, R, Konvalinka, J. | 登録日 | 2002-10-02 | 公開日 | 2002-12-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unusual Binding Mode of an HIV-1 Protease Inhibitor Explains its Potency against Multi-drug-resistant Virus Strains J.MOL.BIOL., 324, 2002
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2DSM
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![BU of 2dsm by Molmil](/molmil-images/mine/2dsm) | NMR Structure of Bacillus Subtilis Protein YqaI, Northeast Structural Genomics Target SR450 | 分子名称: | Hypothetical protein yqaI | 著者 | Ramelot, T.A, Cort, J.R, Wang, D, Janua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-07-01 | 公開日 | 2006-08-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Bacillus Subtilis Protein YqaI, Northeast Structural Genomics Target SR450 to be published
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1IT2
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![BU of 1it2 by Molmil](/molmil-images/mine/1it2) | Hagfish deoxy hemoglobin | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, hemoglobin | 著者 | Mito, M, Chong, K.T, Park, S.-Y, Tame, J.R. | 登録日 | 2002-01-05 | 公開日 | 2002-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri J.Biol.Chem., 277, 2002
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4NU6
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![BU of 4nu6 by Molmil](/molmil-images/mine/4nu6) | Crystal Structure of PTDH R301K | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase, SULFATE ION | 著者 | Nair, S.K, Chekan, J.R. | 登録日 | 2013-12-03 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
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