6BQP

Crystal Structure of the Human CAMKK2B in complex with Crenolanib

Summary for 6BQP

• Entry DOI: 10.2210/pdb6bqp/pdb
• Descriptor: Calcium/calmodulin-dependent protein kinase kinase 2, 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase inhibitor complex
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 33632.86

Authors

Counago, R.M.,de Souza, G.P.,dos Reis, C.V.,Ramos, P.Z.,Drewry, D.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (deposition date: 2017-11-28, release date: 2017-12-13, Last modification date: 2023-10-04)

• Primary citation: Counago, R.M.,de Souza, G.P.,dos Reis, C.V.,Drewry, D.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC); Crystal Structure of the Human CAMKK2B in complex with Crenolanib; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)