Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000165 | biological_process | MAPK cascade |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0004707 | molecular_function | MAP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 046 A 401 |
| Chain | Residue |
| A | SER74 |
| A | ALA172 |
| A | HIS173 |
| A | ASP175 |
| A | ILE191 |
| A | ASP193 |
| A | PHE194 |
| A | SER356 |
| A | GLU94 |
| A | MET97 |
| A | MET98 |
| A | LEU107 |
| A | THR130 |
| A | PRO131 |
| A | MET133 |
| A | ASP134 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGMGAYGIACsCldgdtgekv.........SIKK |
| Chain | Residue | Details |
| A | LEU53-LYS77 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VaHrDLKpaNLVT |
| Chain | Residue | Details |
| A | VAL171-THR183 | |
| site_id | PS01351 |
| Number of Residues | 106 |
| Details | MAPK MAP kinase signature. FrdvedgkrvlREidmmrffhhenllnvvnilpplkreyhsfedvyvvtplmdvdmnvvlrsrqvleeshmqyfvyqilrglkylhsanvah.......RDlKpanlvtnisC |
| Chain | Residue | Details |
| A | PHE82-CYS187 | |
