4O2Z
Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594
Summary for 4O2Z
Entry DOI | 10.2210/pdb4o2z/pdb |
Descriptor | Mitogen-activated protein kinase 3, putative, 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide (3 entities in total) |
Functional Keywords | neglected disease, structural genomics, structural genomics consortium, sgc, kinase, transferase |
Biological source | Leishmania donovani |
Total number of polymer chains | 1 |
Total formula weight | 43789.98 |
Authors | Wernimont, A.K.,Walker, J.R.,Hutchinson, A.,Loppnau, P.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Mangos, M.,Structural Genomics Consortium (SGC) (deposition date: 2013-12-17, release date: 2014-01-22, Last modification date: 2023-09-20) |
Primary citation | Wernimont, A.K.,Walker, J.R.,Hutchinson, A.,Loppnau, P.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Mangos, M.,Structural Genomics Consortium (SGC) Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594 To be Published, |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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