3S9U

Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J

Summary for 3S9U

• Entry DOI: 10.2210/pdb3s9u/pdb
• Related: 3E0B 3JVX 3JWC 3JWF 3JWK 3JWM 3SA1 3SA2 3SAI
• Descriptor: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, ... (4 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Bacillus anthracis (anthrax,anthrax bacterium)
• Total number of polymer chains: 2
• Total formula weight: 41418.34

Authors

Anderson, A.C.,Beierlein, J.M. (deposition date: 2011-06-02, release date: 2012-06-13, Last modification date: 2023-09-13)

• Primary citation: Anderson, A.C.,Beierlein, J.M.,Viswanathan, K.,Wright, D.L.; Structure-Activity Studies of Heterocyclic Propargyl-linked TMP Analogs Targeting Bacillus anthracis Dihydrofolate Reductase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)