3R56
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![BU of 3r56 by Molmil](/molmil-images/mine/3r56) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 1H-indazol-6-amine, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-18 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R92
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![BU of 3r92 by Molmil](/molmil-images/mine/3r92) | Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. | Descriptor: | (3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14,15,17,18,19-dodecahydro-13H-10,6-(metheno)pyrrolo[2',1':3,4][1,4,9]triazacyclotetradecino[9,8-a]indole-7-carboxamide, Heat shock protein HSP 90-alpha | Authors: | Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Golas, J.M, Liu, H, Lucas, J, Boschelli, F, Vogan, E.M, Levin, J.I. | Deposit date: | 2011-03-24 | Release date: | 2011-06-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5801 Å) | Cite: | Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Bioorg.Med.Chem.Lett., 21, 2011
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3J27
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![BU of 3j27 by Molmil](/molmil-images/mine/3j27) | CryoEM structure of Dengue virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Zhang, X, Ge, P, Yu, X, Brannan, J.M, Bi, G, Zhang, Q, Schein, S, Zhou, Z.H. | Deposit date: | 2012-09-26 | Release date: | 2012-12-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution. Nat.Struct.Mol.Biol., 20, 2012
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3J3P
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![BU of 3j3p by Molmil](/molmil-images/mine/3j3p) | Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 135S Poliovirus and C3-Fab Complex | Descriptor: | C3 antibody, heavy chain, light chain, ... | Authors: | Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M. | Deposit date: | 2013-04-10 | Release date: | 2013-07-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy. J.Immunol., 191, 2013
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3K60
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![BU of 3k60 by Molmil](/molmil-images/mine/3k60) | |
3S9G
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![BU of 3s9g by Molmil](/molmil-images/mine/3s9g) | |
3JBF
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![BU of 3jbf by Molmil](/molmil-images/mine/3jbf) | Complex of poliovirus with VHH PVSP19B | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M. | Deposit date: | 2015-08-26 | Release date: | 2016-01-27 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site. J.Virol., 90, 2016
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3JAO
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![BU of 3jao by Molmil](/molmil-images/mine/3jao) | Ciliary microtubule doublet | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Maheshwari, A, Obbineni, J.M, Bui, K.H, Shibata, K, Toyoshima, Y.Y, Ishikawa, T. | Deposit date: | 2015-06-18 | Release date: | 2015-08-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | alpha- and beta-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography. Structure, 23, 2015
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3JBC
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![BU of 3jbc by Molmil](/molmil-images/mine/3jbc) | Complex of Poliovirus with VHH PVSP29F | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M. | Deposit date: | 2015-08-26 | Release date: | 2016-01-27 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site. J.Virol., 90, 2016
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3JBG
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![BU of 3jbg by Molmil](/molmil-images/mine/3jbg) | Complex of poliovirus with VHH PVSS21E | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M. | Deposit date: | 2015-08-26 | Release date: | 2016-01-27 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site. J.Virol., 90, 2016
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3JVX
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![BU of 3jvx by Molmil](/molmil-images/mine/3jvx) | Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120A) | Descriptor: | 6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Anderson, A.C, Beierlein, J.M, Karri, N.G. | Deposit date: | 2009-09-17 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mutational Studies into Trimethoprim Resistance in Bacillus anthracis Dihydrofolate Reductase To be Published
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3JW5
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![BU of 3jw5 by Molmil](/molmil-images/mine/3jw5) | |
3S9U
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![BU of 3s9u by Molmil](/molmil-images/mine/3s9u) | |
3SJQ
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![BU of 3sjq by Molmil](/molmil-images/mine/3sjq) | Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin | Descriptor: | 1-phenylurea, CALCIUM ION, Calmodulin, ... | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | Deposit date: | 2011-06-21 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for calmodulin as a dynamic calcium sensor. Structure, 20, 2012
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3K4E
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![BU of 3k4e by Molmil](/molmil-images/mine/3k4e) | Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A | Descriptor: | RNA (5'-R(P*CP*UP*UP*GP*UP*AP*UP*AP*UP*A)-3'), mRNA-binding protein PUF3 | Authors: | Zhu, D, Stumpf, C.R, Krahn, J.M, Wickens, M, Hall, T.M.T. | Deposit date: | 2009-10-05 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 106, 2009
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3J48
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![BU of 3j48 by Molmil](/molmil-images/mine/3j48) | Cryo-EM structure of Poliovirus 135S particles | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | Authors: | Butan, C, Fiman, D.J, Hogle, J.M. | Deposit date: | 2013-06-28 | Release date: | 2013-12-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Cryo-Electron Microscopy Reconstruction Shows Poliovirus 135S Particles Poised for Membrane Interaction and RNA Release. J.Virol., 88, 2014
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3J4B
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![BU of 3j4b by Molmil](/molmil-images/mine/3j4b) | Structure of T7 gatekeeper protein (gp11) | Descriptor: | Tail tubular protein A | Authors: | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | Deposit date: | 2013-07-09 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structural characterization of the bacteriophage t7 tail machinery. J.Biol.Chem., 288, 2013
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3QVD
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![BU of 3qvd by Molmil](/molmil-images/mine/3qvd) | Exposure of rubrerythrin from Pyrococcus furiosus to peroxide, fifteen second time point. | Descriptor: | FE (II) ION, FE (III) ION, HYDROGEN PEROXIDE, ... | Authors: | Dillard, B.D, Demick, J.M, Adams, M.W.W, Lanzilotta, W.N. | Deposit date: | 2011-02-25 | Release date: | 2011-06-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A cryo-crystallographic time course for peroxide reduction by rubrerythrin from Pyrococcus furiosus. J.Biol.Inorg.Chem., 16, 2011
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3KML
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![BU of 3kml by Molmil](/molmil-images/mine/3kml) | |
3L49
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![BU of 3l49 by Molmil](/molmil-images/mine/3l49) | CRYSTAL STRUCTURE OF ABC SUGAR TRANSPORTER SUBUNIT FROM Rhodobacter sphaeroides 2.4.1 | Descriptor: | ABC sugar (Ribose) transporter, periplasmic substrate-binding subunit, UNKNOWN LIGAND | Authors: | Patskovsky, Y, Ozyurt, S, Dickey, M, Do, J, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-12-18 | Release date: | 2010-01-05 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CRYSTAL STRUCTURE OF ABC SUGAR TRANSPORTER FROM Rhodobacter sphaeroides To be Published
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3KTS
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![BU of 3kts by Molmil](/molmil-images/mine/3kts) | CRYSTAL STRUCTURE OF GLYCEROL UPTAKE OPERON ANTITERMINATOR REGULATORY PROTEIN FROM LISTERIA MONOCYTOGENES STR. 4b F2365 | Descriptor: | Glycerol uptake operon antiterminator regulatory protein, UNKNOWN LIGAND | Authors: | Patskovsky, Y, Toro, R, Freeman, J, Do, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-11-25 | Release date: | 2009-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | CRYSTAL STRUCTURE OF GLYCEROL UPTAKE OPERON ANTITERMINATOR REGULATORY PROTEIN FROM LISTERIA MONOCYTOGENES STR. 4b F2365 To be Published
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3KPT
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![BU of 3kpt by Molmil](/molmil-images/mine/3kpt) | Crystal structure of BcpA, the major pilin subunit of Bacillus cereus | Descriptor: | CALCIUM ION, Collagen adhesion protein | Authors: | Poor, C.B, Budzik, J.M, Schneewind, O, He, C. | Deposit date: | 2009-11-16 | Release date: | 2009-11-24 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc.Natl.Acad.Sci.USA, 106, 2009
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3RKP
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![BU of 3rkp by Molmil](/molmil-images/mine/3rkp) | Crystal structure of BcpA*(D312A), the major pilin subunit of Bacillus cereus | Descriptor: | Collagen adhesion protein | Authors: | Hendrickx, A.P, Poor, C.B, Jureller, J.E, Budzik, J.M, He, C, Schneewind, O. | Deposit date: | 2011-04-18 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.243 Å) | Cite: | Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Mol.Microbiol., 85, 2012
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3RTO
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![BU of 3rto by Molmil](/molmil-images/mine/3rto) | Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure | Descriptor: | Insulin, ZINC ION | Authors: | Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. | Deposit date: | 2011-05-03 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
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3IYC
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![BU of 3iyc by Molmil](/molmil-images/mine/3iyc) | Poliovirus late RNA-release intermediate | Descriptor: | Capsid protein VP1, Capsid protein VP2, Genome polyprotein, ... | Authors: | Levy, H.C, Bostina, M, Filman, D.J, Hogle, J.M. | Deposit date: | 2009-07-21 | Release date: | 2010-03-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy. J.Virol., 84, 2010
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