6CWU
Protein Tyrosine Phosphatase 1B F135Y mutant
Summary for 6CWU
Entry DOI | 10.2210/pdb6cwu/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1, MAGNESIUM ION (3 entities in total) |
Functional Keywords | insulin signaling, diabetes, cancer, signaling, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38477.08 |
Authors | Hjortness, M.,Zwart, P.,Sankaran, B.,Fox, J.M. (deposition date: 2018-03-31, release date: 2018-10-31, Last modification date: 2023-10-04) |
Primary citation | Hjortness, M.K.,Riccardi, L.,Hongdusit, A.,Zwart, P.H.,Sankaran, B.,De Vivo, M.,Fox, J.M. Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry, 57:6443-6451, 2018 Cited by PubMed: 30289703DOI: 10.1021/acs.biochem.8b00656 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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