6BLE
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![BU of 6ble by Molmil](/molmil-images/mine/6ble) | Crystal Structure of the Human CAMKK2B in complex with CP673451 | 分子名称: | 1-{2-[5-(2-methoxyethoxy)-1H-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine, Calcium/calmodulin-dependent protein kinase kinase 2, GLYCEROL | 著者 | Counago, R.M, dos Reis, C.V, de Souza, G.P, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2017-11-10 | 公開日 | 2017-11-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Human CAMKK2B in complex with CP673451 To Be Published
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1LK0
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![BU of 1lk0 by Molmil](/molmil-images/mine/1lk0) | Disulfide intermediate of C89L Arsenate reductase from pI258 | 分子名称: | CHLORIDE ION, POTASSIUM ION, arsenate reductase | 著者 | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | 登録日 | 2002-04-23 | 公開日 | 2002-08-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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6CI2
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![BU of 6ci2 by Molmil](/molmil-images/mine/6ci2) | Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, formyltransferase PseJ | 著者 | Reimer, J.M, Jiang, J, Harb, I, Schmeing, T.M. | 登録日 | 2018-02-23 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem. Biol., 13, 2018
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1LCS
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![BU of 1lcs by Molmil](/molmil-images/mine/1lcs) | RECEPTOR-BINDING DOMAIN FROM SUBGROUP B FELINE LEUKEMIA VIRUS | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Barnett, A.L, Wensel, D.L, Li, W, Fass, D, Cunningham, J.M. | 登録日 | 2002-04-06 | 公開日 | 2003-04-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Mechanism of a Coreceptor for Infection by a pathogenic feline retrovirus J.Virol., 77, 2003
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6CPY
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![BU of 6cpy by Molmil](/molmil-images/mine/6cpy) | Structure of apo GRMZM2G135359 pseudokinase | 分子名称: | GRMZM2G135359 pseudokinase | 著者 | Aquino, B, Counago, R.M, Godoi, P.H.C, Massirer, K.B, Elkins, J.M, Arruda, P, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-14 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of apo GRMZM2G135359 pseudokinase To be Published
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6CSW
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![BU of 6csw by Molmil](/molmil-images/mine/6csw) | Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor | 分子名称: | (7R)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5H)-one, ACETATE ION, CHLORIDE ION, ... | 著者 | dos Reis, C.V, de Souza, G.P, Counago, R.M, Chiodi, C.G, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-21 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor To Be Published
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6CMM
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![BU of 6cmm by Molmil](/molmil-images/mine/6cmm) | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine inhibitor | 分子名称: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | dos Reis, C.V, de Souza, G.P, Counago, R.M, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-05 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine inhibitor To Be Published
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6CWU
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![BU of 6cwu by Molmil](/molmil-images/mine/6cwu) | Protein Tyrosine Phosphatase 1B F135Y mutant | 分子名称: | MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Hjortness, M, Zwart, P, Sankaran, B, Fox, J.M. | 登録日 | 2018-03-31 | 公開日 | 2018-10-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry, 57, 2018
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1IC1
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![BU of 1ic1 by Molmil](/molmil-images/mine/1ic1) | THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, INTERCELLULAR ADHESION MOLECULE-1 | 著者 | Casasnovas, J.M, Stehle, T, Liu, J.-H, Wang, J.-H, Springer, T.A. | 登録日 | 1998-03-09 | 公開日 | 1998-06-17 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proc.Natl.Acad.Sci.USA, 95, 1998
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1IBK
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![BU of 1ibk by Molmil](/molmil-images/mine/1ibk) | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | 登録日 | 2001-03-28 | 公開日 | 2001-05-04 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 2001
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6BQP
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![BU of 6bqp by Molmil](/molmil-images/mine/6bqp) | Crystal Structure of the Human CAMKK2B in complex with Crenolanib | 分子名称: | 1,2-ETHANEDIOL, 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, Calcium/calmodulin-dependent protein kinase kinase 2 | 著者 | Counago, R.M, de Souza, G.P, dos Reis, C.V, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2017-11-28 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of the Human CAMKK2B in complex with Crenolanib To Be Published
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6BHT
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![BU of 6bht by Molmil](/molmil-images/mine/6bht) | HIV-1 CA hexamer in complex with IP6, orthorhombic crystal form | 分子名称: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | 著者 | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | 登録日 | 2017-10-31 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.689 Å) | 主引用文献 | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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6BHS
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![BU of 6bhs by Molmil](/molmil-images/mine/6bhs) | HIV-1 CA hexamer in complex with IP6, hexagonal crystal form | 分子名称: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | 著者 | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | 登録日 | 2017-10-31 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.984 Å) | 主引用文献 | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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6BNX
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![BU of 6bnx by Molmil](/molmil-images/mine/6bnx) | Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P6(3) | 分子名称: | COBALT (II) ION, Lactoylglutathione lyase | 著者 | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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1L5B
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![BU of 1l5b by Molmil](/molmil-images/mine/1l5b) | DOMAIN-SWAPPED CYANOVIRIN-N DIMER | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, cyanovirin-N | 著者 | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | 登録日 | 2002-03-06 | 公開日 | 2002-05-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
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6CY0
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![BU of 6cy0 by Molmil](/molmil-images/mine/6cy0) | RNA octamer containing 2'-F, 4'-Cbeta-OMe U. | 分子名称: | RNA (5'-R(*(CBV)P*GP*AP*AP*(UFB)P*UP*CP*G)-3') | 著者 | Harp, J.M, Egli, M. | 登録日 | 2018-04-04 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | 主引用文献 | Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Nucleic Acids Res., 46, 2018
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1L5I
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![BU of 1l5i by Molmil](/molmil-images/mine/1l5i) | 30-CONFORMER NMR ENSEMBLE OF THE N-TERMINAL, DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN FROM A GEMINIVIRUS (TOMATO YELLOW LEAF CURL VIRUS-SARDINIA) | 分子名称: | Rep protein | 著者 | Campos-Olivas, R, Louis, J.M, Clerot, D, Gronenborn, B, Gronenborn, A.M. | 登録日 | 2002-03-07 | 公開日 | 2002-09-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of a replication initiator unites diverse aspects of nucleic acid metabolism Proc.Natl.Acad.Sci.USA, 99, 2002
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6BTW
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![BU of 6btw by Molmil](/molmil-images/mine/6btw) | Crystal Structure of the Human vaccinia-related kinase bound to a phenyl-pteridinone inhibitor | 分子名称: | 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5H)-one, CHLORIDE ION, GLYCEROL, ... | 著者 | Counago, R.M, dos Reis, C.V, de Souza, G.P, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2017-12-07 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Human vaccinia-related kinase bound to a phenyl-pteridinone inhibitor To Be Published
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6BNN
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![BU of 6bnn by Molmil](/molmil-images/mine/6bnn) | Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | 分子名称: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | 著者 | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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1JE5
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![BU of 1je5 by Molmil](/molmil-images/mine/1je5) | Crystal Structure of gp2.5, a Single-Stranded DNA Binding Protein Encoded by Bacteriophage T7 | 分子名称: | CALCIUM ION, HELIX-DESTABILIZING PROTEIN | 著者 | Hollis, T, Stattel, J.M, Walther, D.S, Richardson, C.C, Ellenberger, T.E. | 登録日 | 2001-06-15 | 公開日 | 2001-08-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7. Proc.Natl.Acad.Sci.USA, 98, 2001
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1JUG
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![BU of 1jug by Molmil](/molmil-images/mine/1jug) | |
1K1T
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![BU of 1k1t by Molmil](/molmil-images/mine/1k1t) | Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN, SULFATE ION | 著者 | Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2001-09-25 | 公開日 | 2002-07-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Combining mutations in HIV-1 protease to understand mechanisms of resistance. Proteins, 48, 2002
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6CY4
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![BU of 6cy4 by Molmil](/molmil-images/mine/6cy4) | RNA octamer containing 2'-OMe, 4'- Cbeta-OMe U. | 分子名称: | RNA (5'-R(*(CBV)P*GP*AP*AP*(UOB)P*UP*CP*G)-3') | 著者 | Harp, J.M, Egli, M. | 登録日 | 2018-04-04 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Nucleic Acids Res., 46, 2018
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1LJL
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![BU of 1ljl by Molmil](/molmil-images/mine/1ljl) | Wild Type pI258 S. aureus arsenate reductase | 分子名称: | POTASSIUM ION, arsenate reductase | 著者 | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | 登録日 | 2002-04-21 | 公開日 | 2002-08-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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6CCX
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![BU of 6ccx by Molmil](/molmil-images/mine/6ccx) | NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | 分子名称: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | 著者 | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | 登録日 | 2018-02-07 | 公開日 | 2018-09-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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