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PDB: 5623 件

4BD7
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Bax domain swapped dimer induced by octylmaltoside
分子名称: APOPTOSIS REGULATOR BAX, CHLORIDE ION, PRASEODYMIUM ION
著者Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M.
登録日2012-10-05
公開日2013-02-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
4BIU
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Crystal structure of CpxAHDC (orthorhombic form 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION
著者Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M.
登録日2013-04-13
公開日2014-02-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
Plos Biol., 12, 2014
4BTP
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Structure of the capsid protein P1 of the bacteriophage phi8
分子名称: p1
著者El Omari, K, Sutton, G, Ravantti, J.J, Zhang, H, Walter, T.S, Grimes, J.M, Bamford, D.H, Stuart, D.I, Mancini, E.J.
登録日2013-06-18
公開日2013-08-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses
Structure, 21, 2013
4CD8
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The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManMIm
分子名称: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ENDO-BETA-1,4-MANNANASE, beta-D-mannopyranose
著者Williams, R.J, Iglesias-Fernandez, J, Stepper, J, Jackson, A, Thompson, A.J, Lowe, E.C, White, J.M, Gilbert, H.J, Rovira, C, Davies, G.J, Williams, S.J.
登録日2013-10-30
公開日2014-04-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate.
Angew.Chem.Int.Ed.Engl., 53, 2014
1JL2
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Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H
分子名称: Chimera of Ribonuclease HI, Ribonuclease H
著者Robic, S, Berger, J.M, Marqusee, S.
登録日2001-07-13
公開日2002-01-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Contributions of folding cores to the thermostabilities of two ribonucleases H.
Protein Sci., 11, 2002
4F09
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Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
分子名称: 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
著者Murray, J.M.
登録日2012-05-03
公開日2012-07-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
4F0S
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Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
分子名称: 5-methylthioadenosine/S-adenosylhomocysteine deaminase, CHLORIDE ION, INOSINE, ...
著者Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-05-04
公開日2012-06-06
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
To be Published
1K1U
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Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance
分子名称: N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN
著者Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T.
登録日2001-09-25
公開日2002-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Combining mutations in HIV-1 protease to understand mechanisms of resistance.
Proteins, 48, 2002
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
分子名称: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
著者Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
登録日2012-05-09
公開日2013-05-15
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
1JWX
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Chalcone Synthase--F215S mutant
分子名称: CHALCONE SYNTHASE 2
著者Jez, J.M, Bowman, M.E, Noel, J.P.
登録日2001-09-05
公開日2002-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity.
Proc.Natl.Acad.Sci.USA, 99, 2002
1K07
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Native FEZ-1 metallo-beta-lactamase from Legionella gormanii
分子名称: ACETATE ION, FEZ-1 beta-lactamase, GLYCEROL, ...
著者Garcia-Saez, I, Mercuri, P.S, Kahn, R, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O.
登録日2001-09-18
公開日2003-01-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-[beta]-lactamase from Fluoribacter gormanii, in Native Form and in Complex with -Captopril
J.MOL.BIOL., 325, 2003
1M9O
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BU of 1m9o by Molmil
NMR structure of the first Zinc Binding domain of Nup475/TTP/TIS11
分子名称: Tristetraproline, ZINC ION
著者Amann, B.T, Worthington, M.T, Berg, J.M.
登録日2002-07-29
公開日2003-06-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A Cys3His Zinc-Binding Domain from Nup475/Tristetraproline: a Novel Fold with a Disklike Structure
Biochemistry, 42, 2003
4F5C
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Crystal structure of the spike receptor binding domain of a porcine respiratory coronavirus in complex with the pig aminopeptidase N ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Santiago, C, Reguera, J, Gaurav, M, Ordono, D, Enjuanes, L, Casasnovas, J.M.
登録日2012-05-13
公開日2012-08-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
1M1J
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Crystal structure of native chicken fibrinogen with two different bound ligands
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yang, Z, Kollman, J.M, Pandi, L, Doolittle, R.F.
登録日2002-06-19
公開日2002-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
Biochemistry, 40, 2001
1M7T
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Solution Structure and Dynamics of the Human-Escherichia coli Thioredoxin Chimera: Insights into Thermodynamic Stability
分子名称: Chimera of Human and E. coli thioredoxin
著者Dangi, B, Dobrodumov, A.V, Louis, J.M, Gronenborn, A.M.
登録日2002-07-22
公開日2002-09-25
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Solution Structure and Dynamics of the Human-Escherichia coli Thioredoxin Chimera: Insights into Thermodynamic Stability
Biochemistry, 41, 2002
4F2M
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Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
著者Reguera, J, Santiago, C, Mudgal, G, Ordono, D, Enjuanes, L, Casasnovas, J.M.
登録日2012-05-08
公開日2012-08-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
1LPH
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BU of 1lph by Molmil
LYS(B28)PRO(B29)-HUMAN INSULIN
分子名称: CHLORIDE ION, INSULIN, PHENOL, ...
著者Ciszak, E, Beals, J.M, Frank, B.H, Baker, J.C, Carter, N.D, Smith, G.D.
登録日1995-04-19
公開日1996-06-20
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin.
Structure, 3, 1995
1LWI
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3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE FROM RATTUS NORVEGICUS
分子名称: 3-ALPHA-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bennett, M.J, Schlegel, B.P, Jez, J.M, Penning, T.M, Lewis, M.
登録日1996-02-24
公開日1996-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+.
Biochemistry, 35, 1996
1M18
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: Histone H2A.1, Histone H2B.1, Histone H3.2, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1LVZ
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METARHODOPSIN II BOUND STRUCTURE OF C-TERMINAL PEPTIDE OF ALPHA-SUBUNIT OF TRANSDUCIN
分子名称: Guanine nucleotide-binding protein G(T), alpha-1 subunit
著者Koenig, B.W, Kontaxis, G, Mitchell, D.C, Louis, J.M, Litman, B.J, Bax, A.
登録日2002-05-30
公開日2002-09-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings.
J.Mol.Biol., 322, 2002
1M19
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1MM3
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Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF
分子名称: Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION
著者Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P.
登録日2002-09-02
公開日2003-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Engineering a Protein Scaffold from a PHD Finger
structure, 11, 2003
1M0I
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Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site
分子名称: SULFATE ION, endodeoxyribonuclease I
著者Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M.
登録日2002-06-13
公開日2002-12-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I
Embo J., 21, 2002
1IDC
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ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY
分子名称: 2-OXALOSUCCINIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDF
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ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME
分子名称: ISOCITRATE DEHYDROGENASE
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995

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