3JW5

Crystal structure of Bacillus anthracis (Y102F) dihydrofolate reductase complexed with NADPH and Trimethoprim

Summary for 3JW5

• Entry DOI: 10.2210/pdb3jw5/pdb
• Related: 3EOB 3JV3 3JVX
• Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM, ... (4 entities in total)
• Functional Keywords: oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Bacillus anthracis
• Total number of polymer chains: 2
• Total formula weight: 42083.02

Authors

Anderson, A.C.,Beierlein, J.M.,Karri, N.G. (deposition date: 2009-09-17, release date: 2010-09-15, Last modification date: 2023-09-06)

• Primary citation: Beierlein, J.M.,Karri, N.G.,Anderson, A.C.; Mutational Studies into Trimethoprim Resistance in Bacillus anthracis Dihydrofolate Reductase; To be Published,

Experimental method

X-RAY DIFFRACTION (2.89 Å)